KPNA1 Monoclonal Antibody (114-E12) | Invitrogen 37-0800 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KPNA1 Monoclonal Antibody (114-E12)

catalog :

37-0800

quantity :

100 µg

price :

US 450.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

114-E12

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:250; fig 3	Ghosh S, Vassilev A, Zhang J, Zhao Y, DePamphilis M. Assembly of the human origin recognition complex occurs through independent nuclear localization of its components. J Biol Chem. 2011;286:23831-41 pubmed publisher
	Khosravi B, LaClair K, Riemenschneider H, Zhou Q, Frottin F, Mareljic N, et al. Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD. EMBO J. 2020;39:e102811 pubmed publisher

product information

Product Type :

Antibody

Product Name :

KPNA1 Monoclonal Antibody (114-E12)

Catalog # :

37-0800

Quantity :

100 µg

Price :

US 450.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 2 µg/mL

Species :

Human, Mouse

Clone :

114-E12

Isotype :

IgG1

Storage :

-20°C

Description :

Recombination activating proteins RAG1 and RAG2 regulate and mediate VJ recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in VJ recombination. Two transcript variants, one protein-coding and the other not, have been found for this gene.

Immunogen :

GST fusion protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 2 µg/mL

Aliases :

AW494490; IMA2; Importin alpha 2; importin alpha 5; Importin alpha P1; importin alpha-5; importin alpha-S1; importin subunit alpha-1; importin subunit alpha-5; Importin subunit alpha-5, N-terminally processed; importin-alpha-S1; IPOA 1; IPOA1; IPOA5; karyopherin (importin) alpha 1; Karyopherin A2; karyopherin alpha 1; karyopherin alpha 1 (importin alpha 5); karyopherin subunit alpha 1; karyopherin subunit alpha-1; karyopherin/importin alpha-1; KPNA1; KPNA2; m-importin-alpha-S1; mSRP1; NPI1; NPI-1; Nucleoprotein interactor 1; RAG cohort 1; RAG cohort protein 2; RCH 1; RCH1; RCH2; recombination activating gene cohort 2; SRP 1; SRP1; SRP1 alpha; SRP1-beta

more info or order :

Invitrogen product webpage