product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD31 Monoclonal Antibody (MEM-05)
catalog :
37-0700
quantity :
100 ug
price :
US 451.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MEM-05
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 20
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 3
Gao Y, Li J, Qiao N, Meng Q, Zhang M, Wang X, et al. Adrenomedullin blockade suppresses sunitinib-resistant renal cell carcinoma growth by targeting the ERK/MAPK pathway. Oncotarget. 2016;7:63374-63387 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2c
Ji H, Atchison L, Chen Z, Chakraborty S, Jung Y, Truskey G, et al. Transdifferentiation of human endothelial progenitors into smooth muscle cells. Biomaterials. 2016;85:180-194 pubmed publisher
  • western blot; rat; fig 4
Szulcek R, Happé C, Rol N, Fontijn R, Dickhoff C, Hartemink K, et al. Delayed Microvascular Shear Adaptation in Pulmonary Arterial Hypertension. Role of Platelet Endothelial Cell Adhesion Molecule-1 Cleavage. Am J Respir Crit Care Med. 2016;193:1410-20 pubmed publisher
  • immunohistochemistry; human; 1:25; fig 3
Eren G, Kantarcı A, Sculean A, Atilla G. Vascularization after treatment of gingival recession defects with platelet-rich fibrin or connective tissue graft. Clin Oral Investig. 2016;20:2045-2053 pubmed
  • immunohistochemistry; human; fig 4
Garvin K, Dalecki D, Yousefhussien M, Helguera M, Hocking D. Spatial patterning of endothelial cells and vascular network formation using ultrasound standing wave fields. J Acoust Soc Am. 2013;134:1483-90 pubmed publisher
  • immunocytochemistry; human; fig 6
Kang S, Carlon T, Jantzen A, Lin F, Ley M, Allen J, et al. Isolation of functional human endothelial cells from small volumes of umbilical cord blood. Ann Biomed Eng. 2013;41:2181-92 pubmed publisher
  • immunocytochemistry; human; fig 7
Garvin K, Dalecki D, Hocking D. Vascularization of three-dimensional collagen hydrogels using ultrasound standing wave fields. Ultrasound Med Biol. 2011;37:1853-64 pubmed publisher
  • immunocytochemistry; human; fig 1
Lindquist J, Cheresh D, Snyder E. Derivation of vasculature from embryonic stem cells. Curr Protoc Stem Cell Biol. 2010;Chapter 1:Unit 1F.9 pubmed publisher
  • flow cytometry; mouse
Banerjee I, Fuseler J, Intwala A, Baudino T. IL-6 loss causes ventricular dysfunction, fibrosis, reduced capillary density, and dramatically alters the cell populations of the developing and adult heart. Am J Physiol Heart Circ Physiol. 2009;296:H1694-704 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Wei F, Cao S, Ren X, Liu H, Yu J, Li H, et al. Efficient antiproliferative and antiangiogenic effects on human ovarian cancer growth by gene transfer of attenuated mutants of Shiga-like toxin I. Int J Gynecol Cancer. 2008;18:677-91 pubmed
  • flow cytometry; mouse; fig 1
Banerjee I, Fuseler J, Price R, Borg T, Baudino T. Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse. Am J Physiol Heart Circ Physiol. 2007;293:H1883-91 pubmed
Niu Y, Galluzzi M, Fu M, Hu J, Xia H. In vivo performance of electrospun tubular hyaluronic acid/collagen nanofibrous scaffolds for vascular reconstruction in the rabbit model. J Nanobiotechnology. 2021;19:349 pubmed publisher
Niu Y, Galluzzi M. Hyaluronic Acid/Collagen Nanofiber Tubular Scaffolds Support Endothelial Cell Proliferation, Phenotypic Shape and Endothelialization. Nanomaterials (Basel). 2021;11: pubmed publisher
Yonezawa K, Kawaguchi M, Kaneuji A, Ichiseki T, Iinuma Y, Kawamura K, et al. Evaluation of Antibacterial and Cytotoxic Properties of a Fluorinated Diamond-Like Carbon Coating for the Development of Antibacterial Medical Implants. Antibiotics (Basel). 2020;9: pubmed publisher
Wei F, Wang A, Wang Q, Han W, Rong R, Wang L, et al. Plasma endothelial cells-derived extracellular vesicles promote wound healing in diabetes through YAP and the PI3K/Akt/mTOR pathway. Aging (Albany NY). 2020;12:12002-12018 pubmed publisher
Domke L, Franke W. The cell-cell junctions of mammalian testes: II. The lamellar smooth muscle monolayer cells of the peritubular wall are laterally connected by vertical adherens junctions-a novel architectonic cell-cell junction system. Cell Tissue Res. 2019;375:451-482 pubmed publisher
Follain G, Osmani N, Azevedo A, Allio G, Mercier L, Karreman M, et al. Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells. Dev Cell. 2018;45:33-52.e12 pubmed publisher
Gaston J, Bischel L, Fitzgerald L, Cusick K, Ringeisen B, Pirlo R. Gene Expression Changes in Long-Term In Vitro Human Blood-Brain Barrier Models and Their Dependence on a Transwell Scaffold Material. J Healthc Eng. 2017;2017:5740975 pubmed publisher
Wong A, Searson P. Mitosis-Mediated Intravasation in a Tissue-Engineered Tumor-Microvessel Platform. Cancer Res. 2017;77:6453-6461 pubmed publisher
Ivkovic S, Yoon B, Popoff S, Safadi F, Libuda D, Stephenson R, et al. Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development. 2003;130:2779-91 pubmed
product information
Product Type :
Antibody
Product Name :
CD31 Monoclonal Antibody (MEM-05)
Catalog # :
37-0700
Quantity :
100 ug
Price :
US 451.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
Species :
Human
Clone :
MEM-05
Isotype :
IgG1
Storage :
-20 C
Description :
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Immunogen :
Leukocytes from LGL-type leukemia patient.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
Aliases :
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA