CKS2 Monoclonal Antibody (1F7G5) | Invitrogen 37-0300 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CKS2 Monoclonal Antibody (1F7G5)

catalog :

37-0300

quantity :

100 µg

price :

US 430

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1F7G5

reactivity :

human

application :

western blot, ELISA, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 2	Rother K, Dengl M, Lorenz J, Tschop K, Kirschner R, Mossner J, et al. Gene expression of cyclin-dependent kinase subunit Cks2 is repressed by the tumor suppressor p53 but not by the related proteins p63 or p73. FEBS Lett. 2007;581:1166-72 pubmed
immunohistochemistry - paraffin section; human	Lyng H, Brøvig R, Svendsrud D, Holm R, Kaalhus O, Knutstad K, et al. Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer. BMC Genomics. 2006;7:268 pubmed
	Catal xe0 P, Groen N, Dehnen J, Soares E, van Velthoven A, Nuijts R, et al. Single cell transcriptomics reveals the heterogeneity of the human cornea to identify novel markers of the limbus and stroma. Sci Rep. 2021;11:21727 pubmed publisher
	Jonsson M, Fjeldbo C, Holm R, Stokke T, Kristensen G, Lyng H. Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer. Neoplasia. 2019;21:353-362 pubmed publisher
	Grey W, Ivey A, Milne T, Haferlach T, Grimwade D, Uhlmann F, et al. The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability. Biochim Biophys Acta Mol Cell Res. 2018;1865:105-116 pubmed publisher
	Kang M, Kim J, Kim J, Kim S, Kim Y, Yeom Y, et al. Upregulation of the cycline kinase subunit CKS2 increases cell proliferation rate in gastric cancer. J Cancer Res Clin Oncol. 2009;135:761-9 pubmed publisher
	Rother K, Li Y, Tschop K, Kirschner R, Müller G, Mossner J, et al. Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is downregulated by p53 but not by p63 or p73. Cell Cycle. 2007;6:853-62 pubmed

product information

Product Type :

Antibody

Product Name :

CKS2 Monoclonal Antibody (1F7G5)

Catalog # :

37-0300

Quantity :

100 µg

Price :

US 430

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

1F7G5

Isotype :

IgG1

Storage :

-20°C

Description :

CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein. [provided by RefSeq, Jul 2008]

Immunogen :

A synthetic peptide derived from the C-terminal region of human CKS2.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

1110038L14Rik; CDC28 protein kinase 2; CDC28 protein kinase regulatory subunit 2; CKS1(S. cerevisiae Cdc28/Cdc2 kinase subunit) homolog-2; CKS2; CKS-2; CKSHS2; Cyclin-dependent kinases regulatory subunit 2; RGD1562047; RP11-8C21.2

more info or order :

Invitrogen product webpage