CKS1 Monoclonal Antibody (4G12G7) | Invitrogen 37-0200 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CKS1 Monoclonal Antibody (4G12G7)

catalog :

37-0200

quantity :

100 µg

price :

US 430

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4G12G7

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:250	Kim J, Kim H, Park J, Park D, Cho Y, Sohn C, et al. Epidermal growth factor upregulates Skp2/Cks1 and p27(kip1) in human extrahepatic cholangiocarcinoma cells. World J Gastroenterol. 2014;20:755-73 pubmed publisher
	Grey W, Ivey A, Milne T, Haferlach T, Grimwade D, Uhlmann F, et al. The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability. Biochim Biophys Acta Mol Cell Res. 2018;1865:105-116 pubmed publisher
	Chen Q, Xie W, Kuhn D, Voorhees P, Lopez Girona A, Mendy D, et al. Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy. Blood. 2008;111:4690-9 pubmed publisher
	Kitajima S, Kudo Y, Ogawa I, Bashir T, Kitagawa M, Miyauchi M, et al. Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation. Am J Pathol. 2004;165:2147-55 pubmed

product information

Product Type :

Antibody

Product Name :

CKS1 Monoclonal Antibody (4G12G7)

Catalog # :

37-0200

Quantity :

100 µg

Price :

US 430

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

4G12G7

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.

Immunogen :

Synthetic peptide derived from the C-terminal region of the human Cks1 protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Aliases :

2410005G18Rik; 2610005D03Rik; AA407784; CDC28 protein kinase 1; CDC28 protein kinase 1B; CDC28 protein kinase regulatory subunit 1; CDC28 protein kinase regulatory subunit 1B; CDC2-associated protein CKS1; cell division control protein CKS1; CKS1; CKS-1; Cks1b; ckshs1; cyclin-dependent kinase regulatory subunit 1; cyclin-dependent kinases regulatory subunit 1; NB4 apoptosis/differentiation related protein; PNAS-143; PNAS-16; PNAS-18; RGD1561797; Sid 1334; sid1334; Unknown (protein for MGC:142665); zgc:101026

more info or order :

Invitrogen product webpage