CD8a Monoclonal Antibody (RPA-T8), Brilliant Ultra Violet 805, eBioscience | Invitrogen 368-0088-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD8a Monoclonal Antibody (RPA-T8), Brilliant Ultra Violet 805, eBioscience

catalog :

368-0088-42

quantity :

100 Tests

price :

US 424.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RPA-T8

The same clone is also sold as:

BD Biosciences: 560347, 555369, 555363, 561952, 560775, 563822, 562428, 557750, 561948, 560774, 557945, 558207, 562282, 555367, 561026, 563823, 561951, 563795, 561426, 557746, 561421, 563821, 561949, 557084, 555368, 555365, 561953, 560348, 555366, 560662, 557760, 561947, 562311, 561950, 557708, 655111, 561453, 555364, 560917, 557086, 562429, 557085
Rockland Immunochemicals: 200-326-M64, 200-302-M64
Tonbo Biosciences: 70-0088
R&D Systems: FAB3802G-100UG, FAB3802U-100UG, FAB3802S-100UG, FAB3802T-100UG, MAB3802-100, FAB3802R-100UG, FAB3802V-100UG, FAB3802N-100UG
BioLegend: 301040, 301029, 301033, 301066, 301079, 301048, 301026, 301080, 301031, 301074, 301016, 301042, 301067, 301064, 301004, 301073, 301035, 301045, 301062, 301076, 301075, 301010, 301065, 301030, 301053, 301078, 301046, 301006, 301044, 301014, 301037, 301051, 301009, 301028, 301077, 301071, 301038, 301022, 301049, 301002, 301023, 301057, 301069, 301005, 301007, 301025, 301027, 301060, 301056, 301003, 301024, 301021, 301047, 301039, 301058, 301041, 301008, 301012, 301050, 301036, 301043, 301032, 301015
Bio-Rad: MCA4609T
Novus Biologicals: NBP2-80659, NBP2-25195

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

CD8a Monoclonal Antibody (RPA-T8), Brilliant Ultra Violet 805, eBioscience

Catalog # :

368-0088-42

Quantity :

100 Tests

Price :

US 424.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.125 ug)/test

Species :

Human

Clone :

RPA-T8

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation. CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules. CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I. CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha. Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation. Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells. Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.125 ug)/test

Aliases :

BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein