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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CKS1 Polyclonal Antibody
catalog :
36-6800
quantity :
100 ug
price :
US 451.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; fig 6
  • western blot; human; 1:500; fig 1
Pavlides S, Lecanda J, Daubriac J, Pandya U, Gama P, Blank S, et al. TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth. Cell Cycle. 2016;15:931-47 pubmed publisher
Oh E, Kim H, Kim C, Lee J, Kim C, Lee J, et al. NQO1 regulates cell cycle progression at the G2/M phase. Theranostics. 2023;13:873-895 pubmed publisher
Bibbo S, Lamolinara A, Capone E, Purgato S, Tsakaneli A, Panella V, et al. Repurposing a psychoactive drug for children with cancer: p27Kip1-dependent inhibition of metastatic neuroblastomas by Prozac. Oncogenesis. 2020;9:3 pubmed publisher
Chai Z, Wang L, Zheng Y, Liang N, Wang X, Zheng Y, et al. PADI3 plays an antitumor role via the Hsp90/CKS1 pathway in colon cancer. Cancer Cell Int. 2019;19:277 pubmed publisher
Peng Y, Wu W, Chen L, Kuo K, Tsai C, Huang Y, et al. Upregulation of cyclin-dependent kinase inhibitors CDKN1B and CDKN1C in hepatocellular carcinoma-derived cells via goniothalamin-mediated protein stabilization and epigenetic modifications. Toxicol Rep. 2015;2:322-332 pubmed publisher
Daubriac J, Pandya U, Huang K, Pavlides S, Gama P, Blank S, et al. Hormonal and Growth Regulation of Epithelial and Stromal Cells From the Normal and Malignant Endometrium by Pigment Epithelium-Derived Factor. Endocrinology. 2017;158:2754-2773 pubmed publisher
Hamdi A, Lesnard A, Suzanne P, Robert T, Miteva M, Pellerano M, et al. Tampering with cell division by using small-molecule inhibitors of CDK-CKS protein interactions. Chembiochem. 2015;16:432-9 pubmed publisher
Chayka O, D Acunto C, Middleton O, Arab M, Sala A. Identification and pharmacological inactivation of the MYCN gene network as a therapeutic strategy for neuroblastic tumor cells. J Biol Chem. 2015;290:2198-212 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CKS1 Polyclonal Antibody
Catalog # :
36-6800
Quantity :
100 ug
Price :
US 451.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
ELISA: Assay-dependent, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Species :
Human
Isotype :
IgG
Storage :
-20 C
Description :
CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.
Immunogen :
Synthetic peptide derived from the C-terminal region of human and mouse Cks1.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Aliases :
2410005G18Rik; 2610005D03Rik; AA407784; CDC28 protein kinase 1; CDC28 protein kinase 1B; CDC28 protein kinase regulatory subunit 1; CDC28 protein kinase regulatory subunit 1B; CDC2-associated protein CKS1; cell division control protein CKS1; CKS1; CKS-1; Cks1b; ckshs1; cyclin-dependent kinase regulatory subunit 1; cyclin-dependent kinases regulatory subunit 1; NB4 apoptosis/differentiation related protein; PNAS-143; PNAS-16; PNAS-18; RGD1561797; Sid 1334; sid1334; Unknown (protein for MGC:142665); zgc:101026
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA