EZH2 Polyclonal Antibody | Invitrogen 36-6300 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EZH2 Polyclonal Antibody

catalog :

36-6300

quantity :

100 ug

price :

US 471.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:125; loading ...; fig 7d western blot; human; 1:250; loading ...; fig 4b	Goto Y, Kurozumi A, Nohata N, Kojima S, Matsushita R, Yoshino H, et al. The microRNA signature of patients with sunitinib failure: regulation of UHRF1 pathways by microRNA-101 in renal cell carcinoma. Oncotarget. 2016;7:59070-59086 pubmed publisher
	Chi Y, Xin H, Liu Z. Exosomal lncRNA UCA1 Derived From Pancreatic Stellate Cells Promotes Gemcitabine Resistance in Pancreatic Cancer via the SOCS3/EZH2 Axis. Front Oncol. 2021;11:671082 pubmed publisher
	Akkouche A, Moodad S, Hleihel R, Skayneh H, Chambeyron S, El Hajj H, et al. In vivo antagonistic role of the Human T-Cell Leukemia Virus Type 1 regulatory proteins Tax and HBZ. PLoS Pathog. 2021;17:e1009219 pubmed publisher
	Namjan A, Techasen A, Loilome W, Sa Ngaimwibool P, Jusakul A. ARID1A alterations and their clinical significance in cholangiocarcinoma. Peerj. 2020;8:e10464 pubmed publisher
	Yue Z, Chen J, Lian H, Pei J, Li Y, Chen X, et al. PDGFR-β Signaling Regulates Cardiomyocyte Proliferation and Myocardial Regeneration. Cell Rep. 2019;28:966-978.e4 pubmed publisher
	Galvis L, Holik A, Short K, Pasquet J, Lun A, Blewitt M, et al. Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung. Development. 2015;142:1458-69 pubmed publisher
	de la Cruz Hernandez E, Medina Franco J, Trujillo J, Chavez Blanco A, Domínguez Gómez G, Perez Cardenas E, et al. Ribavirin as a tri-targeted antitumor repositioned drug. Oncol Rep. 2015;33:2384-92 pubmed publisher

product information

Product Type :

Antibody

Product Name :

EZH2 Polyclonal Antibody

Catalog # :

36-6300

Quantity :

100 ug

Price :

US 471.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ChIP Assay: 2.5 ug/10^6 cells, ELISA: Assay-dependent, Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1:500

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).

Immunogen :

Synthetic peptide derived from the internal region of the human EZH2 (ENX1) protein.

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 2.5 ug/10^6 cells, ELISA: Assay-dependent, Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1:500

Aliases :

an; enhancer of zeste 2 polycomb repressive complex 2 subunit; enhancer of zeste homolog 2; enhancer of zeste homolog 2 (Drosophila); ENX 1; ENX1; Enx-1; Enx1h; EZH 2; EZH1; EZH2; EZH-2; EZH2b; histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; lysine N-methyltransferase 6; mKIAA4065; OTTHUMP00000213774; OTTHUMP00000213778; OTTHUMP00000213779; OTTHUMP00000213780; WVS; WVS2

more info or order :

Invitrogen product webpage