This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Syndecan 2 Polyclonal Antibody
catalog :
36-6200
quantity :
100 ug
price :
US 471.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 3
Reference
Beauvais D, Nelson S, Adams K, Stueven N, Jung O, Rapraeger A. Plasma membrane proteoglycans syndecan-2 and syndecan-4 engage with EGFR and RON kinase to sustain carcinoma cell cycle progression. J Biol Chem. 2022;298:102029 pubmed publisher
Park H, Kim M, Kim H, Lee Y, Seo Y, Pham C, et al. Heparan sulfate proteoglycans (HSPGs) and chondroitin sulfate proteoglycans (CSPGs) function as endocytic receptors for an internalizing anti-nucleic acid antibody. Sci Rep. 2017;7:14373 pubmed publisher
Mansouri R, Jouan Y, Hay E, Blin Wakkach C, Frain M, Ostertag A, et al. Osteoblastic heparan sulfate glycosaminoglycans control bone remodeling by regulating Wnt signaling and the crosstalk between bone surface and marrow cells. Cell Death Dis. 2017;8:e2902 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Syndecan 2 Polyclonal Antibody
Catalog # :
36-6200
Quantity :
100 ug
Price :
US 471.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
ELISA: Assay-dependent, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1-2 ug/mL
Species :
Human
Isotype :
IgG
Storage :
-20 C
Description :
Syndecans are heparan sulfate proteoglycans (HSPGs) that are involved in cell adhesion, tissue morphogenesis, differentiation, and act as low affinity co-receptors of soluble growth factors. It is involved in the mitogenic activity and signaling of Granulocyte-Macrophage Colony-stimulating factor in osteoblasts, and has been shown to have a regulatory role in matrix assembly. Syndecan-2 is expressed at epithelial-mesenchymal interfaces, and prechondrogenic and preosteogenic mesenchymal condensations, which are areas of high morphogenetic activity.
Immunogen :
Synthetic peptide derived from the internal region of human syndecan-2 (fibroglycan).
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1-2 ug/mL
Aliases :
4833414L08Rik; AA960457; CD362; cell surface-associated heparan sulfate proteoglycan 1; fibroglycan; heparan sulfate proteoglycan 1, cell surface-associated; heparan sulfate proteoglycan 1, cell surface-associated (fibroglycan); heparan sulfate proteoglycan core protein; HSPG; Hspg1; Ryudocan/syndecan 2; Sdc2; SYND2; syndecan 2; syndecan proteoglycan 2; syndecan-2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA