LRP5 Polyclonal Antibody | Invitrogen 36-5400 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LRP5 Polyclonal Antibody

catalog :

36-5400

quantity :

100 ug

price :

US 471.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 2

Reference
Chen G, Long C, Wang S, Wang Z, Chen X, Tang W, et al. Circular RNA circStag1 promotes bone regeneration by interacting with HuR. Bone Res. 2022;10:32 pubmed publisher
Kim S, Da H, Li Z, Kushwaha P, Beil C, Mei L, et al. Lrp4 expression by adipocytes and osteoblasts differentially impacts sclerostin's endocrine effects on body composition and glucose metabolism. J Biol Chem. 2019;294:6899-6911 pubmed publisher

product information

Product Type :

Antibody

Product Name :

LRP5 Polyclonal Antibody

Catalog # :

36-5400

Quantity :

100 ug

Price :

US 471.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos. Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins. Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading Axin degradation and beta catenin stabilization.

Immunogen :

Synthetic peptide derived from the C-terminal region of the human LRP5 protein. This intracellular region is identical to the corresponding mouse and rat LRP5 amino acid sequences.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent

Aliases :

BMND1; EVR1; EVR4; HBM; HGNC:6697; LDL receptor related protein 5; low density lipoprotein receptor-related protein 5; low density lipoprotein receptor-related protein 7; low-density lipoprotein receptor-related protein 5; Low-density lipoprotein receptor-related protein 7; LR3; Lrp5; LRP-5; LRP7; LRP-7; mKIAA4142; OPPG; OPS; OPTA1; VBCH2