Connexin 40 Polyclonal Antibody | Invitrogen 36-4900 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Connexin 40 Polyclonal Antibody

catalog :

36-4900

quantity :

100 µg

price :

425 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:300; loading ...; fig s8	Fang J, Coon B, Gillis N, Chen Z, Qiu J, Chittenden T, et al. Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nat Commun. 2017;8:2149 pubmed publisher
immunohistochemistry; mouse; 1:200; loading ...; fig 2a western blot; mouse; 1:1000; loading ...; fig 4a	Gemel J, Su Z, Gileles Hillel A, Khalyfa A, Gozal D, Beyer E. Intermittent hypoxia causes NOX2-dependent remodeling of atrial connexins. BMC Cell Biol. 2017;18:7 pubmed publisher
immunocytochemistry; mouse; 1:200; loading ...; fig 1b	Guo R, Si R, Scott B, Makino A. Mitochondrial connexin40 regulates mitochondrial calcium uptake in coronary endothelial cells. Am J Physiol Cell Physiol. 2017;312:C398-C406 pubmed publisher
immunocytochemistry; human; 1:200; loading ...; fig 4a	Xu Q, Lin X, Matiukas A, Zhang X, Veenstra R. Specificity of the connexin W3/4 locus for functional gap junction formation. Channels (Austin). 2016;10:453-65 pubmed publisher
immunocytochemistry; human; 1:100; fig s11	Eng G, Lee B, Protas L, Gagliardi M, Brown K, Kass R, et al. Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. Nat Commun. 2016;7:10312 pubmed publisher
	Zhang W, Li X, Sun S, Zhang X. Implantation of engineered conduction tissue in the rat heart. Mol Med Rep. 2019;19:2687-2697 pubmed publisher
	Kundu S, Pushpakumar S, Sen U. MMP-9- and NMDA receptor-mediated mechanism of diabetic renovascular remodeling and kidney dysfunction: hydrogen sulfide is a key modulator. Nitric Oxide. 2015;46:172-85 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Connexin 40 Polyclonal Antibody

Catalog # :

36-4900

Quantity :

100 µg

Price :

425 USD

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunofluorescence: Assay Dependent, Immunohistochemistry (Frozen): 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

Connexin 40 (Cx40), belongs to the connexin family of gap junction proteins, which are expressed in pancreas, kidney, skeletal muscle, liver, placenta and heart. Connexin 40 is highly expressed in vascular endothelial cells, and the mammalian heart (specifically in the atrial myocardium, and the His-Purkinje conduction system). At least three other connexins are expressed in the heart, including Cx37 (endocardium), Cx43 (atrial and ventricular myocardium, and distal parts of the conduction system) and Cx45 (throughout the heart). Cx40 and Cx43 frequently co-localize in cells of the cardiovascular system and participate in the formation of heterotypic gap junction channels.

Immunogen :

Synthetic peptide derived from the C-terminal region of the mouse and rat Connexin 40 (Cx40) proteins. The human sequence at this location differs by only one amino acid.

Format :

Liquid

Applications w/Dilutions :

Immunofluorescence: Assay Dependent, Immunohistochemistry (Frozen): 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Aliases :

5730555N10Rik; ATFB11; Cnx40; connexin 40; connexin-40; Cx40; Cxn-40; Gap junction alpha-5 protein; gap junction membrane channel protein alpha 5; gap junction protein alpha 5; gap junction protein alpha 5 40kDa; gap junction protein, alpha 5; gap junction protein, alpha 5, 40kDa; gap junction protein, alpha 5, 40kDa (connexin 40); Gja5; Gja-5

more info or order :

Invitrogen product webpage