Human ApoE2 Recombinant Protein, PeproTech | Invitrogen 350-12-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human ApoE2 Recombinant Protein, PeproTech

catalog :

350-12-100UG

quantity :

100 ug

price :

US 93.50

citations: 5

Reference
Alam S, Wang F, Qian H, Kulka M. Apolipoprotein C3 facilitates internalization of cationic lipid nanoparticles into bone marrow-derived mouse mast cells. Sci Rep. 2023;13:431 pubmed publisher
Paavola K, Roda J, Lin V, Chen P, O Hollaren K, Ventura R, et al. The Fibronectin-ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells. Cancer Immunol Res. 2021;9:1283-1297 pubmed publisher
Chikazawa M, Yoshitake J, Lim S, Iwata S, Negishi L, Shibata T, et al. Glycolaldehyde is an endogenous source of lysine N-pyrrolation. J Biol Chem. 2020;295:7697-7709 pubmed publisher
Ramms B, Patel S, Nora C, Pessentheiner A, Chang M, Green C, et al. ApoC-III ASO Promotes Tissue LPL Activity in Absence of ApoE-Mediated TRL Clearance. J Lipid Res. 2019;: pubmed publisher
Tiaden A, Bahrenberg G, Mirsaidi A, Glanz S, BlÃ¼her M, Richards P. Novel Function of Serine Protease HTRA1 in Inhibiting Adipogenic Differentiation of Human Mesenchymal Stem Cells via MAP Kinase-Mediated MMP Upregulation. Stem Cells. 2016;34:1601-14 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human ApoE2 Recombinant Protein, PeproTech

Catalog # :

350-12-100UG

Quantity :

100 ug

Price :

US 93.50

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Functional Assay: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solubilization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in the liver and brain, and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. Its interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. It also binds with the LDL receptor (apo B/E). Defects in ApoE are a cause of hyperlipoproteinemia type III. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. E2 allele carriers had significantly lower levels of total cholesterol, low-density lipoprotein cholesterol, and non-high-density lipoprotein cholesterol, as well as increased ApoE levels.

Format :

Lyophilized

Applications w/Dilutions :

Functional Assay: Assay-dependent