Kaiso Monoclonal Antibody (6F) | Invitrogen 35-8500 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Kaiso Monoclonal Antibody (6F)

catalog :

35-8500

quantity :

100 ug

price :

US 451.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human, mouse, rat, dogs, chicken, domestic rabbit

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

citations: 1

Reference
Kondapalli J, Flozak A, Albuquerque M. Laminar shear stress differentially modulates gene expression of p120 catenin, Kaiso transcription factor, and vascular endothelial cadherin in human coronary artery endothelial cells. J Biol Chem. 2004;279:11417-24 pubmed

product information

Product Type :

Antibody

Product Name :

Kaiso Monoclonal Antibody (6F)

Catalog # :

35-8500

Quantity :

100 ug

Price :

US 451.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Canine, Chicken, Human, Mouse, Rabbit, Rat

Applications :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Canine, Chicken, Human, Mouse, Rabbit, Rat

Clone :

Isotype :

IgG1

Storage :

-20 C

Description :

This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensusKAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-alpha 2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.

Immunogen :

Fusion protein encompassing the N-terminus of mouse Kaiso

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

AW260253; E130014G12Rik; Kaiso; kaiso transcription factor; RGD1566309; RP23-322E15.9; Transcriptional regulator Kaiso; WUGSC:H_DJ525N14.1; Zbtb33; zinc finger and BTB domain containing 33; zinc finger and BTB domain-containing protein 33; zinc finger transcription factor Kaiso; ZNF348; ZNF-kaiso