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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
RAD51 Monoclonal Antibody (3C10)
catalog :
35-6500
quantity :
100 ug
price :
US 451.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3C10
reactivity :
human, bovine, pigs
application :
western blot, immunocytochemistry, immunoprecipitation, other
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; human
Alpay K, Farshchian M, Tuomela J, Sandholm J, Aittokallio K, Siljamäki E, et al. Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone. PLoS ONE. 2014;9:e105526 pubmed publisher
  • immunocytochemistry; human; 1:200; fig s1
  • western blot; human; 1:1000; fig s1
Shtam T, Kovalev R, Varfolomeeva E, Makarov E, Kil Y, Filatov M. Exosomes are natural carriers of exogenous siRNA to human cells in vitro. Cell Commun Signal. 2013;11:88 pubmed publisher
Skvarova Kramarzova K, Osborn M, Webber B, Defeo A, McElroy A, Kim C, et al. CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells. Int J Mol Sci. 2017;18: pubmed publisher
Shtam T, Varfolomeeva I, Semenova E, Filatov M. [Human RAD51 recombinase: the role in the cell cycle checkpoint and cellular survival]. Tsitologiia. 2008;50:958-63 pubmed
product information
Product Type :
Antibody
Product Name :
RAD51 Monoclonal Antibody (3C10)
Catalog # :
35-6500
Quantity :
100 ug
Price :
US 451.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Bovine, Human, Porcine
Applications :
Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Species :
Bovine, Human, Porcine
Clone :
3C10
Isotype :
IgG1
Storage :
-20 C
Description :
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
Immunogen :
Purified human RAD51 protein.
Format :
Liquid
Applications w/Dilutions :
Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Aliases :
AV304093; BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51; DNA repair protein RAD51 homolog 1; DNA repair protein RAD51 homolog A; DNA repair protein rhp51; FANCR; homolog to S.cerevisiae; HRAD51; HsRad51; HsT16930; MGC128559 protein; MRMV2; MUT5; rad51; RAD51 homolog; RAD51 homolog (RecA homolog); RAD51 homolog (RecA homolog, E. coli); RAD51 homolog A; RAD51 recombinase; RAD51 recombinase L homeolog; rad51.1; rad51.L; rad51-1; RAD51A; rad51-a; rad51-b; Reca; RecA family recombinase Rhp51; RecA, E. coli, homolog of; RecA-like protein; recombinase RAD51; recombination protein A; RGD1563603; rhp51; SPAC644.14c; wu:fb38e12; xrad51; XRad51.1; YER095W; zgc:77754
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA