Tyrosinase Monoclonal Antibody (T311) | Invitrogen 35-6000 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Tyrosinase Monoclonal Antibody (T311)

catalog :

35-6000

quantity :

100 µg

price :

US 375.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

T311

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 1b western blot; human; 1:2000; loading ...; fig 8a	Carballo Carbajal I, Laguna A, Romero Gimenez J, Cuadros T, Bove J, Martinez Vicente M, et al. Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis. Nat Commun. 2019;10:973 pubmed publisher
western blot; human	Abad S, Wieërs G, Colau D, Wildmann C, Delair E, Dhote R, et al. Absence of recognition of common melanocytic antigens by T cells isolated from the cerebrospinal fluid of a Vogt-Koyanagi-Harada patient. Mol Vis. 2014;20:956-69 pubmed
immunocytochemistry; mouse; 1:50 western blot; mouse; 1:1000	Nakajima H, Nagata T, Koga S, Imokawa G. Reduced glutathione disrupts the intracellular trafficking of tyrosinase and tyrosinase-related protein-1 but not dopachrome tautomerase and Pmel17 to melanosomes, which results in the attenuation of melanization. Arch Dermatol Res. 2014;306:37-49 pubmed publisher
flow cytometry; human; 1:50; fig 2	Richards J, Treisman J, Garlie N, Hanson J, Oaks M. Flow cytometry assessment of residual melanoma cells in tumor-infiltrating lymphocyte cultures. Cytometry A. 2012;81:374-81 pubmed publisher
immunohistochemistry - paraffin section; human; tbl 4	Tjin E, Konijnenberg D, Krebbers G, Mallo H, Drijfhout J, Franken K, et al. T-cell immune function in tumor, skin, and peripheral blood of advanced stage melanoma patients: implications for immunotherapy. Clin Cancer Res. 2011;17:5736-47 pubmed publisher
western blot; human; 1:500; fig 2	Nordgaard C, Karunadharma P, Feng X, Olsen T, Ferrington D. Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration. Invest Ophthalmol Vis Sci. 2008;49:2848-55 pubmed publisher
	Kammeyer A, Willemsen K, Ouwerkerk W, Bakker W, Ratsma D, Pronk S, et al. Mechanism of action of 4-substituted phenols to induce vitiligo and antimelanoma immunity. Pigment Cell Melanoma Res. 2019;32:540-552 pubmed publisher
	Kodet O, Dvořánková B, Krejci E, Szabo P, Dvorak P, Stork J, et al. Cultivation-dependent plasticity of melanoma phenotype. Tumour Biol. 2013;34:3345-55 pubmed publisher
	Chen Y, Stockert E, Tsang S, Coplan K, Old L. Immunophenotyping of melanomas for tyrosinase: implications for vaccine development. Proc Natl Acad Sci U S A. 1995;92:8125-9 pubmed

product information

Product Type :

Antibody

Product Name :

Tyrosinase Monoclonal Antibody (T311)

Catalog # :

35-6000

Quantity :

100 µg

Price :

US 375.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunohistochemistry: Assay-dependent, Western Blot: 1:250

Species :

Human, Mouse

Clone :

T311

Isotype :

IgG2a, kappa

Storage :

-20°C

Description :

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

Immunogen :

Recombinant tyrosinase protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: Assay-dependent, Western Blot: 1:250

Aliases :

albino; albino locus protein; ATN; C; CMM8; LB24-AB; monophenol monooxygenase; Oca1; OCA1A; OCAIA; oculocutaneous albinism IA; SHEP3; SK29-AB; skc35; Tumor rejection antigen AB; TYR; Tyrosinase; tyrosinase (oculocutaneous albinism IA); tyrosinase precursor

more info or order :

Invitrogen product webpage