PAR1 Monoclonal Antibody (ATAP2) | Invitrogen 35-2200 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PAR1 Monoclonal Antibody (ATAP2)

catalog :

35-2200

quantity :

100 ug

price :

US 451.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ATAP2

reactivity :

human

application :

ELISA, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; fig 3	Gramling M, Beaulieu L, Church F. Activated protein C enhances cell motility of endothelial cells and MDA-MB-231 breast cancer cells by intracellular signal transduction. Exp Cell Res. 2010;316:314-28 pubmed publisher
immunohistochemistry - paraffin section; human; fig 2	Materazzi S, Pellerito S, Di Serio C, Paglierani M, Naldini A, Ardinghi C, et al. Analysis of protease-activated receptor-1 and -2 in human scar formation. J Pathol. 2007;212:440-9 pubmed
immunohistochemistry - paraffin section; human; 1:50; tbl 1	Ketabchi S, Massi D, Ficarra G, Rubino I, Franchi A, Paglierani M, et al. Expression of protease-activated receptor-1 and -2 in orofacial granulomatosis. Oral Dis. 2007;13:419-25 pubmed
blocking or activating experiments; human; 10 ug/ml; fig 6	Beaulieu L, Church F. Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1. Exp Cell Res. 2007;313:677-87 pubmed
	O Brien P, Prevost N, Molino M, Hollinger M, Woolkalis M, Woulfe D, et al. Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1. J Biol Chem. 2000;275:13502-9 pubmed

product information

Product Type :

Antibody

Product Name :

PAR1 Monoclonal Antibody (ATAP2)

Catalog # :

35-2200

Quantity :

100 ug

Price :

US 451.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent

Species :

Human

Clone :

ATAP2

Isotype :

IgG1

Storage :

-20 C

Description :

Thrombin is a serine protease that is involved in platelet aggregation and blood coagulation. It is cleaved from its precursor, prothrombin, and converts fibrinogen to fibrin in the final step of the clotting cascade. Thrombin mediates its regulatory effects by activating cell surface G-protein coupled receptors which include PAR-1, PAR-2 and PAR3.

Immunogen :

A synthetic peptide corresponding to the N-terminal region of the human thrombin receptor PAR1.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent

Aliases :

AI482343; C HTR; Cf2r; coagulation factor II (thrombin) receptor; coagulation factor II receptor; coagulation factor II thrombin receptor; F2R; HTR; PAR1; PAR-1; protease activated receptor 1; protease-activated receptor 1; proteinase-activated receptor 1; Thrombin receptor; ThrR; TR; TRGPC

more info or order :

Invitrogen product webpage