This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
DMPK Polyclonal Antibody
catalog :
34-9900
quantity :
50 ug
price :
US 451.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, ELISA, immunocytochemistry
product information
Product Type :
Antibody
Product Name :
DMPK Polyclonal Antibody
Catalog # :
34-9900
Quantity :
50 ug
Price :
US 451.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Mouse
Applications :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent
Species :
Mouse
Isotype :
IgG
Storage :
-20 C
Description :
DMPK is a serine/threonine kinase expressed in various muscle and nerve tissues. Mutations in the untranslated region of the DMPK gene are a characteristic of myotonic dystrophy. The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region.
Immunogen :
Synthetic peptide from the C-terminal region of the mouse Myotonic Dystrophy Protein kinase (DMPK) protein
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent
Aliases :
DM; DM protein kinase; DM1; DM1 protein kinase; Dm15; DM1PK; DMK; DM-kinase; Dmpk; dystrophia myotonica kinase, B15; dystrophia myotonica protein kinase; dystrophia myotonica-protein kinase; MDPK; MT-PK; myotonic dystrophy associated protein kinase; myotonic dystrophy protein kinase; myotonin protein kinase A; myotonin-protein kinase; thymopoietin homolog
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA