TBX1 Polyclonal Antibody | Invitrogen 34-9800 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TBX1 Polyclonal Antibody

catalog :

34-9800

quantity :

100 ug

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 3

Reference
Funato N, Yanagisawa H. TBX1 targets the miR-200-ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties. Sci Rep. 2022;12:20188 pubmed publisher
Tian C, Johnson K. TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2020;457:91-103 pubmed publisher
Funato N, Nakamura M, Richardson J, Srivastava D, Yanagisawa H. Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Hum Mol Genet. 2015;24:424-35 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TBX1 Polyclonal Antibody

Catalog # :

34-9800

Quantity :

100 ug

Price :

US 451.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Mouse

Applications :

Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Mouse

Isotype :

IgG

Storage :

-20 C

Description :

TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Immunogen :

Synthetic peptide derived from the internal region of the mouse T-box 1 (Tbx1) protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

brachyury; CAFS; CATCH22; CTHM; DGCR; DGS; DORV; LOW QUALITY PROTEIN: T-box transcription factor TBX1; T-box 1; T-box 1 transcription factor C; T-box protein 1; T-box transcription factor 1; T-box transcription factor TBX1; T-box transcription factor TBX1; LOW QUALITY PROTEIN: T-box transcription factor TBX1; Tbx1; TBX1C; Testis-specific T-box protein; TGA; VCF; VCFS