| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; mouse; 2.5 ug/ml; loading ...
- western blot; mouse; 0.5 ug/ml; loading ...; fig 5a
| Szabo R, Ward J, Artunc F, Bugge T. EPCAM and TROP2 share a role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice. Biol Open. 2022;11: pubmed publisher |
- western blot; human; loading ...; fig s7
| Naydenov N, Lechuga S, Zalavadia A, Mukherjee P, Gordon I, Skvasik D, et al. P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer. Cells. 2022;11: pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 4d
- western blot; mouse; 1:20,000; loading ...; fig 4a
| Marincola Smith P, Choksi Y, Markham N, Hanna D, Zi J, Weaver C, et al. Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice. Am J Physiol Gastrointest Liver Physiol. 2021;320:G936-G957 pubmed publisher |
- immunocytochemistry; human; 1:100; loading ...; fig s7c
| Wijshake T, Zou Z, Chen B, Zhong L, Xiao G, Xie Y, et al. Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher |
- immunocytochemistry; dogs; fig 2
- western blot; dogs; fig 2
| Tokuda S, Hirai T, Furuse M. Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells. PLoS ONE. 2017;12:e0182521 pubmed publisher |
- western blot; dogs; 1:250; loading ...; fig 2d
| Raya Sandino A, Castillo Kauil A, Domínguez Calderón A, Alarcón L, Flores Benitez D, Cuellar Perez F, et al. Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function. Biochim Biophys Acta Mol Cell Res. 2017;1864:1714-1733 pubmed publisher |
- western blot; human; loading ...; fig 6c
| Wu C, Feng X, Lu M, Morimura S, Udey M. Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis. J Clin Invest. 2017;127:623-634 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1e
- immunocytochemistry; human; 1:200; loading ...; fig 2h
- western blot; human; 1:1000; loading ...; fig s2a
| Salomon J, Gaston C, Magescas J, Duvauchelle B, Canioni D, Sengmanivong L, et al. Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity. Nat Commun. 2017;8:13998 pubmed publisher |
- flow cytometry; human; 1:100; loading ...; fig 3a
| Torres Martínez A, Gallardo Vera J, Lara Holguin A, Montano L, Rendón Huerta E. Claudin-6 enhances cell invasiveness through claudin-1 in AGS human adenocarcinoma gastric cancer cells. Exp Cell Res. 2017;350:226-235 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2a
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6e
- western blot; mouse; 1:1000; loading ...; fig 6a
| Lin Z, Zhang Y, Xia Y, Xu X, Jiao X, Sun J. Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway. J Biol Chem. 2016;291:26837-26849 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3
| Virág J, Haberler C, Baksa G, Piurko V, Hegedûs Z, Reiniger L, et al. Region Specific Differences of Claudin-5 Expression in Pediatric Intracranial Ependymomas: Potential Prognostic Role in Supratentorial Cases. Pathol Oncol Res. 2017;23:245-252 pubmed publisher |
- western blot; mouse; 1:1000; fig 5
| Dianati E, Poiraud J, Weber Ouellette A, Plante I. Connexins, E-cadherin, Claudin-7 and ?-catenin transiently form junctional nexuses during the post-natal mammary gland development. Dev Biol. 2016;416:52-68 pubmed publisher |
- western blot; human; fig 2
| Teo W, Merino V, Cho S, Korangath P, Liang X, Wu R, et al. HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24. Oncogene. 2016;35:5539-5551 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 1
| Gu L, Cong J, Zhang J, Tian Y, Zhai X. A microwave antigen retrieval method using two heating steps for enhanced immunostaining on aldehyde-fixed paraffin-embedded tissue sections. Histochem Cell Biol. 2016;145:675-80 pubmed publisher |
- immunohistochemistry; human; fig 4
- western blot; human; fig 1c
| Barbáchano A, Fernández Barral A, Pereira F, Segura M, Ordóñez Morán P, Carrillo de Santa Pau E, et al. SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. Oncogene. 2016;35:2991-3003 pubmed publisher |
| Caneparo C, Chabaud S, Fradette J, Bolduc S. Engineered human organ-specific urethra as a functional substitute. Sci Rep. 2022;12:21346 pubmed publisher |
| Beanland B, McNeill E, Sequeira D, Xue H, Shroyer N, Speer A. Investigation of murine host sex as a biological variable in epithelial barrier function and muscle contractility in human intestinal organoids. FASEB J. 2022;36:e22613 pubmed publisher |
| Reiner J, Thiery J, Held J, Berlin P, Skarbaliene J, Vollmar B, et al. The dual GLP-1 and GLP-2 receptor agonist dapiglutide promotes barrier function in murine short bowel. Ann N Y Acad Sci. 2022;1514:132-141 pubmed publisher |
| Wei xdf F, Czichos C, Knobe L, Voges L, Bojarski C, Michel G, et al. MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier. Cells. 2022;11: pubmed publisher |
| Torres Pinzon D, Ralph D, Veiras L, McDonough A. Sex-specific adaptations to high-salt diet preserve electrolyte homeostasis with distinct sodium transporter profiles. Am J Physiol Cell Physiol. 2021;321:C897-C909 pubmed publisher |
| Droessler L, Cornelius V, Markov A, Amasheh S. Tumor Necrosis Factor Alpha Effects on the Porcine Intestinal Epithelial Barrier Include Enhanced Expression of TNF Receptor 1. Int J Mol Sci. 2021;22: pubmed publisher |
| Nelson J, McDonough A, Xiang Z, Ralph D, Robertson J, Giani J, et al. Local and downstream actions of proximal tubule angiotensin II signaling on Na+ transporters in the mouse nephron. Am J Physiol Renal Physiol. 2021;321:F69-F81 pubmed publisher |
| Kakiuchi A, Kakuki T, Ohwada K, Kurose M, Kondoh A, Obata K, et al. HDAC inhibitors suppress the proliferation, migration and invasiveness of human head and neck squamous cell carcinoma cells via p63‑mediated tight junction molecules and p21‑mediated growth arrest. Oncol Rep. 2021;45: pubmed publisher |
| Tinh N, Sitolo G, Yamamoto Y, Suzuki T. Citrus limon Peel Powder Reduces Intestinal Barrier Defects and Inflammation in a Colitic Murine Experimental Model. Foods. 2021;10: pubmed publisher |
| Faux M, King L, Kane S, Love C, Sieber O, Burgess A. APC regulation of ESRP1 and p120-catenin isoforms in colorectal cancer cells. Mol Biol Cell. 2021;32:120-130 pubmed publisher |
| El Chami C, Foster A, Johnson C, Clausen R, Cornwell P, Haslam I, et al. Organic osmolytes increase expression of specific tight junction proteins in skin and alter barrier function in keratinocytes. Br J Dermatol. 2021;184:482-494 pubmed publisher |
| Borisova M, Achasova K, Morozova K, Andreyeva E, Litvinova E, Ogienko A, et al. Mucin-2 knockout is a model of intercellular junction defects, mitochondrial damage and ATP depletion in the intestinal epithelium. Sci Rep. 2020;10:21135 pubmed publisher |
| Wu C, Lu M, Feng X, Nakato G, Udey M. Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins. Cells. 2020;9: pubmed publisher |
| Kumai A, Tsugami Y, Wakasa H, Suzuki N, Suzuki T, Nishimura T, et al. Adverse Effects of Coumestrol and Genistein on Mammary Morphogenesis and Future Milk Production Ability of Mammary Epithelial Cells. Adv Biosyst. 2020;4:e1900187 pubmed publisher |
| Dahiya N. Amyloid precursor-like protein 2 interacts with claudin-7 and affects ovarian cancer cell survival. Future Sci OA. 2020;6:FSO457 pubmed publisher |
| Ley D, Desseyn J, Gouyer V, Plet S, Tims S, Renes I, et al. Early life nutrition influences susceptibility to chronic inflammatory colitis in later life. Sci Rep. 2019;9:18111 pubmed publisher |
| Tulyeu J, Kumagai H, Jimbo E, Watanabe S, Yokoyama K, Cui L, et al. Probiotics Prevents Sensitization to Oral Antigen and Subsequent Increases in Intestinal Tight Junction Permeability in Juvenile-Young Adult Rats. Microorganisms. 2019;7: pubmed publisher |
| Miranda J, Martín Tapia D, Valdespino Vazquez Y, Alarcón L, Espejel Nuñez A, Guzmán Huerta M, et al. Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability. Cells. 2019;8: pubmed publisher |
| Dan Q, Shi Y, Rabani R, Venugopal S, Xiao J, Anwer S, et al. Claudin-2 suppresses GEF-H1, RHOA, and MRTF, thereby impacting proliferation and profibrotic phenotype of tubular cells. J Biol Chem. 2019;294:15446-15465 pubmed publisher |
| Otani T, Nguyen T, Tokuda S, Sugihara K, Sugawara T, Furuse K, et al. Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity. J Cell Biol. 2019;218:3372-3396 pubmed publisher |
| Luo S, Terciolo C, Bracarense A, Payros D, Pinton P, Oswald I. In vitro and in vivo effects of a mycotoxin, deoxynivalenol, and a trace metal, cadmium, alone or in a mixture on the intestinal barrier. Environ Int. 2019;132:105082 pubmed publisher |
| Yoon N, Dadson K, Dang T, Chu T, Noskovičová N, Hinz B, et al. Tracking adiponectin biodistribution via fluorescence molecular tomography indicates increased vascular permeability after streptozotocin-induced diabetes. Am J Physiol Endocrinol Metab. 2019;317:E760-E772 pubmed publisher |
| Danzinger S, Tan Y, Rudas M, Kastner M, Weingartshofer S, Muhr D, et al. Association of Cytokeratin 5 and Claudin 3 expression with BRCA1 and BRCA2 germline mutations in women with early breast cancer. BMC Cancer. 2019;19:695 pubmed publisher |
| Soroosh A, Rankin C, Polytarchou C, Lokhandwala Z, Patel A, Chang L, et al. microRNA-24 Is Elevated in Ulcerative Colitis Patients and Regulates Intestinal Epithelial Barrier Function. Am J Pathol. 2019;: pubmed publisher |
| Suzuki K, Sentani K, Tanaka H, Yano T, Suzuki K, Oshima M, et al. Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H pylori Infection. Cell Mol Gastroenterol Hepatol. 2019;8:119-142 pubmed publisher |
| Chen H, Lu R, Zhang Y, Sun J. Vitamin D Receptor Deletion Leads to the Destruction of Tight and Adherens Junctions in Lungs. Tissue Barriers. 2018;6:1-13 pubmed publisher |
| Barth A, Kim H, Riedel Kruse I. Regulation of epithelial migration by epithelial cell adhesion molecule requires its Claudin-7 interaction domain. PLoS ONE. 2018;13:e0204957 pubmed publisher |
| Shimada H, Satohisa S, Kohno T, Konno T, Takano K, Takahashi S, et al. Downregulation of lipolysis-stimulated lipoprotein receptor promotes cell invasion via claudin-1-mediated matrix metalloproteinases in human endometrial cancer. Oncol Lett. 2017;14:6776-6782 pubmed publisher |
| Nguyen N, Fernando S, Biette K, Hammer J, Capocelli K, Kitzenberg D, et al. TGF-β1 alters esophageal epithelial barrier function by attenuation of claudin-7 in eosinophilic esophagitis. Mucosal Immunol. 2018;11:415-426 pubmed publisher |
| Kern M, Günzel D, Aschenbach J, Tedin K, Bondzio A, Lodemann U. Altered Cytokine Expression and Barrier Properties after In Vitro Infection of Porcine Epithelial Cells with Enterotoxigenic Escherichia coli and Probiotic Enterococcus faecium. Mediators Inflamm. 2017;2017:2748192 pubmed publisher |
| Tokuda S, Furuse M. Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells. PLoS ONE. 2015;10:e0119869 pubmed publisher |
| Patsialou A, Wang Y, Pignatelli J, Chen X, Entenberg D, Oktay M, et al. Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGF? in claudin-low breast tumor cells. Oncogene. 2015;34:2721-31 pubmed publisher |
