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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MAG Polyclonal Antibody
catalog :
34-6200
quantity :
100 µg
price :
US 502
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 2c
Gerber D, Ghidinelli M, Tinelli E, Somandin C, Gerber J, Pereira J, et al. Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function. elife. 2019;8: pubmed publisher
Sala D, Ornaghi F, Morena F, Argentati C, Valsecchi M, Alberizzi V, et al. Therapeutic advantages of combined gene/cell therapy strategies in a murine model of GM2 gangliosidosis. Mol Ther Methods Clin Dev. 2022;25:170-189 pubmed publisher
Lee J, Park J, Lee K, Lee D. Clemastine improves electrophysiologic and histomorphometric changes through promoting myelin repair in a murine model of compression neuropathy. Sci Rep. 2021;11:20886 pubmed publisher
Allan K, Hu L, Scavuzzo M, Morton A, Gevorgyan A, Cohn E, et al. Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function. Cell Stem Cell. 2021;28:257-272.e11 pubmed publisher
Reed C, Frick L, Weaver A, Sidoli M, Schlant E, Feltri M, et al. Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury. J Neurosci. 2020;40:6165-6176 pubmed publisher
Mohamed E, Paisley C, Meyer L, Bigbee J, Sato Bigbee C. Endogenous opioid peptides and brain development: Endomorphin-1 and Nociceptin play a sex-specific role in the control of oligodendrocyte maturation and brain myelination. Glia. 2020;68:1513-1530 pubmed publisher
Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez Anido C, et al. Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Hum Mol Genet. 2019;28:1260-1273 pubmed publisher
Clayton B, Huang A, Kunjamma R, Solanki A, Popko B. The integrated stress response in hypoxia-induced diffuse white matter injury. J Neurosci. 2017;: pubmed publisher
Beirowski B, Wong K, Babetto E, Milbrandt J. mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells. Proc Natl Acad Sci U S A. 2017;114:E4261-E4270 pubmed publisher
Shao Z, Lee X, Huang G, Sheng G, Henderson C, Louvard D, et al. LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway. J Neurosci. 2017;37:3127-3137 pubmed publisher
Rolyan H, Tyurina Y, Hernandez M, Amoscato A, Sparvero L, Nmezi B, et al. Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression. J Neurosci. 2015;35:12002-17 pubmed publisher
product information
Product Type :
Antibody
Product Name :
MAG Polyclonal Antibody
Catalog # :
34-6200
Quantity :
100 µg
Price :
US 502
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20°C
Description :
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
Immunogen :
Human S/L-MAG fusion protein with a C-terminal region insert.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
Aliases :
1B236; Brain neuron cytoplasmic protein 3; Gma; MAG; myelin associated glycoprotein; myelin-associated glycoprotein; sialic acid binding Ig-like lectin 4A; sialic acid-binding Ig-like lectin 4a; sialic acid-binding immunoglobulin-like lectin 4A; SIGLEC4A; siglec-4a; S-MAG; S-MAG (C-term.); SPG75
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA