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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
FZR1 Polyclonal Antibody
catalog :
34-2000
quantity :
100 µg
price :
US 428
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunoprecipitation
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1b
Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, et al. Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner. Cell Discov. 2016;2:15044 pubmed publisher
Wang C, Li H, Wu L, Jiao X, Jin Z, Zhu Y, et al. Coiled-Coil Domain-Containing 68 Downregulation Promotes Colorectal Cancer Cell Growth by Inhibiting ITCH-Mediated CDK4 Degradation. Front Oncol. 2021;11:668743 pubmed publisher
Simoneschi D, Róna G, Zhou N, Jeong Y, Jiang S, Milletti G, et al. CRL4AMBRA1 is a master regulator of D-type cyclins. Nature. 2021;592:789-793 pubmed publisher
Tyagi A, Sarodaya N, Kaushal K, Chandrasekaran A, Antao A, Suresh B, et al. E3 Ubiquitin Ligase APC/CCdh1 Regulation of Phenylalanine Hydroxylase Stability and Function. Int J Mol Sci. 2020;21: pubmed publisher
Kaushal K, Woo S, Tyagi A, Kim D, Suresh B, Kim K, et al. E3 Ubiquitin Ligase APC/CCdh1 Negatively Regulates FAH Protein Stability by Promoting Its Polyubiquitination. Int J Mol Sci. 2020;21: pubmed publisher
Wang Z, Dai X, Zhong J, Inuzuka H, Wan L, Li X, et al. SCF(β-TRCP) promotes cell growth by targeting PR-Set7/Set8 for degradation. Nat Commun. 2015;6:10185 pubmed publisher
product information
Product Type :
Antibody
Product Name :
FZR1 Polyclonal Antibody
Catalog # :
34-2000
Quantity :
100 µg
Price :
US 428
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20°C
Description :
FZR is a 7WD domain family member implicated in cell cycle regulation of Drosophila and yeast. It has been shown that the over expression of fzr proteins increases natural killer cell-mediated cell death and as a result, suppresses tumor growth. The fzr protein is essential for cyclosome activity.
Immunogen :
Synthetic peptide derived from the C-terminus of human FZR protein
Format :
Liquid
Applications w/Dilutions :
Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Aliases :
AW108046; CDC20 homolog 1; CDC20C; CDC20-like 1b; CDC20-like protein 1; Cdh1; Cdh1/Hct1 homolog; cell division cycle 20 related 1; fizzy/cell division cycle 20 related 1; fizzy/cell division cycle 20 related 1 (Drosophila); fizzy-related protein homolog; Fyr; FZR; Fzr1; FZR2; HCDH; HCDH1; KIAA1242
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA