delta Catenin Monoclonal Antibody (15D2) | Invitrogen 33-9600 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

delta Catenin Monoclonal Antibody (15D2)

catalog :

33-9600

quantity :

100 µL

price :

US 482

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

15D2

reactivity :

human, mouse, rat, dogs

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:100	Kourtidis A, Yanagisawa M, Huveldt D, Copland J, Anastasiadis P. Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer. PLoS ONE. 2015;10:e0129964 pubmed publisher
immunocytochemistry; mouse; fig 5	Shahbazi M, Megias D, Epifano C, Akhmanova A, Gundersen G, Fuchs E, et al. CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions. J Cell Biol. 2013;203:1043-61 pubmed publisher
immunohistochemistry; human; fig 1 western blot; human; fig 1	Huveldt D, Lewis Tuffin L, Carlson B, Schroeder M, Rodriguez F, Giannini C, et al. Targeting Src family kinases inhibits bevacizumab-induced glioma cell invasion. PLoS ONE. 2013;8:e56505 pubmed publisher
immunocytochemistry; mouse western blot; mouse	Wang Q, Lin J, Chan S, Lin J. The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development. Dev Biol. 2013;374:264-80 pubmed publisher
immunohistochemistry - paraffin section; human; 1:200	Chung Y, Lam A, Luk J, Law S, Chan K, Lee P, et al. Altered E-cadherin expression and p120 catenin localization in esophageal squamous cell carcinoma. Ann Surg Oncol. 2007;14:3260-7 pubmed
immunocytochemistry; mouse; fig 1 western blot; mouse; fig 1	Kim Y, Sauer C, Testa K, Wahl J, Svoboda R, Johnson K, et al. Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex. J Cell Sci. 2005;118:3883-94 pubmed
immunohistochemistry - paraffin section; human; tbl 1	Wheelock M, Soler A, Knudsen K. Cadherin junctions in mammary tumors. J Mammary Gland Biol Neoplasia. 2001;6:275-85 pubmed
	Kourtidis A, Necela B, Lin W, Lu R, Feathers R, Asmann Y, et al. Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling. J Cell Biol. 2017;216:3073-3085 pubmed publisher
	Wang R, Chen Y, Dashwood W, Li Q, LOHR C, Fischer K, et al. Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors. Mol Carcinog. 2017;56:1733-1742 pubmed publisher
	Tille J, Ho L, Shah J, Seyde O, McKee T, Citi S. The Expression of the Zonula Adhaerens Protein PLEKHA7 Is Strongly Decreased in High Grade Ductal and Lobular Breast Carcinomas. PLoS ONE. 2015;10:e0135442 pubmed publisher
	Christensen H, Trotter C, Hickman M, Edmunds W. Re-evaluating cost effectiveness of universal meningitis vaccination (Bexsero) in England: modelling study. BMJ. 2014;349:g5725 pubmed publisher
	Epifano C, Megias D, Perez Moreno M. p120-catenin differentially regulates cell migration by Rho-dependent intracellular and secreted signals. EMBO Rep. 2014;15:592-600 pubmed publisher
	Lewis Tuffin L, Rodriguez F, Giannini C, Scheithauer B, Necela B, Sarkaria J, et al. Misregulated E-cadherin expression associated with an aggressive brain tumor phenotype. PLoS ONE. 2010;5:e13665 pubmed publisher
	Tinkle C, Lechler T, Pasolli H, Fuchs E. Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses. Proc Natl Acad Sci U S A. 2004;101:552-7 pubmed
	Humtsoe J, Feng S, Thakker G, Yang J, Hong J, Wary K. Regulation of cell-cell interactions by phosphatidic acid phosphatase 2b/VCIP. EMBO J. 2003;22:1539-54 pubmed

product information

Product Type :

Antibody

Product Name :

delta Catenin Monoclonal Antibody (15D2)

Catalog # :

33-9600

Quantity :

100 µL

Pricing :

US 482

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Canine, Human, Mouse, Rat

Applications :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:500

Species :

Canine, Human, Mouse, Rat

Clone :

15D2

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.

Immunogen :

Recombinant fusion protein derived from the C-terminus of murine p120ct

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:500

Aliases :

AA409437; AU019353; cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin associated protein), delta 1; catenin (cadherin-associated protein), delta 1; catenin delta 1; catenin delta-1; catenin src; catenin, delta 1; Catns; CTNND; Ctnnd1; hypothetical protein; Kiaa0384; mKIAA0384; p120; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(CAS); p120(ctn); P120CAS; p120-catenin; P120CTN

more info or order :

Invitrogen product webpage