SRSF3 Monoclonal Antibody (1H4G7) | Invitrogen 33-9400 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SRSF3 Monoclonal Antibody (1H4G7)

catalog :

33-9400

quantity :

100 µg

price :

US 428

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1H4G7

reactivity :

hamsters, human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; human	Erkelenz S, Hillebrand F, Widera M, Theiss S, Fayyaz A, Degrandi D, et al. Balanced splicing at the Tat-specific HIV-1 3'ss A3 is critical for HIV-1 replication. Retrovirology. 2015;12:29 pubmed publisher
western blot; human; 1:5000; fig 6	Wong R, Balachandran A, Ostrowski M, Cochrane A. Digoxin suppresses HIV-1 replication by altering viral RNA processing. PLoS Pathog. 2013;9:e1003241 pubmed publisher
chromatin immunoprecipitation; mouse; fig 1 western blot; mouse; fig 1	Walsh C, Suchanek A, Cyphert T, Kohan A, Szeszel Fedorowicz W, Salati L. Serine arginine splicing factor 3 is involved in enhanced splicing of glucose-6-phosphate dehydrogenase RNA in response to nutrients and hormones in liver. J Biol Chem. 2013;288:2816-28 pubmed publisher
immunohistochemistry; mouse; 1:100; fig 3 western blot; mouse; 1:100; fig 3 immunohistochemistry; human; 1:100; fig 3 western blot; human; 1:100; fig 3	Toiber D, Azkona G, Ben Ari S, Toran N, Soreq H, Dierssen M. Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations. Neurobiol Dis. 2010;40:348-59 pubmed publisher
western blot; hamsters	Meerson A, Cacheaux L, Goosens K, Sapolsky R, Soreq H, Kaufer D. Changes in brain MicroRNAs contribute to cholinergic stress reactions. J Mol Neurosci. 2010;40:47-55 pubmed publisher
	Ajiro M, Awaya T, Kim Y, Iida K, Denawa M, Tanaka N, et al. Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia. Nat Commun. 2021;12:4507 pubmed publisher
	Kováčová T, Soucek P, Hujová P, Freiberger T, Grodecka L. Splicing Enhancers at Intron-Exon Borders Participate in Acceptor Splice Sites Recognition. Int J Mol Sci. 2020;21: pubmed publisher
	Iwai K, Yaguchi M, Nishimura K, Yamamoto Y, Tamura T, Nakata D, et al. Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability. EMBO Mol Med. 2018;10: pubmed publisher
	Anderson E, Lin C, Xiao X, Stoilov P, Burge C, Black D. The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B. RNA. 2012;18:1041-9 pubmed publisher
	Glanzer J, Miyashiro K, Sul J, Barrett L, Belt B, Haydon P, et al. RNA splicing capability of live neuronal dendrites. Proc Natl Acad Sci U S A. 2005;102:16859-64 pubmed
	Buratti E, Muro A, Giombi M, Gherbassi D, Iaconcig A, Baralle F. RNA folding affects the recruitment of SR proteins by mouse and human polypurinic enhancer elements in the fibronectin EDA exon. Mol Cell Biol. 2004;24:1387-400 pubmed
	Dickinson L, Edgar A, Ehley J, Gottesfeld J. Cyclin L is an RS domain protein involved in pre-mRNA splicing. J Biol Chem. 2002;277:25465-73 pubmed

product information

Product Type :

Antibody

Product Name :

SRSF3 Monoclonal Antibody (1H4G7)

Catalog # :

33-9400

Quantity :

100 µg

Pricing :

US 428

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Xenopus laevis

Applications :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent

Species :

Human, Xenopus laevis

Clone :

1H4G7

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

SR proteins appear to be recruited from nuclear "speckles", in which they are concentrated, to sites of transcription in order to spatially coordinate transcription and pre-mRNA splicing within the cell nucleus.

Immunogen :

Mass-isolated nuclei from Xenopus Laevis oocytes.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent

Aliases :

AL024116; pre-mRNA splicing factor SRp20; pre-mRNA-splicing factor SRP20; Protein X16; serine and arginine rich splicing factor 3; serine/arginine-rich splicing factor 3; SFRS3; splicing factor, arginine/serine-rich 3; splicing factor, arginine/serine-rich 3 (SRp20); splicing factor, arginine/serine-rich, 20-kD; Srp20; SRSF3; X16

more info or order :

Invitrogen product webpage