product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ZO-1 Monoclonal Antibody (ZO1-1A12)
catalog :
33-9100
quantity :
100µg
price :
US 344.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
ZO1-1A12
reactivity :
guinea pig, turquoise killifish, Burton's mouthbrooder, Japanese rice fish, African green monkey, goldfish, Trachemys dorbigni, human, mouse, rat, dogs, chicken, bovine, pigs , zebrafish , cat, domestic sheep, Xenopus laevis, domestic rabbit, rhesus macaque
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section, other, western blot knockout validation
more info or order :
Invitrogen product webpage
citations: 562
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; rat; loading ...; fig 4d
  • immunocytochemistry; rat; loading ...; fig 5
Van Itallie C, Tietgens A, Anderson J. Visualizing the dynamic coupling of claudin strands to the actin cytoskeleton through ZO-1. Mol Biol Cell. 2017;28:524-534 pubmed publisher
  • immunohistochemistry; turquoise killifish; loading ...; fig s2f
Coolen M, Labusch M, Mannioui A, Bally Cuif L. Mosaic Heterochrony in Neural Progenitors Sustains Accelerated Brain Growth and Neurogenesis in the Juvenile Killifish N. furzeri. Curr Biol. 2020;30:736-745.e4 pubmed publisher
  • other; zebrafish ; 1:100; loading ...
Wangen J, Green R. Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides. elife. 2020;9: pubmed publisher
  • other; zebrafish ; 1:100; loading ...
Arora P, Dongre S, Raman R, Sonawane M. Stepwise polarisation of developing bilayered epidermis is mediated by aPKC and E-cadherin in zebrafish. elife. 2020;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 5b
Findlay A, McKie L, Keighren M, Clementson Mobbs S, Sanchez Pulido L, Wells S, et al. Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function. Sci Rep. 2020;10:437 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:200; loading ...; fig 7b3
Thouvenin O, Keiser L, Cantaut Belarif Y, Carbó Tano M, Verweij F, Jurisch Yaksi N, et al. Origin and role of the cerebrospinal fluid bidirectional flow in the central canal. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; 1:2000; loading ...; fig 5d
Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 6g
Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1e
Luong P, Hedl M, Yan J, Zuo T, Fu T, Jiang X, et al. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. elife. 2018;7: pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig s2c
  • immunocytochemistry; dogs; 1:1000; fig s4b
Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed publisher
  • immunohistochemistry; rat; 1:500; loading ...; fig 2
Liang F, Hwang J, Tang N, Hunziker W. Juxtanodin in retinal pigment epithelial cells: Expression and biological activities in regulating cell morphology and actin cytoskeleton organization. J Comp Neurol. 2018;526:205-215 pubmed publisher
  • western blot; mouse; 1:400; loading ...; fig 4f, 4h
Boussadia B, Lakhal L, Payrastre L, Ghosh C, Pascussi J, Gangarossa G, et al. Pregnane X Receptor Deletion Modifies Recognition Memory and Electroencephalographic Activity. Neuroscience. 2018;370:130-138 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1f
Pelz L, Purfürst B, Rathjen F. The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice. J Biol Chem. 2017;292:21490-21503 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2 - s1b
Connell M, Chen H, Jiang J, Kuan C, Fotovati A, Chu T, et al. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. elife. 2017;6: pubmed publisher
  • western blot; human; loading ...; fig 4c
Li P, Wang Y, Mao X, Jiang Y, Liu J, Li J, et al. CRB3 downregulation confers breast cancer stem cell traits through TAZ/?-catenin. Oncogenesis. 2017;6:e322 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1g
Kharfallah F, Guyot M, El Hassan A, Allache R, Merello E, De Marco P, et al. Scribble1 plays an important role in the pathogenesis of neural tube defects through its mediating effect of Par-3 and Vangl1/2 localization. Hum Mol Genet. 2017;26:2307-2320 pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig s1a, s1e
Ahmed S, Macara I. The Par3 polarity protein is an exocyst receptor essential for mammary cell survival. Nat Commun. 2017;8:14867 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:200; loading ...; fig 3c
Xavier A, Fontaine R, Bloch S, Affaticati P, Jenett A, Demarque M, et al. Comparative analysis of monoaminergic cerebrospinal fluid-contacting cells in Osteichthyes (bony vertebrates). J Comp Neurol. 2017;525:2265-2283 pubmed publisher
  • immunohistochemistry; human; 1:200; fig 5A
Geng Z, Walsh P, Truong V, Hill C, Ebeling M, Kapphahn R, et al. Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. PLoS ONE. 2017;12:e0173575 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...
Zhang W, Li H, Ogando D, Li S, Feng M, Price F, et al. Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium. EBioMedicine. 2017;16:292-301 pubmed publisher
  • immunohistochemistry; rat; 1:100; loading ...; fig 1
  • western blot; rat; 1:250; loading ...; fig 2a
Dukic A, Haugen L, Pidoux G, Leithe E, Bakke O, Tasken K. A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells. Cell Signal. 2017;32:1-11 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1a
  • immunohistochemistry; human; loading ...; fig 6a
  • western blot; human; loading ...; fig 1a
Lesage J, Suarez Carmona M, Neyrinck Leglantier D, Grelet S, Blacher S, Hunziker W, et al. Zonula occludens-1/NF-?B/CXCL8: a new regulatory axis for tumor angiogenesis. FASEB J. 2017;31:1678-1688 pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; fig 1a
Priya R, Liang X, Teo J, Duszyc K, Yap A, Gomez G. ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. Mol Biol Cell. 2017;28:12-20 pubmed publisher
  • immunohistochemistry; human; 1:200; loading ...; fig 2b
Wang M, Nagle R, Knudsen B, Rogers G, Cress A. A basal cell defect promotes budding of prostatic intraepithelial neoplasia. J Cell Sci. 2017;130:104-110 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 2
Shadforth A, Suzuki S, Theodoropoulos C, Richardson N, Chirila T, Harkin D. A Bruch's membrane substitute fabricated from silk fibroin supports the function of retinal pigment epithelial cells in vitro. J Tissue Eng Regen Med. 2017;11:1915-1924 pubmed publisher
  • immunohistochemistry; domestic rabbit; fig 4
  • western blot; domestic rabbit; fig 3
Kageyama T, Hayashi R, Hara S, Yoshikawa K, Ishikawa Y, Yamato M, et al. Spontaneous acquisition of infinite proliferative capacity by a rabbit corneal endothelial cell line with maintenance of phenotypic and physiological characteristics. J Tissue Eng Regen Med. 2017;11:1057-1064 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3d
Yuan J, Cha J, Deng W, Bartos A, Sun X, Ho H, et al. Planar cell polarity signaling in the uterus directs appropriate positioning of the crypt for embryo implantation. Proc Natl Acad Sci U S A. 2016;113:E8079-E8088 pubmed
  • western blot; human; 1:1000; loading ...; fig 2a
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6e
  • western blot; mouse; 1:1000; loading ...; fig 6a
Lin Z, Zhang Y, Xia Y, Xu X, Jiao X, Sun J. Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway. J Biol Chem. 2016;291:26837-26849 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 6d
Wufuer M, Lee G, Hur W, Jeon B, Kim B, Choi T, et al. Skin-on-a-chip model simulating inflammation, edema and drug-based treatment. Sci Rep. 2016;6:37471 pubmed publisher
  • immunohistochemistry; mouse; 1:300; loading ...; tbl 1
Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed publisher
  • immunohistochemistry; zebrafish ; 1:150; fig s5a
Kantarci H, Gerberding A, Riley B. Spemann organizer gene Goosecoid promotes delamination of neuroblasts from the otic vesicle. Proc Natl Acad Sci U S A. 2016;113:E6840-E6848 pubmed
  • immunohistochemistry - paraffin section; zebrafish ; 1:100; loading ...; fig 4a
Cronan M, Beerman R, ROSENBERG A, Saelens J, Johnson M, Oehlers S, et al. Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection. Immunity. 2016;45:861-876 pubmed publisher
  • immunocytochemistry; human; 1:100; tbl 2
Kilic O, Pamies D, Lavell E, Schiapparelli P, Feng Y, Hartung T, et al. Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis. Lab Chip. 2016;16:4152-4162 pubmed
  • immunohistochemistry - paraffin section; human; 1:100; fig s2
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 4
Neckel P, Mattheus U, Hirt B, Just L, Mack A. Large-scale tissue clearing (PACT): Technical evaluation and new perspectives in immunofluorescence, histology, and ultrastructure. Sci Rep. 2016;6:34331 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5h
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig s10h
Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, et al. Frizzled proteins are colonic epithelial receptors for C. difficile toxin B. Nature. 2016;538:350-355 pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; fig 5c
Priya R, Wee K, Budnar S, Gomez G, Yap A, Michael M. Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II. Cell Cycle. 2016;15:3033-3041 pubmed
  • immunocytochemistry; human; fig 2a
Gallego Delgado J, Basu Roy U, Ty M, Alique M, Fernandez Arias C, Movila A, et al. Angiotensin receptors and ?-catenin regulate brain endothelial integrity in malaria. J Clin Invest. 2016;126:4016-4029 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1d
  • western blot; human; 1:1000; loading ...; fig 5a
Kuan W, Bennett N, He X, Skepper J, Martynyuk N, Wijeyekoon R, et al. ?-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function. Exp Neurol. 2016;285:72-81 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 3a
Coburn L, Lopez H, Caldwell B, Moussa E, Yap C, Priya R, et al. Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates. Mol Biol Cell. 2016;27:3436-3448 pubmed
  • immunohistochemistry - paraffin section; human; fig 1
  • western blot; human; fig 1
Yuki T, Tobiishi M, Kusaka Kikushima A, Ota Y, Tokura Y. Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17. PLoS ONE. 2016;11:e0161759 pubmed publisher
  • immunocytochemistry; human; fig s2
  • western blot; human; fig s1
Huang L, Stuart C, Takeda K, D Agnillo F, Golding B. Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5. PLoS ONE. 2016;11:e0160875 pubmed publisher
  • immunocytochemistry; dogs; 1:200; fig 5
  • western blot; dogs; 1:1000; fig 3a
Ronaghan N, Shang J, Iablokov V, Zaheer R, Colarusso P, Dion S, et al. The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction. Am J Physiol Gastrointest Liver Physiol. 2016;311:G466-79 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig s3
Reginensi A, Enderle L, Gregorieff A, Johnson R, Wrana J, McNeill H. A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nat Commun. 2016;7:12309 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1e
  • immunocytochemistry; human; fig 2c
  • western blot; human; 1:4000; fig 3a
Babkair H, Yamazaki M, Uddin M, Maruyama S, Abe T, Essa A, et al. Aberrant expression of the tight junction molecules claudin-1 and zonula occludens-1 mediates cell growth and invasion in oral squamous cell carcinoma. Hum Pathol. 2016;57:51-60 pubmed publisher
  • immunohistochemistry; mouse; fig s6
Grahammer F, Wigge C, Schell C, Kretz O, Patrakka J, Schneider S, et al. A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes. JCI Insight. 2016;1: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3o
Pollock L, Gupta N, Chen X, Luna E, McDermott B. Supervillin Is a Component of the Hair Cell's Cuticular Plate and the Head Plates of Organ of Corti Supporting Cells. PLoS ONE. 2016;11:e0158349 pubmed publisher
  • immunohistochemistry; human; fig 4
He Z, Forest F, Gain P, Rageade D, Bernard A, Acquart S, et al. 3D map of the human corneal endothelial cell. Sci Rep. 2016;6:29047 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4
Folmsbee S, Wilcox D, Tyberghein K, De Bleser P, Tourtellotte W, van Hengel J, et al. ?T-catenin in restricted brain cell types and its potential connection to autism. J Mol Psychiatry. 2016;4:2 pubmed publisher
  • immunocytochemistry; human; 10 ug/ml; fig 1
Booth J, Duggan E, Patel V, Langer M, Wu W, Braun A, et al. Bacillus anthracis spore movement does not require a carrier cell and is not affected by lethal toxin in human lung models. Microbes Infect. 2016;18:615-626 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 3a
Li Q, Sodroski C, Lowey B, Schweitzer C, Cha H, Zhang F, et al. Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition. Proc Natl Acad Sci U S A. 2016;113:7620-5 pubmed publisher
  • immunocytochemistry; mouse; fig 5
  • flow cytometry; human; fig 3
  • immunocytochemistry; human; fig 3
Du C, Narayanan K, Leong M, Ibrahim M, Chua Y, Khoo V, et al. Functional Kidney Bioengineering with Pluripotent Stem-Cell-Derived Renal Progenitor Cells and Decellularized Kidney Scaffolds. Adv Healthc Mater. 2016;5:2080-91 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 8b
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez Carballo A, Gutierrez Uzquiza A, et al. C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38? activation, while it impairs tumor growth through p38?-independent mechanisms. Oncotarget. 2016;7:45060-45078 pubmed publisher
  • immunohistochemistry - frozen section; zebrafish ; 1:200; fig 2
Hudish L, Galati D, Ravanelli A, Pearson C, Huang P, Appel B. miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling. Development. 2016;143:2292-304 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 4
Santos A, Durkin C, Helaine S, Boucrot E, Holden D. Clustered Intracellular Salmonella enterica Serovar Typhimurium Blocks Host Cell Cytokinesis. Infect Immun. 2016;84:2149-2158 pubmed publisher
  • western blot; human; fig 6
Teo W, Merino V, Cho S, Korangath P, Liang X, Wu R, et al. HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24. Oncogene. 2016;35:5539-5551 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 1
Takeo Y, Kurabayashi N, Nguyen M, Sanada K. The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway. Sci Rep. 2016;6:25180 pubmed publisher
  • immunocytochemistry; human; 1:50; fig 2
Zoschke C, Ulrich M, Sochorová M, Wolff C, Vavrova K, Ma N, et al. The barrier function of organotypic non-melanoma skin cancer models. J Control Release. 2016;233:10-8 pubmed publisher
  • immunocytochemistry; pigs ; 1:50; fig 3
Di Lauro S, Rodriguez Crespo D, Gayoso M, Garcia Gutierrez M, Pastor J, Srivastava G, et al. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Mol Vis. 2016;22:243-53 pubmed
  • immunocytochemistry; mouse; 1:250; fig 4
Martovetsky G, Bush K, Nigam S. Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers. Drug Metab Dispos. 2016;44:1050-60 pubmed publisher
  • immunohistochemistry - free floating section; zebrafish ; 1:200; fig 7
Sepich D, Solnica Krezel L. Intracellular Golgi Complex organization reveals tissue specific polarity during zebrafish embryogenesis. Dev Dyn. 2016;245:678-91 pubmed publisher
  • immunocytochemistry; pigs ; 1:100; fig 3
Kwon J, Jeong S, Choi I, Kim N. ADAM10 Is Involved in Cell Junction Assembly in Early Porcine Embryo Development. PLoS ONE. 2016;11:e0152921 pubmed publisher
  • immunocytochemistry; human; 1:500; fig s1
Lee N, Fok K, White A, Wilson N, O Leary C, Cox H, et al. Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. Nat Commun. 2016;7:11082 pubmed publisher
  • immunocytochemistry; human; 1:50; fig s2f
Djuric I, Siebrasse J, Schulze U, Granado D, Schlüter M, Kubitscheck U, et al. The C-terminal domain controls the mobility of Crumbs 3 isoforms. Biochim Biophys Acta. 2016;1863:1208-17 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4
Ichise H, Ichise T, Yoshida N. Phospholipase Cγ2 Is Required for Luminal Expansion of the Epididymal Duct during Postnatal Development in Mice. PLoS ONE. 2016;11:e0150521 pubmed publisher
  • immunohistochemistry; human; 1:200; fig s1
Dora K, Stanley C, Al Jaaly E, Fiorentino F, Ascione R, Reeves B, et al. Isolated Human Pulmonary Artery Structure and Function Pre- and Post-Cardiopulmonary Bypass Surgery. J Am Heart Assoc. 2016;5: pubmed publisher
  • immunocytochemistry; rat; 1:100; fig 3
Raredon M, Ghaedi M, Calle E, Niklason L. A Rotating Bioreactor for Scalable Culture and Differentiation of Respiratory Epithelium. Cell Med. 2015;7:109-21 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 1
Wiltshire R, Nelson V, Kho D, Angel C, O Carroll S, Graham E. Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors. Sci Rep. 2016;6:19814 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 4
Grego Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson K. The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. elife. 2016;5:e12034 pubmed publisher
  • immunocytochemistry; human; fig 2
Forest F, Thuret G, Gain P, Dumollard J, Peoc h M, Perrache C, et al. Optimization of immunostaining on flat-mounted human corneas. Mol Vis. 2015;21:1345-56 pubmed
  • western blot; dogs; 1:2000; fig 1
Tien S, Lee H, Yang Y, Lin M, Chen Y, Chang Z. The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42. Nat Commun. 2016;7:10420 pubmed publisher
  • immunocytochemistry; mouse; fig 2
Kitayama M, Mizutani K, Maruoka M, Mandai K, Sakakibara S, Ueda Y, et al. A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development. J Biol Chem. 2016;291:5817-31 pubmed publisher
  • immunocytochemistry; rat; 1:200; fig 8
Yang S, Krug S, Heitmann J, Hu L, Reinhold A, Sauer S, et al. Analgesic drug delivery via recombinant tissue plasminogen activator and microRNA-183-triggered opening of the blood-nerve barrier. Biomaterials. 2016;82:20-33 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 4
  • western blot; mouse; fig 4
Zhang Y, Fan J, Ho J, Hu T, Kneeland S, Fan X, et al. Crim1 regulates integrin signaling in murine lens development. Development. 2016;143:356-66 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4d
  • western blot; mouse; 1:2000; loading ...; fig 4b
Shi Y, Liu T, Fu J, Xu W, Wu L, Hou A, et al. Vitamin D/VDR signaling attenuates lipopolysaccharide‑induced acute lung injury by maintaining the integrity of the pulmonary epithelial barrier. Mol Med Rep. 2016;13:1186-94 pubmed publisher
  • immunohistochemistry - free floating section; mouse; fig 2
Stefanitsch C, Lawrence A, Olverling A, Nilsson I, Fredriksson L. tPA Deficiency in Mice Leads to Rearrangement in the Cerebrovascular Tree and Cerebroventricular Malformations. Front Cell Neurosci. 2015;9:456 pubmed publisher
  • immunocytochemistry; mouse; fig 5e
Yoshie S, Imaizumi M, Nakamura R, Otsuki K, Ikeda M, Nomoto Y, et al. Generation of airway epithelial cells with native characteristics from mouse induced pluripotent stem cells. Cell Tissue Res. 2016;364:319-30 pubmed publisher
  • western blot; dogs; fig 1c
Shukla P, Vogl C, Wallner B, Rigler D, Müller M, Macho Maschler S. High-throughput mRNA and miRNA profiling of epithelial-mesenchymal transition in MDCK cells. BMC Genomics. 2015;16:944 pubmed publisher
  • immunocytochemistry; human; fig 1
Dixon D, Coates J, Del Carpio Pons A, Horabin J, Walker A, Abdul N, et al. A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty. Sci Rep. 2015;5:16466 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 1
Freedman B, Brooks C, Lam A, Fu H, Morizane R, Agrawal V, et al. Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids. Nat Commun. 2015;6:8715 pubmed publisher
  • western blot; human
Fujimura K, Choi S, Wyse M, Strnadel J, Wright T, Klemke R. Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels. J Biol Chem. 2015;290:29907-19 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:300
Abu Siniyeh A, Owen D, Benzing C, Rinkwitz S, Becker T, Majumdar A, et al. The aPKC/Par3/Par6 Polarity Complex and Membrane Order Are Functionally Interdependent in Epithelia During Vertebrate Organogenesis. Traffic. 2016;17:66-79 pubmed publisher
  • immunohistochemistry; mouse
Arya P, Rainey M, Bhattacharyya S, Mohapatra B, George M, Kuracha M, et al. The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015;408:41-55 pubmed publisher
  • immunocytochemistry; dogs; fig 2
  • immunocytochemistry; human; fig 2
Barrows D, Schoenfeld S, Hodakoski C, Silkov A, Honig B, Couvillon A, et al. p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase. J Biol Chem. 2015;290:28915-31 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig s1
Bruurs L, Donker L, Zwakenberg S, Zwartkruis F, Begthel H, Knisely A, et al. ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization. J Cell Biol. 2015;210:1055-63 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 7
Liu R, Yang Y, Shen J, Chen H, Zhang Q, Ba R, et al. Fstl1 is involved in the regulation of radial glial scaffold development. Mol Brain. 2015;8:53 pubmed publisher
  • immunocytochemistry; human; 1:300; fig s1g
Priya R, Gomez G, Budnar S, Verma S, Cox H, Hamilton N, et al. Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nat Cell Biol. 2015;17:1282-93 pubmed publisher
  • immunocytochemistry; human; fig 4
Thuringer D, Berthenet K, Cronier L, Solary E, Garrido C. Primary tumor- and metastasis-derived colon cancer cells differently modulate connexin expression and function in human capillary endothelial cells. Oncotarget. 2015;6:28800-15 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig s3
Baruch K, Rosenzweig N, Kertser A, Deczkowska A, Sharif A, Spinrad A, et al. Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology. Nat Commun. 2015;6:7967 pubmed publisher
  • immunohistochemistry - paraffin section; human; 10 ug/ml
  • immunocytochemistry; human; 1.25 ug/ml
  • western blot; human; 1 ug/ml
Smith N, Hinley J, Varley C, Eardley I, Trejdosiewicz L, Southgate J. The human urothelial tight junction: claudin 3 and the ZO-1α+ switch. Bladder (San Franc). 2015;2:e9 pubmed
  • western blot; human; 1:300; fig 4
Kontro H, Cannino G, Rustin P, Dufour E, Kainulainen H. DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells. PLoS ONE. 2015;10:e0131990 pubmed publisher
  • immunocytochemistry; human; 1:500; fig s4
O Carroll S, Kho D, Wiltshire R, Nelson V, Rotimi O, Johnson R, et al. Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells. J Neuroinflammation. 2015;12:131 pubmed publisher
  • immunocytochemistry; mouse; 1:100
Maggiorani D, Dissard R, Belloy M, Saulnier Blache J, Casemayou A, Ducassé L, et al. Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells. PLoS ONE. 2015;10:e0131416 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5
Sugiyama Y, Shelley E, Badouel C, McNeill H, McAvoy J. Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation. Invest Ophthalmol Vis Sci. 2015;56:4099-107 pubmed publisher
  • immunohistochemistry; mouse; 1:50; fig 4
Preuße K, Tveriakhina L, Schuster Gossler K, Gaspar C, Rosa A, Henrique D, et al. Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo. PLoS Genet. 2015;11:e1005328 pubmed publisher
  • immunocytochemistry; human; 5 ug/ml
Krivega M, Essahib W, Van de Velde H. WNT3 and membrane-associated β-catenin regulate trophectoderm lineage differentiation in human blastocysts. Mol Hum Reprod. 2015;21:711-22 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Schell C, Kretz O, Bregenzer A, Rogg M, Helmstädter M, Lisewski U, et al. Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response. PLoS ONE. 2015;10:e0129424 pubmed publisher
  • immunocytochemistry; human; 1:100
Vainio I, Abu Khamidakh A, Paci M, Skottman H, Juuti Uusitalo K, Hyttinen J, et al. Computational Model of Ca2+ Wave Propagation in Human Retinal Pigment Epithelial ARPE-19 Cells. PLoS ONE. 2015;10:e0128434 pubmed publisher
  • immunocytochemistry; rat
Overgaard C, Schlingmann B, Dorsainvil White S, Ward C, Fan X, Swarnakar S, et al. The relative balance of GM-CSF and TGF-β1 regulates lung epithelial barrier function. Am J Physiol Lung Cell Mol Physiol. 2015;308:L1212-23 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 1
Karbalaie K, Tanhaei S, Rabiei F, Kiani Esfahani A, Masoudi N, Nasr Esfahani M, et al. Stem cells from human exfoliated deciduous tooth exhibit stromal-derived inducing activity and lead to generation of neural crest cells from human embryonic stem cells. Cell J. 2015;17:37-48 pubmed
  • western blot; mouse
Wu S, Yi J, Zhang Y, Zhou J, Sun J. Leaky intestine and impaired microbiome in an amyotrophic lateral sclerosis mouse model. Physiol Rep. 2015;3: pubmed publisher
  • immunohistochemistry; rat
Ward C, Schlingmann B, Stecenko A, Guidot D, Koval M. NF-κB inhibitors impair lung epithelial tight junctions in the absence of inflammation. Tissue Barriers. 2015;3:e982424 pubmed publisher
  • western blot; mouse; 1:1000
Muramatsu R, Kuroda M, Matoba K, Lin H, Takahashi C, Koyama Y, et al. Prostacyclin prevents pericyte loss and demyelination induced by lysophosphatidylcholine in the central nervous system. J Biol Chem. 2015;290:11515-25 pubmed publisher
  • western blot; mouse; 1:500
Boulay A, Mazeraud A, Cisternino S, Saubaméa B, Mailly P, Jourdren L, et al. Immune quiescence of the brain is set by astroglial connexin 43. J Neurosci. 2015;35:4427-39 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Sohet F, Lin C, Munji R, Lee S, Ruderisch N, Soung A, et al. LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation. J Cell Biol. 2015;208:703-11 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 1
Grego Bessa J, Hildebrand J, Anderson K. Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development. 2015;142:1305-14 pubmed publisher
  • western blot; human
Wu J, Peng D, Zhang Y, Lu Z, Voehler M, Sanders C, et al. Biophysical characterization of interactions between the C-termini of peripheral nerve claudins and the PDZ₁ domain of zonula occludens. Biochem Biophys Res Commun. 2015;459:87-93 pubmed publisher
  • western blot; human; fig 6
Momeny M, Saunus J, Marturana F, McCart Reed A, Black D, Sala G, et al. Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget. 2015;6:3932-46 pubmed
  • western blot; human; 1:100
Wong A, Chin S, Xia S, Garner J, Bear C, Rossant J. Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells. Nat Protoc. 2015;10:363-81 pubmed publisher
  • immunohistochemistry; mouse
Khairallah H, El Andalousi J, Simard A, Haddad N, Chen Y, Hou J, et al. Claudin-7, -16, and -19 during mouse kidney development. Tissue Barriers. 2014;2:e964547 pubmed publisher
  • immunocytochemistry; human; 1:100
Ilina P, Partti S, Niklander J, Ruponen M, Lou Y, Yliperttula M. Effect of differentiation on endocytic profiles of endothelial and epithelial cell culture models. Exp Cell Res. 2015;332:89-101 pubmed publisher
  • immunohistochemistry; guinea pig
Lee S, Kwon J, Choi I, Kim N. Expression and function of transcription factor AP-2? in early embryonic development of porcine parthenotes. Reprod Fertil Dev. 2015;: pubmed publisher
  • immunohistochemistry; human; 1:150
Pienaar I, Lee C, Elson J, McGuinness L, Gentleman S, Kalaria R, et al. Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease. Neurobiol Dis. 2015;74:392-405 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Nacer A, Movila A, Sohet F, Girgis N, Gundra U, Loke P, et al. Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier. PLoS Pathog. 2014;10:e1004528 pubmed publisher
  • immunohistochemistry - frozen section; human
Raiko L, Leinonen P, Hägg P, Peltonen J, Oikarinen A, Peltonen S. Tight junctions in Hailey-Hailey and Darier's diseases. Dermatol Reports. 2009;1:e1 pubmed publisher
  • immunocytochemistry; mouse; fig 2
Chang K, Zollinger D, Susuki K, Sherman D, Makara M, Brophy P, et al. Glial ankyrins facilitate paranodal axoglial junction assembly. Nat Neurosci. 2014;17:1673-81 pubmed publisher
  • immunocytochemistry; human
Mooren O, Li J, Nawas J, Cooper J. Endothelial cells use dynamic actin to facilitate lymphocyte transendothelial migration and maintain the monolayer barrier. Mol Biol Cell. 2014;25:4115-29 pubmed publisher
  • immunohistochemistry - frozen section; mouse
DiTommaso T, Cottle D, Pearson H, Schlüter H, Kaur P, Humbert P, et al. Keratin 76 is required for tight junction function and maintenance of the skin barrier. PLoS Genet. 2014;10:e1004706 pubmed publisher
  • immunohistochemistry; mouse; fig 2
Gegg M, Böttcher A, Burtscher I, Hasenoeder S, Van Campenhout C, Aichler M, et al. Flattop regulates basal body docking and positioning in mono- and multiciliated cells. elife. 2014;3: pubmed publisher
  • flow cytometry; human
Landy J, Al Hassi H, Ronde E, English N, Mann E, Bernardo D, et al. Innate immune factors in the development and maintenance of pouchitis. Inflamm Bowel Dis. 2014;20:1942-9 pubmed publisher
  • immunohistochemistry - paraffin section; rhesus macaque; 1:200
Gumber S, Nusrat A, Villinger F. Immunohistological characterization of intercellular junction proteins in rhesus macaque intestine. Exp Toxicol Pathol. 2014;66:437-44 pubmed publisher
  • immunohistochemistry; human; 5 ug/ml
Krivega M, Geens M, Van de Velde H. CAR expression in human embryos and hESC illustrates its role in pluripotency and tight junctions. Reproduction. 2014;148:531-44 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:200
Yao C, Vanderpool K, Delfiner M, Eddy V, Lucaci A, Soto Riveros C, et al. Electrical synaptic transmission in developing zebrafish: properties and molecular composition of gap junctions at a central auditory synapse. J Neurophysiol. 2014;112:2102-13 pubmed publisher
  • immunohistochemistry; Xenopus laevis; 1:100; fig 6
Sojka S, Amin N, Gibbs D, Christine K, Charpentier M, Conlon F. Congenital heart disease protein 5 associates with CASZ1 to maintain myocardial tissue integrity. Development. 2014;141:3040-9 pubmed publisher
  • western blot; dogs
Spadaro D, Tapia R, Jond L, Sudol M, Fanning A, Citi S. ZO proteins redundantly regulate the transcription factor DbpA/ZONAB. J Biol Chem. 2014;289:22500-11 pubmed publisher
  • immunocytochemistry; human; fig 3
McEwen A, Maher M, Mo R, Gottardi C. E-cadherin phosphorylation occurs during its biosynthesis to promote its cell surface stability and adhesion. Mol Biol Cell. 2014;25:2365-74 pubmed publisher
  • immunohistochemistry; human
Boehlke C, Hartleben B, Huber T, Hopfer H, Walz G, Neumann Haefelin E. Hantavirus infection with severe proteinuria and podocyte foot-process effacement. Am J Kidney Dis. 2014;64:452-6 pubmed publisher
  • immunocytochemistry; dogs; 1:100; fig 4
  • immunocytochemistry; human; 1:100; fig 4
Glotfelty L, Zahs A, Hodges K, Shan K, Alto N, Hecht G. Enteropathogenic E. coli effectors EspG1/G2 disrupt microtubules, contribute to tight junction perturbation and inhibit restoration. Cell Microbiol. 2014;16:1767-83 pubmed publisher
  • immunohistochemistry; chicken; 1:200; fig 5
  • western blot; chicken; 1:1000; fig 5
Herrera A, Saade M, Menendez A, Marti E, Pons S. Sustained Wnt/?-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole. Nat Commun. 2014;5:4168 pubmed publisher
  • western blot; human; 1:200
Price D, Ackland M, Burks W, Knight M, Suphioglu C. Peanut allergens alter intestinal barrier permeability and tight junction localisation in Caco-2 cell cultures. Cell Physiol Biochem. 2014;33:1758-77 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Fallier Becker P, Vollmer J, Bauer H, Noell S, Wolburg H, Mack A. Onset of aquaporin-4 expression in the developing mouse brain. Int J Dev Neurosci. 2014;36:81-9 pubmed publisher
  • immunocytochemistry; dogs; 1:400
Enjoji S, Ohama T, Sato K. Regulation of epithelial cell tight junctions by protease-activated receptor 2. J Vet Med Sci. 2014;76:1225-9 pubmed
  • immunocytochemistry; human; fig 5
Mashukova A, Kozhekbaeva Z, Forteza R, Dulam V, Figueroa Y, Warren R, et al. The BAG-1 isoform BAG-1M regulates keratin-associated Hsp70 chaperoning of aPKC in intestinal cells during activation of inflammatory signaling. J Cell Sci. 2014;127:3568-77 pubmed publisher
  • immunohistochemistry; mouse
Durak O, de Anda F, Singh K, Leussis M, Petryshen T, Sklar P, et al. Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of ?-catenin. Mol Psychiatry. 2015;20:388-97 pubmed publisher
  • immunocytochemistry; human; 1:500
Giusti S, Sbrana T, La Marca M, Di Patria V, Martinucci V, Tirella A, et al. A novel dual-flow bioreactor simulates increased fluorescein permeability in epithelial tissue barriers. Biotechnol J. 2014;9:1175-84 pubmed publisher
  • immunocytochemistry; mouse; 1:25
Doughton G, Wei J, Tapon N, Welham M, Chalmers A. Formation of a polarised primitive endoderm layer in embryoid bodies requires fgfr/erk signalling. PLoS ONE. 2014;9:e95434 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
Zhang J, Hatakeyama J, Eto K, Abe S. Reconstruction of a seminiferous tubule-like structure in a 3 dimensional culture system of re-aggregated mouse neonatal testicular cells within a collagen matrix. Gen Comp Endocrinol. 2014;205:121-32 pubmed publisher
  • immunohistochemistry - frozen section; rat
Satoh D, Hirose T, Harita Y, Daimon C, Harada T, Kurihara H, et al. aPKC? maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface. J Biochem. 2014;156:115-28 pubmed publisher
  • immunocytochemistry; domestic sheep; 1:100
Gross C, Aggarwal S, Kumar S, Tian J, Kása A, Bogatcheva N, et al. Sox18 preserves the pulmonary endothelial barrier under conditions of increased shear stress. J Cell Physiol. 2014;229:1802-16 pubmed publisher
  • immunocytochemistry; human; 1:100
Jeon J, Bersini S, Whisler J, Chen M, Dubini G, Charest J, et al. Generation of 3D functional microvascular networks with human mesenchymal stem cells in microfluidic systems. Integr Biol (Camb). 2014;6:555-63 pubmed publisher
  • immunocytochemistry; human; 1:100
  • immunohistochemistry; human; 1:100
Balk Møller E, Kim J, Hopkinson B, Timmermans Wielenga V, Petersen O, Villadsen R. A marker of endocrine receptor-positive cells, CEACAM6, is shared by two major classes of breast cancer: luminal and HER2-enriched. Am J Pathol. 2014;184:1198-208 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:100
Fitzpatrick P, Shattil S, Ablooglu A. C-terminal COOH of integrin ?1 is necessary for ?1 association with the kindlin-2 adapter protein. J Biol Chem. 2014;289:11183-93 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:500; fig 4
Alvers A, Ryan S, Scherz P, Huisken J, Bagnat M. Single continuous lumen formation in the zebrafish gut is mediated by smoothened-dependent tissue remodeling. Development. 2014;141:1110-9 pubmed publisher
  • immunocytochemistry; mouse; 1:300
Fong J, Nimlamool W, Falk M. EGF induces efficient Cx43 gap junction endocytosis in mouse embryonic stem cell colonies via phosphorylation of Ser262, Ser279/282, and Ser368. FEBS Lett. 2014;588:836-44 pubmed publisher
  • immunocytochemistry; human; 1:100
Lee J, Lee M. Decreased expression of zonula occludens-1 and occludin in the bladder urothelium of patients with interstitial cystitis/painful bladder syndrome. J Formos Med Assoc. 2014;113:17-22 pubmed publisher
  • immunocytochemistry; human; 1:100
Fiorentino M, Levine M, Sztein M, Fasano A. Effect of wild-type Shigella species and attenuated Shigella vaccine candidates on small intestinal barrier function, antigen trafficking, and cytokine release. PLoS ONE. 2014;9:e85211 pubmed publisher
  • immunocytochemistry; human; fig 6
Rigano L, Dowd G, Wang Y, Ireton K. Listeria monocytogenes antagonizes the human GTPase Cdc42 to promote bacterial spread. Cell Microbiol. 2014;16:1068-79 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:100
Neugebauer J, Yost H. FGF signaling is required for brain left-right asymmetry and brain midline formation. Dev Biol. 2014;386:123-34 pubmed publisher
  • immunohistochemistry - frozen section; zebrafish ; 1:25
Wang Y, Pan L, Moens C, Appel B. Notch3 establishes brain vascular integrity by regulating pericyte number. Development. 2014;141:307-17 pubmed publisher
  • immunohistochemistry - frozen section; human; fig 4
Robert J, Weber B, Frese L, Emmert M, Schmidt D, von Eckardstein A, et al. A three-dimensional engineered artery model for in vitro atherosclerosis research. PLoS ONE. 2013;8:e79821 pubmed publisher
  • immunocytochemistry; dogs; 1:25; fig 1
Andersen M, Krzystanek K, Petersen F, Bomholtz S, Olesen S, Abriel H, et al. A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein. J Biol Chem. 2013;288:36841-54 pubmed publisher
  • immunohistochemistry - frozen section; chicken; 1:100; fig 3
Lee R, Nagai H, Nakaya Y, Sheng G, Trainor P, Weston J, et al. Cell delamination in the mesencephalic neural fold and its implication for the origin of ectomesenchyme. Development. 2013;140:4890-902 pubmed publisher
  • western blot; human
Lázaro Diéguez F, Cohen D, Fernandez D, Hodgson L, Van IJzendoorn S, Müsch A. Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes. J Cell Biol. 2013;203:251-64 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Whiteman E, Fan S, Harder J, Walton K, Liu C, Soofi A, et al. Crumbs3 is essential for proper epithelial development and viability. Mol Cell Biol. 2014;34:43-56 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 3
Elamin E, Masclee A, Dekker J, Pieters H, Jonkers D. Short-chain fatty acids activate AMP-activated protein kinase and ameliorate ethanol-induced intestinal barrier dysfunction in Caco-2 cell monolayers. J Nutr. 2013;143:1872-81 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:200; fig 5
Schumacher J, Bloomekatz J, Garavito Aguilar Z, Yelon D. tal1 Regulates the formation of intercellular junctions and the maintenance of identity in the endocardium. Dev Biol. 2013;383:214-26 pubmed publisher
  • immunohistochemistry - frozen section; human; fig 8
Oie Y, Nozaki T, Takayanagi H, Hara S, Hayashi R, Takeda S, et al. Development of a cell sheet transportation technique for regenerative medicine. Tissue Eng Part C Methods. 2014;20:373-82 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 2
Isojima T, Harita Y, Furuyama M, Sugawara N, Ishizuka K, Horita S, et al. LMX1B mutation with residual transcriptional activity as a cause of isolated glomerulopathy. Nephrol Dial Transplant. 2014;29:81-8 pubmed publisher
  • immunocytochemistry; human; fig 1
Wittchen E, Nishimura E, McCloskey M, Wang H, Quilliam L, Chrzanowska Wodnicka M, et al. Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo. PLoS ONE. 2013;8:e73070 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4
Guichard A, Cruz Moreno B, Cruz Moreno B, Aguilar B, van Sorge N, Kuang J, et al. Cholera toxin disrupts barrier function by inhibiting exocyst-mediated trafficking of host proteins to intestinal cell junctions. Cell Host Microbe. 2013;14:294-305 pubmed publisher
  • immunocytochemistry; human; fig 6
Freedman B, Lam A, Sundsbak J, Iatrino R, Su X, Koon S, et al. Reduced ciliary polycystin-2 in induced pluripotent stem cells from polycystic kidney disease patients with PKD1 mutations. J Am Soc Nephrol. 2013;24:1571-86 pubmed publisher
  • immunocytochemistry; rat; 1:50; tbl 1
Wong E, Cheng C. NC1 domain of collagen ?3(IV) derived from the basement membrane regulates Sertoli cell blood-testis barrier dynamics. Spermatogenesis. 2013;3:e25465 pubmed
  • immunocytochemistry; mouse; 1:100; fig 3
Dunphy K, Seo J, Kim D, Roberts A, Tao L, DiRenzo J, et al. Oncogenic transformation of mammary epithelial cells by transforming growth factor beta independent of mammary stem cell regulation. Cancer Cell Int. 2013;13:74 pubmed publisher
  • immunocytochemistry; human
  • western blot; human; 1:1000
Siljamäki E, Raiko L, Toriseva M, Nissinen L, Näreoja T, Peltonen J, et al. p38? mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes. Arch Dermatol Res. 2014;306:131-41 pubmed publisher
  • western blot; human; fig 11
Kinoshita S, Kawasaki S, Kitazawa K, Shinomiya K. Establishment of a human conjunctival epithelial cell line lacking the functional TACSTD2 gene (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc. 2012;110:166-77 pubmed
  • immunohistochemistry; mouse; 1:100
Garriock R, Mikawa T, Yamaguchi T. Isolation and culture of mouse proepicardium using serum-free conditions. Methods. 2014;66:365-9 pubmed publisher
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
Elsum I, Martin C, Humbert P. Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation. J Cell Sci. 2013;126:3990-9 pubmed publisher
  • immunocytochemistry; human; 1:400; tbl 1
Murakami K, Kurihara C, Oka T, Shimoike T, Fujii Y, Takai Todaka R, et al. Norovirus binding to intestinal epithelial cells is independent of histo-blood group antigens. PLoS ONE. 2013;8:e66534 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 2
Lüthje P, Brauner H, Ramos N, Övregaard A, Gläser R, Hirschberg A, et al. Estrogen supports urothelial defense mechanisms. Sci Transl Med. 2013;5:190ra80 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 6
Wallingford M, Angelo J, Mager J. Morphogenetic analysis of peri-implantation development. Dev Dyn. 2013;242:1110-20 pubmed publisher
  • immunocytochemistry; human; fig 5
Jordan N, Prat A, Abell A, Zawistowski J, Sciaky N, Karginova O, et al. SWI/SNF chromatin-remodeling factor Smarcd3/Baf60c controls epithelial-mesenchymal transition by inducing Wnt5a signaling. Mol Cell Biol. 2013;33:3011-25 pubmed publisher
  • immunohistochemistry; Japanese rice fish; 1:400; fig 4
Herder C, Swiercz J, Müller C, Peravali R, Quiring R, Offermanns S, et al. ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation. Development. 2013;140:2787-97 pubmed publisher
  • immunocytochemistry; human; fig 2
Carrasco Pozo C, Morales P, Gotteland M. Polyphenols protect the epithelial barrier function of Caco-2 cells exposed to indomethacin through the modulation of occludin and zonula occludens-1 expression. J Agric Food Chem. 2013;61:5291-7 pubmed publisher
  • immunocytochemistry; dogs; 1:1000
Boehlke C, Kotsis F, Buchholz B, Powelske C, Eckardt K, Walz G, et al. Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells. PLoS ONE. 2013;8:e62165 pubmed publisher
  • immunocytochemistry; human; fig 1
Xu X, Jin D, Durgan J, Hall A. LKB1 controls human bronchial epithelial morphogenesis through p114RhoGEF-dependent RhoA activation. Mol Cell Biol. 2013;33:2671-82 pubmed publisher
  • western blot; domestic sheep; 1:5000; fig 2
Szczepkowska A, Lagaraine C, Robert V, Dufourny L, Thiery J, Skipor J. Effect of a two-week treatment with a low dose of 2,2'4,4',5,5'-hexachlorobiphenyl (PCB153) on tight junction protein expression in ovine choroid plexus during long and short photoperiods. Neurotoxicol Teratol. 2013;37:63-7 pubmed publisher
  • immunocytochemistry; rat; fig 2
Lin M, Shang D, Sun W, Li B, Xu X, Fang W, et al. Involvement of PI3K and ROCK signaling pathways in migration of bone marrow-derived mesenchymal stem cells through human brain microvascular endothelial cell monolayers. Brain Res. 2013;1513:1-8 pubmed publisher
  • immunocytochemistry; human; fig 6a
Fiorentino M, Lammers K, Levine M, Sztein M, Fasano A. In vitro Intestinal Mucosal Epithelial Responses to Wild-Type Salmonella Typhi and Attenuated Typhoid Vaccines. Front Immunol. 2013;4:17 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 2
  • western blot; human; 1:200; fig 2
Kirschner N, Rosenthal R, Furuse M, Moll I, Fromm M, Brandner J. Contribution of tight junction proteins to ion, macromolecule, and water barrier in keratinocytes. J Invest Dermatol. 2013;133:1161-9 pubmed publisher
  • immunocytochemistry; human; 1:80; tbl 1
Rachow S, Zorn Kruppa M, Ohnemus U, Kirschner N, Vidal Y Sy S, von den Driesch P, et al. Occludin is involved in adhesion, apoptosis, differentiation and Ca2+-homeostasis of human keratinocytes: implications for tumorigenesis. PLoS ONE. 2013;8:e55116 pubmed publisher
  • immunocytochemistry; human; 1:250; fig 2
Abu Khamidakh A, Juuti Uusitalo K, Larsson K, Skottman H, Hyttinen J. Intercellular Ca(2+) wave propagation in human retinal pigment epithelium cells induced by mechanical stimulation. Exp Eye Res. 2013;108:129-39 pubmed publisher
  • immunocytochemistry; Burton's mouthbrooder; 1:100
Mack A, Tiedemann K. Cultures of astroglial cells derived from brain of adult cichlid fish. J Neurosci Methods. 2013;212:269-75 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 4
Bouyer P, Tang X, Weber C, Shen L, Turner J, Matthews J. Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. Am J Physiol Gastrointest Liver Physiol. 2013;304:G142-56 pubmed publisher
  • immunocytochemistry; mouse; 1:750; fig 2
Antonica F, Kasprzyk D, Opitz R, Iacovino M, Liao X, Dumitrescu A, et al. Generation of functional thyroid from embryonic stem cells. Nature. 2012;491:66-71 pubmed publisher
  • immunocytochemistry; human; fig 4
  • western blot; human; fig 3
Langer M, Duggan E, Booth J, Patel V, Zander R, Silasi Mansat R, et al. Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function. Infect Immun. 2012;80:4374-87 pubmed publisher
  • immunocytochemistry; human; 1:250; fig 7
Cheung T, Ganatra M, Peters E, Truskey G. Effect of cellular senescence on the albumin permeability of blood-derived endothelial cells. Am J Physiol Heart Circ Physiol. 2012;303:H1374-83 pubmed publisher
  • immunocytochemistry; mouse
Termén S, Tan E, Heldin C, Moustakas A. p53 regulates epithelial-mesenchymal transition induced by transforming growth factor ?. J Cell Physiol. 2013;228:801-13 pubmed publisher
  • immunohistochemistry; mouse; fig 3
Vassilev V, Mandai M, Yonemura S, Takeichi M. Loss of N-cadherin from the endothelium causes stromal edema and epithelial dysgenesis in the mouse cornea. Invest Ophthalmol Vis Sci. 2012;53:7183-93 pubmed publisher
  • immunocytochemistry; human
Scudieri P, Caci E, Bruno S, Ferrera L, Schiavon M, Sondo E, et al. Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia. J Physiol. 2012;590:6141-55 pubmed publisher
  • immunocytochemistry; mouse; fig 4
Iden S, van Riel W, Schäfer R, Song J, Hirose T, Ohno S, et al. Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis. Cancer Cell. 2012;22:389-403 pubmed publisher
  • western blot; human; 1:500; fig 1
Castellani S, Guerra L, Favia M, Di Gioia S, Casavola V, Conese M. NHERF1 and CFTR restore tight junction organisation and function in cystic fibrosis airway epithelial cells: role of ezrin and the RhoA/ROCK pathway. Lab Invest. 2012;92:1527-40 pubmed publisher
  • immunohistochemistry; human; fig 3
Cunliffe H, Jiang Y, Fornace K, Yang F, Meltzer P. PAR6B is required for tight junction formation and activated PKC? localization in breast cancer. Am J Cancer Res. 2012;2:478-91 pubmed
  • immunocytochemistry; human; fig 3
Cantara S, Soscia D, Sequeira S, Jean Gilles R, Castracane J, Larsen M. Selective functionalization of nanofiber scaffolds to regulate salivary gland epithelial cell proliferation and polarity. Biomaterials. 2012;33:8372-82 pubmed publisher
  • immunocytochemistry; human; fig 3
Kalive M, Zhang W, Chen Y, Capco D. Human intestinal epithelial cells exhibit a cellular response indicating a potential toxicity upon exposure to hematite nanoparticles. Cell Biol Toxicol. 2012;28:343-68 pubmed publisher
  • immunohistochemistry - frozen section; chicken; 1:50; fig 2
Sanyas I, Bozon M, Moret F, Castellani V. Motoneuronal Sema3C is essential for setting stereotyped motor tract positioning in limb-derived chemotropic semaphorins. Development. 2012;139:3633-43 pubmed publisher
  • immunocytochemistry; human; 1:250; fig 4
Subrizi A, Hiidenmaa H, Ilmarinen T, Nymark S, Dubruel P, Uusitalo H, et al. Generation of hESC-derived retinal pigment epithelium on biopolymer coated polyimide membranes. Biomaterials. 2012;33:8047-54 pubmed publisher
  • immunohistochemistry; human; 1:500; fig 5
Magudia K, Lahoz A, Hall A. K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc. J Cell Biol. 2012;198:185-94 pubmed publisher
  • western blot; human; fig 2
Moran G, O NEILL C, McLaughlin J. GLP-2 enhances barrier formation and attenuates TNF?-induced changes in a Caco-2 cell model of the intestinal barrier. Regul Pept. 2012;178:95-101 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:750
Mühlfeld S, Domanova O, Berlage T, Stross C, Helmer A, Keitel V, et al. Short-term feedback regulation of bile salt uptake by bile salts in rodent liver. Hepatology. 2012;56:2387-97 pubmed publisher
  • immunocytochemistry; dogs; 5 ug/ml; fig 1
Kuo K, Zhu H, McNamara P, Leggas M. Localization and functional characterization of the rat Oatp4c1 transporter in an in vitro cell system and rat tissues. PLoS ONE. 2012;7:e39641 pubmed publisher
  • immunohistochemistry; human; fig 1
Kajiho Y, Harita Y, Kurihara H, Horita S, Matsunaga A, Tsurumi H, et al. SIRP? interacts with nephrin at the podocyte slit diaphragm. FEBS J. 2012;279:3010-21 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 6
  • western blot; mouse; 1:1000; fig 2
Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, et al. PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013;23:1824-35 pubmed publisher
  • immunocytochemistry; dogs; 1:500; fig s1
Hartsock A, Nelson W. Competitive regulation of E-cadherin juxtamembrane domain degradation by p120-catenin binding and Hakai-mediated ubiquitination. PLoS ONE. 2012;7:e37476 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 8
Ohmura T, Shioi G, Hirano M, Aizawa S. Neural tube defects by NUAK1 and NUAK2 double mutation. Dev Dyn. 2012;241:1350-64 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50
Keay S, Leitzell S, Ochrzcin A, Clements G, Zhan M, Johnson D. A mouse model for interstitial cystitis/painful bladder syndrome based on APF inhibition of bladder epithelial repair: a pilot study. BMC Urol. 2012;12:17 pubmed
  • immunocytochemistry; human; fig 4
  • western blot; human; fig 2
Raiko L, Siljamäki E, Mahoney M, Putaala H, Suominen E, Peltonen J, et al. Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding Ca(2+) /Mn(2+) ATPase SPCA1 in cultured keratinocytes. Exp Dermatol. 2012;21:586-91 pubmed publisher
  • immunohistochemistry; mouse; 1:400; fig 4
Saund R, Kanai Azuma M, Kanai Y, Kim I, Lucero M, Saijoh Y. Gut endoderm is involved in the transfer of left-right asymmetry from the node to the lateral plate mesoderm in the mouse embryo. Development. 2012;139:2426-35 pubmed publisher
  • immunocytochemistry; human; fig 3
Adijanto J, Castorino J, Wang Z, Maminishkis A, Grunwald G, Philp N. Microphthalmia-associated transcription factor (MITF) promotes differentiation of human retinal pigment epithelium (RPE) by regulating microRNAs-204/211 expression. J Biol Chem. 2012;287:20491-503 pubmed publisher
  • immunohistochemistry; human; 15 ug/ml; fig 5
Rowland T, Blaschke A, Buchholz D, Hikita S, Johnson L, Clegg D. Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. J Tissue Eng Regen Med. 2013;7:642-53 pubmed publisher
  • immunohistochemistry - frozen section; domestic rabbit; 1:200; fig 2
Jiang X, Guo M, Su J, Lu B, Ma D, Zhang R, et al. Simvastatin blocks blood-brain barrier disruptions induced by elevated cholesterol both in vivo and in vitro. Int J Alzheimers Dis. 2012;2012:109324 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 4
Cammas L, Wolfe J, Choi S, Dedhar S, Beggs H. Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. Invest Ophthalmol Vis Sci. 2012;53:3067-81 pubmed publisher
  • immunocytochemistry; human; 1:400; fig 7
Ting L, Jahn J, Jung J, Shuman B, Feghhi S, Han S, et al. Flow mechanotransduction regulates traction forces, intercellular forces, and adherens junctions. Am J Physiol Heart Circ Physiol. 2012;302:H2220-9 pubmed publisher
  • immunohistochemistry - paraffin section; domestic rabbit; 1:200; fig 4
Ritchie J, Rui H, Zhou X, Iida T, Kodoma T, Ito S, et al. Inflammation and disintegration of intestinal villi in an experimental model for Vibrio parahaemolyticus-induced diarrhea. PLoS Pathog. 2012;8:e1002593 pubmed publisher
  • immunocytochemistry; dogs; fig 4
Liu K, Jacobs D, Dunn B, Fanning A, Cheney R. Myosin-X functions in polarized epithelial cells. Mol Biol Cell. 2012;23:1675-87 pubmed publisher
  • immunocytochemistry; dogs; fig 1
Dukes J, Whitley P, Chalmers A. The PIKfyve inhibitor YM201636 blocks the continuous recycling of the tight junction proteins claudin-1 and claudin-2 in MDCK cells. PLoS ONE. 2012;7:e28659 pubmed publisher
  • immunohistochemistry; goldfish; 1:100
Parrilla M, Lillo C, Herrero Turrion M, Arevalo R, Aijón J, Lara J, et al. Characterization of Pax2 expression in the goldfish optic nerve head during retina regeneration. PLoS ONE. 2012;7:e32348 pubmed publisher
  • immunocytochemistry; dogs; fig 2
Paschoud S, Guillemot L, Citi S. Distinct domains of paracingulin are involved in its targeting to the actin cytoskeleton and regulation of apical junction assembly. J Biol Chem. 2012;287:13159-69 pubmed publisher
  • immunocytochemistry; human; fig 2
Shi Y, Kirwan P, Smith J, Robinson H, Livesey F. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat Neurosci. 2012;15:477-86, S1 pubmed publisher
  • immunocytochemistry; zebrafish ; fig 4
Kim J, Rubin N, Huang Y, Tuan T, Lien C. In vitro culture of epicardial cells from adult zebrafish heart on a fibrin matrix. Nat Protoc. 2012;7:247-55 pubmed publisher
  • immunohistochemistry; human; 1:200
He Z, Campolmi N, Ha Thi B, Dumollard J, Peoc h M, Garraud O, et al. Optimization of immunolocalization of cell cycle proteins in human corneal endothelial cells. Mol Vis. 2011;17:3494-511 pubmed
  • western blot; mouse; fig 6
Ortega Cava C, Raja S, Laiq Z, Bailey T, Luan H, Mohapatra B, et al. Continuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer. J Carcinog. 2011;10:29 pubmed publisher
  • immunocytochemistry; mouse
Schneckenleithner C, Bago Horvath Z, Dolznig H, Neugebauer N, Kollmann K, Kolbe T, et al. Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias. Oncotarget. 2011;2:1043-54 pubmed
  • western blot; mouse; fig 1
Sarró E, Jacobs Cachá C, Itarte E, Meseguer A. A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells. Toxicol Appl Pharmacol. 2012;258:275-87 pubmed publisher
  • immunohistochemistry; African green monkey; 1:200; fig 3
Kelava I, Reillo I, Murayama A, Kalinka A, Stenzel D, Tomancak P, et al. Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus. Cereb Cortex. 2012;22:469-81 pubmed publisher
  • immunocytochemistry; human; fig 4
  • western blot; human; fig 1
Brysse A, Mestdagt M, Polette M, Luczka E, Hunziker W, Noel A, et al. Regulation of CXCL8/IL-8 expression by zonula occludens-1 in human breast cancer cells. Mol Cancer Res. 2012;10:121-32 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:100; fig 3
Gendron R, Armstrong E, Paradis H, Haines L, Desjardins M, Short C, et al. Osmotic pressure-adaptive responses in the eye tissues of rainbow smelt (Osmerus mordax). Mol Vis. 2011;17:2596-604 pubmed
  • western blot; dogs; fig 7
Knauf F, Ko N, Jiang Z, Robertson W, Van Itallie C, Anderson J, et al. Net intestinal transport of oxalate reflects passive absorption and SLC26A6-mediated secretion. J Am Soc Nephrol. 2011;22:2247-55 pubmed publisher
  • immunohistochemistry - frozen section; zebrafish ; 1:20; fig 3
Münzel E, Schaefer K, Obirei B, Kremmer E, Burton E, Kuscha V, et al. Claudin k is specifically expressed in cells that form myelin during development of the nervous system and regeneration of the optic nerve in adult zebrafish. Glia. 2012;60:253-70 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:400; fig 4
Cheung I, Bagnat M, Ma T, Datta A, Evason K, Moore J, et al. Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. Dev Biol. 2012;361:68-78 pubmed publisher
  • western blot; human; fig 4
Koning H, Sayers I, Stewart C, de Jong D, ten Hacken N, Postma D, et al. Characterization of protocadherin-1 expression in primary bronchial epithelial cells: association with epithelial cell differentiation. FASEB J. 2012;26:439-48 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4
Chai Z, Goodenough D, Paul D. Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels. Mol Biol Cell. 2011;22:4503-12 pubmed publisher
  • immunohistochemistry; human; 1.25 ug/ml; fig 3
Subramaniam R, Hinley J, Stahlschmidt J, Southgate J. Tissue engineering potential of urothelial cells from diseased bladders. J Urol. 2011;186:2014-20 pubmed publisher
  • immunocytochemistry; mouse; fig 5
Carman A, Mills J, Krenz A, Kim D, Bynoe M. Adenosine receptor signaling modulates permeability of the blood-brain barrier. J Neurosci. 2011;31:13272-80 pubmed publisher
  • immunohistochemistry; mouse; fig 2
Calame M, Cachafeiro M, Philippe S, Schouwey K, Tekaya M, Wanner D, et al. Retinal degeneration progression changes lentiviral vector cell targeting in the retina. PLoS ONE. 2011;6:e23782 pubmed publisher
  • immunohistochemistry; mouse; fig 2
Grosse A, Pressprich M, Curley L, Hamilton K, Margolis B, Hildebrand J, et al. Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis. Development. 2011;138:4423-32 pubmed publisher
  • immunohistochemistry; zebrafish ; fig 4
Gao W, Xu L, Guan R, Liu X, Han Y, Wu Q, et al. Wdr18 is required for Kupffer's vesicle formation and regulation of body asymmetry in zebrafish. PLoS ONE. 2011;6:e23386 pubmed publisher
  • immunohistochemistry; dogs; 2.5 ug/ml; loading ...; fig 4f
Ohta H, Yamaguchi T, Rajapakshage B, Murakami M, Sasaki N, Nakamura K, et al. Expression and subcellular localization of apical junction proteins in canine duodenal and colonic mucosa. Am J Vet Res. 2011;72:1046-51 pubmed publisher
  • immunocytochemistry; human; 1.25 ug/ml; fig 7
Smith N, Varley C, Eardley I, Feather S, Trejdosiewicz L, Southgate J. Toll-like receptor responses of normal human urothelial cells to bacterial flagellin and lipopolysaccharide. J Urol. 2011;186:1084-92 pubmed publisher
  • immunocytochemistry; human; 1:150; fig 1
Mandel I, Paperna T, Glass Marmor L, Volkowich A, Badarny S, Schwartz I, et al. Tight junction proteins expression and modulation in immune cells and multiple sclerosis. J Cell Mol Med. 2012;16:765-75 pubmed publisher
  • immunocytochemistry; dogs; 1:25; fig 1
Dukes J, Fish L, Richardson J, Blaikley E, Burns S, Caunt C, et al. Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells. Mol Biol Cell. 2011;22:3192-205 pubmed publisher
  • western blot; human; fig 4
Belgiovine C, Chiodi I, Mondello C. Relocalization of cell adhesion molecules during neoplastic transformation of human fibroblasts. Int J Oncol. 2011;39:1199-204 pubmed publisher
  • immunocytochemistry; dogs
Kumar H, Rangrez A, Dayananda K, Atre A, Patole M, Shouche Y. Lactobacillus plantarum (VR1) isolated from an ayurvedic medicine (Kutajarista) ameliorates in vitro cellular damage caused by Aeromonas veronii. BMC Microbiol. 2011;11:152 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50
Sun Z, Shushanov S, LeRoith D, Wood T. Decreased IGF type 1 receptor signaling in mammary epithelium during pregnancy leads to reduced proliferation, alveolar differentiation, and expression of insulin receptor substrate (IRS)-1 and IRS-2. Endocrinology. 2011;152:3233-45 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4
Watanabe R, Hayashi R, Kimura Y, Tanaka Y, Kageyama T, Hara S, et al. A novel gelatin hydrogel carrier sheet for corneal endothelial transplantation. Tissue Eng Part A. 2011;17:2213-9 pubmed publisher
  • western blot; domestic sheep; 1:5000; fig 3
Lagaraine C, Skipor J, Szczepkowska A, Dufourny L, Thiery J. Tight junction proteins vary in the choroid plexus of ewes according to photoperiod. Brain Res. 2011;1393:44-51 pubmed publisher
  • immunocytochemistry; human; fig 3
Llaurado M, Abal M, Castellvi J, Cabrera S, Gil Moreno A, Pérez Benavente A, et al. ETV5 transcription factor is overexpressed in ovarian cancer and regulates cell adhesion in ovarian cancer cells. Int J Cancer. 2012;130:1532-43 pubmed publisher
  • western blot; pigs ; fig 1
Butt O, Buehler P, D Agnillo F. Blood-brain barrier disruption and oxidative stress in guinea pig after systemic exposure to modified cell-free hemoglobin. Am J Pathol. 2011;178:1316-28 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 3
Wu W, Huang Q, He F, Xiao M, Pang S, Guo X, et al. Roles of mitogen-activated protein kinases in the modulation of endothelial cell function following thermal injury. Shock. 2011;35:618-25 pubmed publisher
  • immunocytochemistry; mouse; 1:50; fig 2
Tanigawa S, Wang H, Yang Y, Sharma N, Tarasova N, Ajima R, et al. Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism. Dev Biol. 2011;352:58-69 pubmed publisher
  • immunocytochemistry; pigs ; 1:200; fig 2
Iqbal M, Gibb W, Matthews S. Corticosteroid regulation of P-glycoprotein in the developing blood-brain barrier. Endocrinology. 2011;152:1067-79 pubmed publisher
  • immunocytochemistry; human; fig 2
Andersen M, Olesen S, Rasmussen H. Kv7.1 surface expression is regulated by epithelial cell polarization. Am J Physiol Cell Physiol. 2011;300:C814-24 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 5 ug/ml; fig 3
Larsen H, Aure M, Peters S, Larsen M, Messelt E, Kanli Galtung H. Localization of AQP5 during development of the mouse submandibular salivary gland. J Mol Histol. 2011;42:71-81 pubmed publisher
  • western blot; mouse; 1:200
Hilgen G, von Maltzahn J, Willecke K, Weiler R, Dedek K. Subcellular distribution of connexin45 in OFF bipolar cells of the mouse retina. J Comp Neurol. 2011;519:433-50 pubmed publisher
  • immunohistochemistry; mouse; fig 2
  • western blot; mouse; fig 2
Kirschner N, Haftek M, Niessen C, Behne M, Furuse M, Moll I, et al. CD44 regulates tight-junction assembly and barrier function. J Invest Dermatol. 2011;131:932-43 pubmed publisher
  • immunohistochemistry; human; fig 5
Maria O, Zeitouni A, Gologan O, Tran S. Matrigel improves functional properties of primary human salivary gland cells. Tissue Eng Part A. 2011;17:1229-38 pubmed publisher
  • immunocytochemistry; dogs; 1:40; fig 4
Paschoud S, Yu D, Pulimeno P, Jond L, Turner J, Citi S. Cingulin and paracingulin show similar dynamic behaviour, but are recruited independently to junctions. Mol Membr Biol. 2011;28:123-35 pubmed publisher
  • western blot; human
Liu M, Sakamaki T, Casimiro M, Willmarth N, Quong A, Ju X, et al. The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion. Cancer Res. 2010;70:10464-73 pubmed publisher
  • immunocytochemistry; human; fig 6
Kranjec C, Banks L. A systematic analysis of human papillomavirus (HPV) E6 PDZ substrates identifies MAGI-1 as a major target of HPV type 16 (HPV-16) and HPV-18 whose loss accompanies disruption of tight junctions. J Virol. 2011;85:1757-64 pubmed publisher
  • immunocytochemistry; human; tbl 1
Ingthorsson S, Halldorsson T, Sigurdsson V, Friðriksdottir A, Bodvarsdottir S, Steinarsdottir M, et al. Selection for EGFR gene amplification in a breast epithelial cell line with basal-like phenotype and hereditary background. In Vitro Cell Dev Biol Anim. 2011;47:139-48 pubmed publisher
  • immunocytochemistry; human; fig 1
Haarmann A, Deiss A, Prochaska J, Foerch C, Weksler B, Romero I, et al. Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown. PLoS ONE. 2010;5:e13568 pubmed publisher
  • western blot; human; fig 3
Wallace S, Magalhaes A, Hall A. The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells. Mol Cell Biol. 2011;31:81-91 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:500; fig 7
Aman A, Nguyen M, Piotrowski T. Wnt/β-catenin dependent cell proliferation underlies segmented lateral line morphogenesis. Dev Biol. 2011;349:470-82 pubmed publisher
  • immunohistochemistry - frozen section; zebrafish ; 1:100
Grupp L, Wolburg H, Mack A. Astroglial structures in the zebrafish brain. J Comp Neurol. 2010;518:4277-87 pubmed publisher
  • immunohistochemistry; zebrafish
Ablooglu A, Tkachenko E, Kang J, Shattil S. Integrin alphaV is necessary for gastrulation movements that regulate vertebrate body asymmetry. Development. 2010;137:3449-58 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:200; fig 4
Garavito Aguilar Z, Riley H, Yelon D. Hand2 ensures an appropriate environment for cardiac fusion by limiting Fibronectin function. Development. 2010;137:3215-20 pubmed publisher
  • western blot; dogs; 1:1000; fig 6
Boassa D, Solan J, Papas A, Thornton P, Lampe P, Sosinsky G. Trafficking and recycling of the connexin43 gap junction protein during mitosis. Traffic. 2010;11:1471-86 pubmed publisher
  • immunohistochemistry; mouse; 1:300; fig 1
Hirota Y, Meunier A, Huang S, Shimozawa T, Yamada O, Kida Y, et al. Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II. Development. 2010;137:3037-46 pubmed publisher
  • immunocytochemistry; human; fig 5
  • immunohistochemistry; human; fig 2
  • western blot; human; fig 2
Nakatsukasa M, Kawasaki S, Yamasaki K, Fukuoka H, Matsuda A, Tsujikawa M, et al. Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy. Am J Pathol. 2010;177:1344-55 pubmed publisher
  • western blot; bovine; fig 3
Ponsaerts R, De Vuyst E, Retamal M, D hondt C, Vermeire D, Wang N, et al. Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity. FASEB J. 2010;24:4378-95 pubmed publisher
  • immunocytochemistry; human; fig 2
Wallace S, Durgan J, Jin D, Hall A. Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B. Mol Biol Cell. 2010;21:2996-3006 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 6
Martello G, Rosato A, Ferrari F, Manfrin A, Cordenonsi M, Dupont S, et al. A MicroRNA targeting dicer for metastasis control. Cell. 2010;141:1195-207 pubmed publisher
  • immunocytochemistry; human; fig 4
Oie Y, Hayashi R, Takagi R, Yamato M, Takayanagi H, Tano Y, et al. A novel method of culturing human oral mucosal epithelial cell sheet using post-mitotic human dermal fibroblast feeder cells and modified keratinocyte culture medium for ocular surface reconstruction. Br J Ophthalmol. 2010;94:1244-50 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig s1
Fietz S, Kelava I, Vogt J, Wilsch Bräuninger M, Stenzel D, Fish J, et al. OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling. Nat Neurosci. 2010;13:690-9 pubmed publisher
  • immunocytochemistry; rhesus macaque; 1:15; fig 5
Mazumdar K, Alvarez X, Borda J, Dufour J, Martin E, Bethune M, et al. Visualization of transepithelial passage of the immunogenic 33-residue peptide from alpha-2 gliadin in gluten-sensitive macaques. PLoS ONE. 2010;5:e10228 pubmed publisher
  • immunohistochemistry - frozen section; rat; fig 1
  • western blot; rat; fig 3
Morishige N, Ko J, Morita Y, Nishida T. Expression of semaphorin 3A in the rat corneal epithelium during wound healing. Biochem Biophys Res Commun. 2010;395:451-7 pubmed publisher
  • immunocytochemistry; dogs; fig 2
  • immunocytochemistry; human; fig 2
Jeanes A, Smutny M, Leerberg J, Yap A. Phosphatidylinositol 3'-kinase signalling supports cell height in established epithelial monolayers. J Mol Histol. 2009;40:395-405 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 9
Lesimple P, Liao J, Robert R, Gruenert D, Hanrahan J. Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers. J Physiol. 2010;588:1195-209 pubmed publisher
  • immunohistochemistry; human; 1:50; fig 3a
  • immunohistochemistry; cat; 1:50; fig 3c
Karim M, Biswas S, Bhattacherjee P, Paterson C. Comparison of tight junction protein expression in the ciliary epithelia of mouse, rabbit, cat and human eyes. Biotech Histochem. 2011;86:161-7 pubmed publisher
  • flow cytometry; human; tbl 2
Semenov O, Koestenbauer S, Riegel M, Zech N, Zimmermann R, Zisch A, et al. Multipotent mesenchymal stem cells from human placenta: critical parameters for isolation and maintenance of stemness after isolation. Am J Obstet Gynecol. 2010;202:193.e1-193.e13 pubmed publisher
  • immunocytochemistry; human; 1:25; fig 3
  • western blot; human; 1:1000; fig 3
Joannes A, Bonnomet A, Bindels S, Polette M, Gilles C, Burlet H, et al. Fhit regulates invasion of lung tumor cells. Oncogene. 2010;29:1203-13 pubmed publisher
  • western blot; domestic sheep; 1:5000; fig 2d
Sadowska G, Malaeb S, Stonestreet B. Maternal glucocorticoid exposure alters tight junction protein expression in the brain of fetal sheep. Am J Physiol Heart Circ Physiol. 2010;298:H179-88 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5
Sugiyama Y, Akimoto K, Robinson M, Ohno S, Quinlan R. A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009;336:246-56 pubmed publisher
  • immunocytochemistry; human
Rajabian T, Gavicherla B, Heisig M, Müller Altrock S, Goebel W, Gray Owen S, et al. The bacterial virulence factor InlC perturbs apical cell junctions and promotes cell-to-cell spread of Listeria. Nat Cell Biol. 2009;11:1212-8 pubmed publisher
  • immunocytochemistry; human; fig 1
Ignáth I, Hegyi P, Venglovecz V, Székely C, Carr G, Hasegawa M, et al. CFTR expression but not Cl- transport is involved in the stimulatory effect of bile acids on apical Cl-/HCO3- exchange activity in human pancreatic duct cells. Pancreas. 2009;38:921-9 pubmed publisher
  • immunohistochemistry - frozen section; human; fig 4
Hayashi R, Yamato M, Takayanagi H, Oie Y, Kubota A, Hori Y, et al. Validation system of tissue-engineered epithelial cell sheets for corneal regenerative medicine. Tissue Eng Part C Methods. 2010;16:553-60 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:50; fig 1
Shimazaki J, Higa K, Kato N, Satake Y. Barrier function of cultivated limbal and oral mucosal epithelial cell sheets. Invest Ophthalmol Vis Sci. 2009;50:5672-80 pubmed publisher
  • immunoprecipitation; human; fig 5
  • western blot; human; fig 5
Matsumoto M, Oyamada K, Takahashi H, Sato T, Hatakeyama S, Nakayama K. Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways. Proteomics. 2009;9:3549-63 pubmed publisher
  • immunocytochemistry; human; fig 3
Natoli M, Felsani A, Ferruzza S, Sambuy Y, Canali R, Scarino M. Mechanisms of defence from Fe(II) toxicity in human intestinal Caco-2 cells. Toxicol In Vitro. 2009;23:1510-5 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:5; fig 4
  • western blot; rat; 1:500; fig 7
Sobarzo C, Lustig L, Ponzio R, Suescun M, Denduchis B. Effects of di(2-ethylhexyl) phthalate on gap and tight junction protein expression in the testis of prepubertal rats. Microsc Res Tech. 2009;72:868-77 pubmed publisher
  • immunocytochemistry; zebrafish ; fig 5k
Montero Balaguer M, Swirsding K, Orsenigo F, Cotelli F, Mione M, Dejana E. Stable vascular connections and remodeling require full expression of VE-cadherin in zebrafish embryos. PLoS ONE. 2009;4:e5772 pubmed publisher
  • immunocytochemistry; zebrafish ; 1:200; fig 5
Roberts R, Appel B. Apical polarity protein PrkCi is necessary for maintenance of spinal cord precursors in zebrafish. Dev Dyn. 2009;238:1638-48 pubmed publisher
  • immunohistochemistry; Trachemys dorbigni; 1:500
Rehermann M, Marichal N, RUSSO R, TRUJILLO CENOZ O. Neural reconnection in the transected spinal cord of the freshwater turtle Trachemys dorbignyi. J Comp Neurol. 2009;515:197-214 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 7
Cukierman L, Meertens L, Bertaux C, Kajumo F, Dragic T. Residues in a highly conserved claudin-1 motif are required for hepatitis C virus entry and mediate the formation of cell-cell contacts. J Virol. 2009;83:5477-84 pubmed publisher
  • immunocytochemistry; human; 1 ug/ml; fig 1
Elwi A, Damaraju V, Kuzma M, Mowles D, Baldwin S, Young J, et al. Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3. Am J Physiol Renal Physiol. 2009;296:F1439-51 pubmed publisher
  • immunocytochemistry; dogs; fig 1
Li H, Collier J, Shawki A, Rudra J, Li E, Mackenzie B, et al. Sequence- or position-specific mutations in the carboxyl-terminal FL motif of the kidney sodium bicarbonate cotransporter (NBC1) disrupt its basolateral targeting and alpha-helical structure. J Membr Biol. 2009;228:111-24 pubmed publisher
  • immunohistochemistry - frozen section; rat; fig 4
  • immunohistochemistry - frozen section; mouse; fig 3
Huber T, Hartleben B, Winkelmann K, Schneider L, Becker J, Leitges M, et al. Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome. J Am Soc Nephrol. 2009;20:798-806 pubmed publisher
  • immunocytochemistry; zebrafish ; 1:150; fig s7
Neugebauer J, Amack J, Peterson A, Bisgrove B, Yost H. FGF signalling during embryo development regulates cilia length in diverse epithelia. Nature. 2009;458:651-4 pubmed publisher
  • immunohistochemistry; mouse
Burtscher I, Lickert H. Foxa2 regulates polarity and epithelialization in the endoderm germ layer of the mouse embryo. Development. 2009;136:1029-38 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100; fig 1
Alanne M, Pummi K, Heape A, Grenman R, Peltonen J, Peltonen S. Tight junction proteins in human Schwann cell autotypic junctions. J Histochem Cytochem. 2009;57:523-9 pubmed publisher
  • immunohistochemistry - frozen section; domestic rabbit; 1:200; tbl 1
Takaoka M, Nakamura T, Sugai H, Bentley A, Nakajima N, Yokoi N, et al. Novel sutureless keratoplasty with a chemically defined bioadhesive. Invest Ophthalmol Vis Sci. 2009;50:2679-85 pubmed publisher
  • immunocytochemistry; human; 1:50; loading ...; fig 4
  • western blot; human; loading ...; fig 3a
McLaughlin J, Lambert D, Padfield P, Burt J, O Neill C. The mycotoxin patulin, modulates tight junctions in caco-2 cells. Toxicol In Vitro. 2009;23:83-9 pubmed publisher
  • immunocytochemistry; mouse; 1 ug/ml
Catanuto P, Espinosa Heidmann D, Pereira Simon S, Sanchez P, Salas P, Hernandez E, et al. Mouse retinal pigmented epithelial cell lines retain their phenotypic characteristics after transfection with human papilloma virus: a new tool to further the study of RPE biology. Exp Eye Res. 2009;88:99-105 pubmed publisher
  • immunocytochemistry; human; fig 2
Dunworth W, Fritz Six K, Caron K. Adrenomedullin stabilizes the lymphatic endothelial barrier in vitro and in vivo. Peptides. 2008;29:2243-9 pubmed publisher
  • immunocytochemistry; human; fig 6c
Yang W, Hood B, Chadwick S, Liu S, Watkins S, Luo G, et al. Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and production. Hepatology. 2008;48:1396-403 pubmed publisher
  • immunocytochemistry; human; fig 3a
Neuhaus W, Wirth M, Plattner V, Germann B, Gabor F, Noe C. Expression of Claudin-1, Claudin-3 and Claudin-5 in human blood-brain barrier mimicking cell line ECV304 is inducible by glioma-conditioned media. Neurosci Lett. 2008;446:59-64 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 5
  • western blot; mouse; 1:1000; fig 5
Chen X, Lan X, Roche I, Liu R, Geiger J. Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum. J Neurochem. 2008;107:1147-57 pubmed publisher
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 1
Aono S, Hirai Y. Phosphorylation of claudin-4 is required for tight junction formation in a human keratinocyte cell line. Exp Cell Res. 2008;314:3326-39 pubmed publisher
  • immunocytochemistry; dogs; fig 1b
Nokes R, Fields I, Collins R, FOLSCH H. Rab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells. J Cell Biol. 2008;182:845-53 pubmed publisher
  • immunocytochemistry; human; 1.25 ug/ml; tbl 2
Rubenwolf P, Georgopoulos N, Clements L, Feather S, Holland P, Thomas D, et al. Expression and localisation of aquaporin water channels in human urothelium in situ and in vitro. Eur Urol. 2009;56:1013-23 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; tbl 2
Cain S, Martinez G, Kokkinos M, Turner K, Richardson R, Abud H, et al. Differential requirement for beta-catenin in epithelial and fiber cells during lens development. Dev Biol. 2008;321:420-33 pubmed publisher
  • immunohistochemistry; rat; fig 2
  • western blot; rat; fig 5
McCaffrey G, Seelbach M, Staatz W, Nametz N, Quigley C, Campos C, et al. Occludin oligomeric assembly at tight junctions of the blood-brain barrier is disrupted by peripheral inflammatory hyperalgesia. J Neurochem. 2008;106:2395-409 pubmed publisher
  • immunocytochemistry; mouse; fig 1
Kishikawa M, Suzuki A, Ohno S. aPKC enables development of zonula adherens by antagonizing centripetal contraction of the circumferential actomyosin cables. J Cell Sci. 2008;121:2481-92 pubmed publisher
  • immunohistochemistry; rat; fig 1g
Roberts L, Black D, Raman C, Woodford K, Zhou M, Haggerty J, et al. Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation. Neuroscience. 2008;155:423-38 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100
Norsted E, Gömüç B, Meister B. Protein components of the blood-brain barrier (BBB) in the mediobasal hypothalamus. J Chem Neuroanat. 2008;36:107-21 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 2a
Bouschbacher M, Bomsel M, Verronèse E, Gofflo S, Ganor Y, Dezutter Dambuyant C, et al. Early events in HIV transmission through a human reconstructed vaginal mucosa. AIDS. 2008;22:1257-66 pubmed publisher
  • western blot; dogs; fig 1b
  • immunohistochemistry; bovine; fig 4b
  • western blot; bovine; fig 1b
Sugiyama Y, Prescott A, Tholozan F, Ohno S, Quinlan R. Expression and localisation of apical junctional complex proteins in lens epithelial cells. Exp Eye Res. 2008;87:64-70 pubmed publisher
  • flow cytometry; human; fig 4
Birnie R, Bryce S, Roome C, Dussupt V, Droop A, Lang S, et al. Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions. Genome Biol. 2008;9:R83 pubmed publisher
  • immunohistochemistry; pigs ; 5 mg/ml; fig 4
Turner A, Subramaniam R, Thomas D, Southgate J. Generation of a functional, differentiated porcine urothelial tissue in vitro. Eur Urol. 2008;54:1423-32 pubmed publisher
  • immunohistochemistry - frozen section; domestic rabbit; fig 6
  • western blot; domestic rabbit; fig 4
Chen X, Gawryluk J, Wagener J, Ghribi O, Geiger J. Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease. J Neuroinflammation. 2008;5:12 pubmed publisher
  • immunohistochemistry; rat; fig 5
Morishige N, Ko J, Liu Y, Chikama T, Nishida T. Localization of semaphorin 3A in the rat cornea. Exp Eye Res. 2008;86:669-74 pubmed publisher
  • immunocytochemistry; human
Yang W, Qiu C, Biswas N, Jin J, Watkins S, Montelaro R, et al. Correlation of the tight junction-like distribution of Claudin-1 to the cellular tropism of hepatitis C virus. J Biol Chem. 2008;283:8643-53 pubmed publisher
  • immunocytochemistry; mouse; fig 6
Li J, Levin M, Xiong Y, Petrenko N, Patel V, Radice G. N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility. J Mol Cell Cardiol. 2008;44:597-606 pubmed publisher
  • immunocytochemistry; human; fig 1
Imayasu M, Shiraishi A, Ohashi Y, Shimada S, Cavanagh H. Effects of multipurpose solutions on corneal epithelial tight junctions. Eye Contact Lens. 2008;34:50-5 pubmed publisher
  • immunocytochemistry; dogs; fig 5
  • western blot; dogs; fig 3
Paschoud S, Citi S. Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression. Mol Membr Biol. 2008;25:1-13 pubmed
  • immunohistochemistry - frozen section; mouse; fig 4
Konno D, Shioi G, Shitamukai A, Mori A, Kiyonari H, Miyata T, et al. Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. Nat Cell Biol. 2008;10:93-101 pubmed
  • immunohistochemistry; mouse; 1:100
Nishioka N, Yamamoto S, Kiyonari H, Sato H, Sawada A, Ota M, et al. Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos. Mech Dev. 2008;125:270-83 pubmed
  • immunocytochemistry; mouse
Kawaguchi M, Bader D, Wilm B. Serosal mesothelium retains vasculogenic potential. Dev Dyn. 2007;236:2973-9 pubmed
  • immunocytochemistry; rat; 1:100; fig 1
  • western blot; rat; 1:1000; fig 1
McCaffrey G, Staatz W, Quigley C, Nametz N, Seelbach M, Campos C, et al. Tight junctions contain oligomeric protein assembly critical for maintaining blood-brain barrier integrity in vivo. J Neurochem. 2007;103:2540-55 pubmed publisher
  • immunocytochemistry; human
Weber K, Fischer R, Fowler V. Tmod3 regulates polarized epithelial cell morphology. J Cell Sci. 2007;120:3625-32 pubmed
  • immunohistochemistry; human; 1:400; fig 1
Kostin S. Zonula occludens-1 and connexin 43 expression in the failing human heart. J Cell Mol Med. 2007;11:892-5 pubmed
  • immunocytochemistry; human; fig 2
Mandell K, Berglin L, Severson E, Edelhauser H, Parkos C. Expression of JAM-A in the human corneal endothelium and retinal pigment epithelium: localization and evidence for role in barrier function. Invest Ophthalmol Vis Sci. 2007;48:3928-36 pubmed
  • immunohistochemistry; mouse; 4 ug/ml
Ciolofan C, Lynn B, Wellershaus K, Willecke K, Nagy J. Spatial relationships of connexin36, connexin57 and zonula occludens-1 in the outer plexiform layer of mouse retina. Neuroscience. 2007;148:473-88 pubmed
  • immunocytochemistry; human; 1:100; fig 4
Skowron zwarg M, Boland S, Caruso N, Coraux C, Marano F, Tournier F. Interleukin-13 interferes with CFTR and AQP5 expression and localization during human airway epithelial cell differentiation. Exp Cell Res. 2007;313:2695-702 pubmed
  • immunohistochemistry - paraffin section; chicken; 1:1000
Cai Z, Blumbergs P, Finnie J, Manavis J, Thompson P. Novel fibroblastic onion bulbs in a demyelinating avian peripheral neuropathy produced by riboflavin deficiency. Acta Neuropathol. 2007;114:187-94 pubmed
  • immunohistochemistry - frozen section; human; fig 2
Peltonen S, Riehokainen J, Pummi K, Peltonen J. Tight junction components occludin, ZO-1, and claudin-1, -4 and -5 in active and healing psoriasis. Br J Dermatol. 2007;156:466-72 pubmed
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 3
Endemann M, Bergmeister H, Bidmon B, Boehm M, Csaicsich D, Malaga Dieguez L, et al. Evidence for HSP-mediated cytoskeletal stabilization in mesothelial cells during acute experimental peritoneal dialysis. Am J Physiol Renal Physiol. 2007;292:F47-56 pubmed
  • immunocytochemistry; domestic rabbit; fig 3
  • western blot; domestic rabbit; fig 1
Akoyev V, Takemoto D. ZO-1 is required for protein kinase C gamma-driven disassembly of connexin 43. Cell Signal. 2007;19:958-67 pubmed
  • immunohistochemistry; human; 1:20; fig 5
Hajj R, Baranek T, Le Naour R, Lesimple P, Puchelle E, Coraux C. Basal cells of the human adult airway surface epithelium retain transit-amplifying cell properties. Stem Cells. 2007;25:139-48 pubmed
  • immunohistochemistry; human; 1:50; fig 1
Anstrom J, Thore C, Moody D, Brown W. Immunolocalization of tight junction proteins in blood vessels in human germinal matrix and cortex. Histochem Cell Biol. 2007;127:205-13 pubmed
  • immunocytochemistry; dogs; 1:250
Guezguez B, Vigneron P, Alais S, Jaffredo T, Gavard J, Mège R, et al. A dileucine motif targets MCAM-l cell adhesion molecule to the basolateral membrane in MDCK cells. FEBS Lett. 2006;580:3649-56 pubmed
  • western blot; domestic rabbit; 2 ug/ml; fig 1
Mandell K, Holley G, Parkos C, Edelhauser H. Antibody blockade of junctional adhesion molecule-A in rabbit corneal endothelial tight junctions produces corneal swelling. Invest Ophthalmol Vis Sci. 2006;47:2408-16 pubmed
  • immunohistochemistry; mouse; 4 ug/ml; fig 4
Ciolofan C, Li X, Olson C, Kamasawa N, Gebhardt B, Yasumura T, et al. Association of connexin36 and zonula occludens-1 with zonula occludens-2 and the transcription factor zonula occludens-1-associated nucleic acid-binding protein at neuronal gap junctions in rodent retina. Neuroscience. 2006;140:433-51 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:1000
Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, et al. Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex. Development. 2006;133:1735-44 pubmed
  • immunoprecipitation; rat; tbl 1
  • western blot; rat; tbl 1
Sarkar O, Xia W, Mruk D. Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions. J Cell Physiol. 2006;208:175-87 pubmed
  • immunohistochemistry - frozen section; mouse; 2.5 ug/ml
Hirose T, Karasawa M, Sugitani Y, Fujisawa M, Akimoto K, Ohno S, et al. PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains. Development. 2006;133:1389-98 pubmed
  • immunohistochemistry - paraffin section; mouse; 20 ug/ml; fig 3
Nguyen M, Rivera C, Griep A. Localization of PDZ domain containing proteins Discs Large-1 and Scribble in the mouse eye. Mol Vis. 2005;11:1183-99 pubmed
  • immunocytochemistry; mouse; 1:200
Hyenne V, Louvet Vallee S, El Amraoui A, Petit C, Maro B, Simmler M. Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesis. Dev Biol. 2005;287:180-91 pubmed
  • immunohistochemistry - frozen section; human
Pummi K, Aho H, Laato M, Peltonen J, Peltonen S. Tight junction proteins and perineurial cells in neurofibromas. J Histochem Cytochem. 2006;54:53-61 pubmed
  • immunocytochemistry; human; 1:100
  • western blot; human; 1:333; fig 5B
Slattery C, Campbell E, McMorrow T, Ryan M. Cyclosporine A-induced renal fibrosis: a role for epithelial-mesenchymal transition. Am J Pathol. 2005;167:395-407 pubmed
  • immunohistochemistry - frozen section; mouse; 4 ug/ml; fig 4
  • immunoprecipitation; human; fig 5
  • immunocytochemistry; human; 0.5 ug/ml; fig 4
Li X, Olson C, Lu S, Nagy J. Association of connexin36 with zonula occludens-1 in HeLa cells, betaTC-3 cells, pancreas, and adrenal gland. Histochem Cell Biol. 2004;122:485-98 pubmed
  • immunocytochemistry; human; fig 4
Zeng R, Li X, Gorodeski G. Estrogen abrogates transcervical tight junctional resistance by acceleration of occludin modulation. J Clin Endocrinol Metab. 2004;89:5145-55 pubmed
  • immunocytochemistry; rat; 1:500
  • immunocytochemistry; African green monkey; 1:500
Moeller M, Soofi A, Braun G, Li X, Watzl C, Kriz W, et al. Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization. EMBO J. 2004;23:3769-79 pubmed
  • immunohistochemistry; human; 1:100; fig 2
Pummi K, Heape A, Grenman R, Peltonen J, Peltonen S. Tight junction proteins ZO-1, occludin, and claudins in developing and adult human perineurium. J Histochem Cytochem. 2004;52:1037-46 pubmed
  • immunohistochemistry; mouse
Parker L, Schmidt M, Jin S, Gray A, Beis D, Pham T, et al. The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation. Nature. 2004;428:754-8 pubmed
  • immunohistochemistry; human; 1:100; fig 1
Slobodov G, Feloney M, Gran C, Kyker K, Hurst R, Culkin D. Abnormal expression of molecular markers for bladder impermeability and differentiation in the urothelium of patients with interstitial cystitis. J Urol. 2004;171:1554-8 pubmed
  • immunocytochemistry; mouse; fig 5
Watanabe T, Miyatani S, Katoh I, Kobayashi S, Ikawa Y. Expression of a novel secretory form (Crb1s) of mouse Crumbs homologue Crb1 in skin development. Biochem Biophys Res Commun. 2004;313:263-70 pubmed
  • immunocytochemistry; human
  • immunocytochemistry; bovine
  • immunocytochemistry; dogs
  • immunocytochemistry; African green monkey
Berryman M, Goldenring J. CLIC4 is enriched at cell-cell junctions and colocalizes with AKAP350 at the centrosome and midbody of cultured mammalian cells. Cell Motil Cytoskeleton. 2003;56:159-72 pubmed
  • immunohistochemistry; human; fig 1
Malminen M, Koivukangas V, Peltonen J, Karvonen S, Oikarinen A, Peltonen S. Immunohistological distribution of the tight junction components ZO-1 and occludin in regenerating human epidermis. Br J Dermatol. 2003;149:255-60 pubmed
  • western blot; rat; 1:100; fig 7
Lau A, Mruk D. Rab8B GTPase and junction dynamics in the testis. Endocrinology. 2003;144:1549-63 pubmed
  • immunohistochemistry - paraffin section; mouse; fig 3
Manabe N, Hirai S, Imai F, Nakanishi H, Takai Y, Ohno S. Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells. Dev Dyn. 2002;225:61-9 pubmed
  • immunocytochemistry; human; 1:1000
Tavelin S, Gråsjö J, Taipalensuu J, Ocklind G, Artursson P. Applications of epithelial cell culture in studies of drug transport. Methods Mol Biol. 2002;188:233-72 pubmed
  • immunohistochemistry - paraffin section; human; fig 2
  • western blot; human; fig 1
Pummi K, Malminen M, Aho H, Karvonen S, Peltonen J, Peltonen S. Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin and in vitro differentiating keratinocytes. J Invest Dermatol. 2001;117:1050-8 pubmed
Johansson J, Karema Jokinen V, Hakanen S, Jylhä A, Uusitalo H, Vihinen Ranta M, et al. Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium. BMC Biol. 2019;17:63 pubmed publisher
Huang Y, Wang Y, Feng Y, Wang P, He X, Ren H, et al. Role of Endoplasmic Reticulum Stress-Autophagy Axis in Severe Burn-Induced Intestinal Tight Junction Barrier Dysfunction in Mice. Front Physiol. 2019;10:606 pubmed publisher
Lee T, Hsieh S, Chiang H. Fibronectin inhibitor pUR4 attenuates tumor necrosis factor α-induced endothelial hyperpermeability by modulating β1 integrin activation. J Biomed Sci. 2019;26:37 pubmed publisher
Hoffman S, Aviv Cohen N, Carroll I, Tulchinsky H, Borovok I, Dotan I, et al. Faecal Proteases from Pouchitis Patients Activate Protease Activating Receptor-2 to Disrupt the Epithelial Barrier. J Crohns Colitis. 2019;13:1558-1568 pubmed publisher
Cora V, Haderspeck J, Antkowiak L, Mattheus U, Neckel P, Mack A, et al. A Cleared View on Retinal Organoids. Cells. 2019;8: pubmed publisher
Kujawski S, Sonawane M, Knust E. penner/lgl2 is required for the integrity of the photoreceptor layer in the zebrafish retina. Biol Open. 2019;8: pubmed publisher
Desban L, Prendergast A, Roussel J, Rosello M, Geny D, Wyart C, et al. Regulation of the apical extension morphogenesis tunes the mechanosensory response of microvilliated neurons. PLoS Biol. 2019;17:e3000235 pubmed publisher
Chen A, Dong J, Yuan X, Bo H, Li S, Wang C, et al. Anti-H7N9 avian influenza A virus activity of interferon in pseudostratified human airway epithelium cell cultures. Virol J. 2019;16:44 pubmed publisher
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Zhang J, Termglinchan V, Shao N, Itzhaki I, Liu C, Ma N, et al. A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles. Cell Stem Cell. 2019;24:802-811.e5 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
ZO-1 Monoclonal Antibody (ZO1-1A12)
Catalog # :
33-9100
Quantity :
100µg
Price :
US 344.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Canine, Human, Rhesus Monkey
Applications :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5-10 µg/mL, Immunofluorescence: 5-10 µg/mL, Western Blot: 1-2 µg/mL
Species :
Canine, Human, Rhesus Monkey
Clone :
ZO1-1A12
Isotype :
IgG1
Storage :
-20°C
Description :
ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
Immunogen :
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
Format :
Liquid
Applications w/Dilutions :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5-10 µg/mL, Immunofluorescence: 5-10 µg/mL, Western Blot: 1-2 µg/mL
Aliases :
BOS_20285; DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); Tight junction protein ZO-1; Tjp1; ZO1; ZO-1; zona occludens 1; Zona occludens protein 1; zonula occludens 1 protein; Zonula occludens protein 1
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA