p38 MAPK beta Monoclonal Antibody (P38-11A5) | Invitrogen 33-8700 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

p38 MAPK beta Monoclonal Antibody (P38-11A5)

catalog :

33-8700

quantity :

100 µg

price :

US 449.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P38-11A5

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation

more info or order :

Invitrogen product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; loading ...; fig 2a	Hayakawa M, Hayakawa H, Petrova T, Ritprajak P, Sutavani R, Jiménez Andrade G, et al. Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction. J Biol Chem. 2017;292:1762-1772 pubmed publisher
western blot; mouse; fig 4	Caballero Franco C, Guma M, Choo M, Sano Y, Enzler T, Karin M, et al. Epithelial Control of Gut-Associated Lymphoid Tissue Formation through p38?-Dependent Restraint of NF-?B Signaling. J Immunol. 2016;196:2368-76 pubmed publisher
western blot; human; fig 2	Lee J, Kim J, Im Y, Seong G, Lee H. Cyclosporine A induces nerve growth factor expression via activation of MAPK p38 and NFAT5. Cornea. 2011;30 Suppl 1:S19-24 pubmed publisher
western blot; human; fig 3	Rasheed Z, Akhtar N, Haqqi T. Pomegranate extract inhibits the interleukin-1?-induced activation of MKK-3, p38?-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes. Arthritis Res Ther. 2010;12:R195 pubmed publisher
western blot; human	Martindale J, Wall J, Martinez Longoria D, Aryal P, Rockman H, Guo Y, et al. Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo. J Biol Chem. 2005;280:669-76 pubmed
	Zhao Q, Li C, Yu M, Sun Y, Wang J, Ma L, et al. HuR stabilizes HTT mRNA via interacting with its exon 11 in a mutant HTT-dependent manner. RNA Biol. 2020;17:500-516 pubmed publisher
	Cook B, Rafiq R, Lee H, Banks K, El Debs M, Chiaravalli J, et al. Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β. Cell Chem Biol. 2019;: pubmed publisher
	Yu M, Fu Y, Liang Y, Song H, Yao Y, Wu P, et al. Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models. Cell Res. 2017;27:1441-1465 pubmed publisher
	Risco A, del Fresno C, Mambol A, Alsina Beauchamp D, MacKenzie K, Yang H, et al. p38? and p38? kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation. Proc Natl Acad Sci U S A. 2012;109:11200-5 pubmed publisher
	Kuma Y, Sabio G, Bain J, Shpiro N, Marquez R, Cuenda A. BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo. J Biol Chem. 2005;280:19472-9 pubmed
	Williamson A, Dibling B, Boyne J, Selby P, Burchill S. Basic fibroblast growth factor-induced cell death is effected through sustained activation of p38MAPK and up-regulation of the death receptor p75NTR. J Biol Chem. 2004;279:47912-28 pubmed
	Schulz R, Aker S, Belosjorow S, Konietzka I, Rauen U, Heusch G. Stress kinase phosphorylation is increased in pacing-induced heart failure in rabbits. Am J Physiol Heart Circ Physiol. 2003;285:H2084-90 pubmed
	Rausch O, Marshall C. Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation. J Biol Chem. 1999;274:4096-105 pubmed

product information

Product Type :

Antibody

Product Name :

p38 MAPK beta Monoclonal Antibody (P38-11A5)

Catalog # :

33-8700

Quantity :

100 µg

Price :

US 449.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Human, Mouse

Clone :

P38-11A5

Isotype :

IgG1/IgG2a

Storage :

-20°C

Description :

Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

Immunogen :

Recombinant, full-length human p38 beta-2; the product of the p38-beta gene

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

MAP kinase 11; MAP kinase p38 beta; MAPK 11; Mapk11; mitogen activated protein kinase 11; mitogen-activated protein kinase 11; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; OTTHUMP00000196655; p38-2; P38b; p38beta; P38BETA2; Prkm11; protein kinase, mitogen activated kinase, 11, p38beta; SAPK2; SAPK2b; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b

more info or order :

Invitrogen product webpage