Cytochrome C Monoclonal Antibody (6H2.B4) | Invitrogen 33-8200 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytochrome C Monoclonal Antibody (6H2.B4)

catalog :

33-8200

quantity :

100 µg

price :

US 449.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6H2.B4

reactivity :

human, mouse, rat, chicken, fruit fly

application :

ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - free floating section

more info or order :

Invitrogen product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:25; loading ...; fig s5a	Takaki T, Montagner M, Serres M, Le Berre M, Russell M, Collinson L, et al. Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun. 2017;8:16013 pubmed publisher
immunocytochemistry; human; 1:1000; fig 2	Trimmer P, Borland M, Keeney P, Bennett J, Parker W. Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies. J Neurochem. 2004;88:800-12 pubmed
immunohistochemistry - free floating section; chicken	Wilkinson B, Elam J, Fadool D, Hyson R. Afferent regulation of cytochrome-c and active caspase-9 in the avian cochlear nucleus. Neuroscience. 2003;120:1071-9 pubmed
	Panier S, Maric M, Hewitt G, Mason Osann E, Gali H, Dai A, et al. SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance. Mol Cell. 2019;76:27-43.e11 pubmed publisher
	Martins I, Raza S, Voisin L, Dakhli H, Allouch A, Law F, et al. Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death. Cell Death Dis. 2018;9:716 pubmed publisher
	Jeong J, Chang J, Jo Y. Intracellular glycolysis in brown adipose tissue is essential for optogenetically induced nonshivering thermogenesis in mice. Sci Rep. 2018;8:6672 pubmed publisher
	Lahuerta M, Aguado C, Sánchez Martín P, Sanz P, Knecht E. Degradation of altered mitochondria by autophagy is impaired in Lafora disease. FEBS J. 2018;285:2071-2090 pubmed publisher
	Pease Raissi S, Pazyra Murphy M, Li Y, Wachter F, Fukuda Y, Fenstermacher S, et al. Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration. Neuron. 2017;96:373-386.e6 pubmed publisher
	FernÃ¡ndez SÃ¡nchez L, de Sevilla MÃ¼ller L, Brecha N, Cuenca N. Loss of outer retinal neurons and circuitry alterations in the DBA/2J mouse. Invest Ophthalmol Vis Sci. 2014;55:6059-72 pubmed publisher
	Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier C, et al. PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J Cell Biol. 2010;189:211-21 pubmed publisher
	Love D, Kochan J, Cathey R, Shin S, Hanover J, Kochran J. Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase. J Cell Sci. 2003;116:647-54 pubmed
	Sinai A, Joiner K. The Toxoplasma gondii protein ROP2 mediates host organelle association with the parasitophorous vacuole membrane. J Cell Biol. 2001;154:95-108 pubmed
	Nesterov A, Lu X, Johnson M, Miller G, Ivashchenko Y, Kraft A. Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis. J Biol Chem. 2001;276:10767-74 pubmed

product information

Product Type :

Antibody

Product Name :

Cytochrome C Monoclonal Antibody (6H2.B4)

Catalog # :

33-8200

Quantity :

100 µg

Price :

US 449.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Drosophila, Human, Mouse, Rabbit, Rat

Applications :

ELISA: 0.1-1 µg/mL, Immunocytochemistry: 5-20 µg/mL, Immunoprecipitation: 15 µg

Species :

Drosophila, Human, Mouse, Rabbit, Rat

Clone :

6H2.B4

Isotype :

IgG1, kappa

Storage :

Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Description :

Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.

Immunogen :

Rat Cytochrome C.

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.1-1 µg/mL, Immunocytochemistry: 5-20 µg/mL, Immunoprecipitation: 15 µg

Aliases :

CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4

more info or order :

Invitrogen product webpage