H-Ras Monoclonal Antibody (Y13-259) | Invitrogen 33-7200 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

H-Ras Monoclonal Antibody (Y13-259)

catalog :

33-7200

quantity :

50 ug

price :

US 520.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

Y13-259

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, other

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
other; mouse; loading ...; fig 2a	Riecken L, Zoch A, Wiehl U, Reichert S, Scholl I, Cui Y, et al. CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins. Oncotarget. 2016;7:78242-78254 pubmed publisher
immunoprecipitation; mouse; fig 4	Tian W, Boss G, Cohen D. Ras signaling in the inner medullary cell response to urea and NaCl. Am J Physiol Cell Physiol. 2000;278:C372-80 pubmed
	Gapuzan M, Schmah O, Pollock A, Hoffmann A, Gilmore T. Immortalized fibroblasts from NF-kappaB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor alpha after transformation by v-Ras. Oncogene. 2005;24:6574-83 pubmed
	Hodgson L, Henderson A, Dong C. Melanoma cell migration to type IV collagen requires activation of NF-kappaB. Oncogene. 2003;22:98-108 pubmed

product information

Product Type :

Antibody

Product Name :

H-Ras Monoclonal Antibody (Y13-259)

Catalog # :

33-7200

Quantity :

50 ug

Price :

US 520.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Human, Mouse, Rat

Clone :

Y13-259

Isotype :

IgG1, kappa

Storage :

-20 C

Description :

Monomeric G protein Ras functions as a molecular switch linking receptor and nonreceptor tyrosine kinase activation to a number of downstream signaling pathways leading to distinct cytoplasmic or nuclear events. Each mammalian cell contains three Ras proto-oncogene coding for closely related Ras proteins: H-, K-, N-Ras. Oncogenic mutations in Ras genes are present in ~30% of all human cancers. Constitutive activation of Ras due to mutations or overexpression stimulates proliferation and inhibition of apoptosis. K-Ras mutations are common in pancreatic, colorectal and nonsmall-cell lung carcinomas; H-Ras mutations are common in bladder, kidney and thyroid carcinomas; N-Ras mutations are found in melanoma, hematological malignancies and hepatocellular carcinaoma.

Immunogen :

Recombinant p21 ras protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

C-BAS/HAS; c-Ha-ras; c-Ha-ras p21 protein; c-Ha-ras transgene; C-HA-RAS1; c-has/bas p21 protein; c-H-ras; c-rasHa; c-ras-Ki-2 activated oncogene; CTLO; GTP- and GDP-binding peptide B; GTPase HRas; GTPase HRas, N-terminally processed; GTPase Hras1; HAMSV; Ha-ras; Ha-Ras1 proto-oncoprotein; Harvey ras1 protein; Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog; Harvey rat sarcoma viral oncogene homolog; Harvey rat sarcoma viral oncoprotein; Harvey rat sarcoma virus oncogene; Harvey rat sarcoma virus oncogene 1; Harvey-ras; Hras; H-ras; H-ras 1 protein; HRas proto-oncogene, GTPase; HRAS1; H-Ras-1; Hras-1; H-RASIDX; Kras2; p19 H-RasIDX protein; p21ras; ras; Ras family small GTP binding protein H-Ras; ras p21; RASH1; transformation gene: oncogene HAMSV; transforming protein P21; v-Ha-ras Harvey rat sarcoma viral oncogene homolog

more info or order :

Invitrogen product webpage