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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD44v6 Monoclonal Antibody (MA54)
catalog :
33-6700
quantity :
100 ug
price :
US 471.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MA54
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig s1b, s1c
Nunes M, Pacheco F, Coelho R, Leit xe3 o D, Ricardo S, David L. Mesothelin Expression Is Not Associated with the Presence of Cancer Stem Cell Markers SOX2 and ALDH1 in Ovarian Cancer. Int J Mol Sci. 2022;23: pubmed publisher
  • immunocytochemistry; human; 1:5
  • immunohistochemistry; human; 1:50
Campos D, Freitas D, Gomes J, Magalhães A, Steentoft C, Gomes C, et al. Probing the O-glycoproteome of gastric cancer cell lines for biomarker discovery. Mol Cell Proteomics. 2015;14:1616-29 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50
Chen K, Li Z, Jiang P, Zhang X, Zhang Y, Jiang Y, et al. Co-expression of CD133, CD44v6 and human tissue factor is associated with metastasis and poor prognosis in pancreatic carcinoma. Oncol Rep. 2014;32:755-63 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 3
  • immunohistochemistry; human; 1:200; fig 4
da Cunha C, Oliveira C, Wen X, Gomes B, Sousa S, Suriano G, et al. De novo expression of CD44 variants in sporadic and hereditary gastric cancer. Lab Invest. 2010;90:1604-14 pubmed publisher
Ognibene M, Pezzolo A. Roniciclib down-regulates stemness and inhibits cell growth by inducing nucleolar stress in neuroblastoma. Sci Rep. 2020;10:12902 pubmed publisher
Mereiter S, Martins x, Gomes C, Balma xf1 a M, Macedo J, Polom K, et al. O-glycan truncation enhances cancer-related functions of CD44 in gastric cancer. FEBS Lett. 2019;593:1675-1689 pubmed publisher
Angelucci C, Lama G, Iacopino F, Sica G. Leuprorelin acetate affects adhesion molecule expression in human prostate cancer cells. Int J Oncol. 2011;38:1501-9 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD44v6 Monoclonal Antibody (MA54)
Catalog # :
33-6700
Quantity :
100 ug
Price :
US 471.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Immunocytochemistry: 2 ug/mL, Immunohistochemistry: Assay-dependent, Western Blot: 2 ug/mL
Species :
Human
Clone :
MA54
Isotype :
IgG1
Storage :
-20 C
Description :
CD44 cell surface antigen is a 100kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.
Immunogen :
epitope encoded by exon v6 on the variant portion of human CD44
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2 ug/mL, Immunohistochemistry: Assay-dependent, Western Blot: 2 ug/mL
Aliases :
AL133330.1; AU023126; AW121933; AW146109; CD44; CD44 antigen; CD44 molecule (Indian blood group); CD44 splice variant; CD44 V6; CD44 var; CD44 variant; CD44v6; CD44var (v6); CDW44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCHI; HUTCH-I; Hyaluronate receptor; IN; LHR; Ly-24; Lymphocyte antigen 24; MC56; MDU2; MDU3; MGC10468; MIC4; MUTCH-I; PGP I; Pgp1; Pgp-1; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; soluble CD44
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA