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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Phospho-STAT5 beta (Tyr694) Monoclonal Antibody (ST5P-4A9)
catalog :
33-6000
quantity :
50 µg
price :
US 430.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
ST5P-4A9
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA
more info or order :
Invitrogen product webpage
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:500
Bennett E, McGuinness L, Gevers E, Thomas G, Robinson I, Davey H, et al. Hypothalamic STAT proteins: regulation of somatostatin neurones by growth hormone via STAT5b. J Neuroendocrinol. 2005;17:186-94 pubmed
  • western blot; human; fig 2
Duensing A, Medeiros F, McConarty B, Joseph N, Panigrahy D, Singer S, et al. Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs). Oncogene. 2004;23:3999-4006 pubmed
Moriguchi M, Hissong B, Gadina M, Yamaoka K, Tiffany H, Murphy P, et al. CXCL12 signaling is independent of Jak2 and Jak3. J Biol Chem. 2005;280:17408-14 pubmed
Gewinner C, Hart G, Zachara N, Cole R, Beisenherz Huss C, Groner B. The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5. J Biol Chem. 2004;279:3563-72 pubmed
Chong M, Cornish A, Darwiche R, Stanley E, Purton J, Godfrey D, et al. Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation. Immunity. 2003;18:475-87 pubmed
product information
Product Type :
Antibody
Product Name :
Phospho-STAT5 beta (Tyr694) Monoclonal Antibody (ST5P-4A9)
Catalog # :
33-6000
Quantity :
50 µg
Price :
US 430.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Bovine, Human, Mouse, Ovine, Rat
Applications :
ELISA: Assay-dependent, Western Blot: Assay-dependent
Species :
Bovine, Human, Mouse, Ovine, Rat
Clone :
ST5P-4A9
Isotype :
IgG1, kappa
Storage :
-20°C
Description :
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Immunogen :
A synthetic tyrosine phosphorylated peptide encompassing the conserved C-terminal tyrosine phosphorylation site (Y694) of murine STAT5. This peptide is conserved in human, bovine, sheep, and rat STAT5 proteins
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Western Blot: Assay-dependent
Aliases :
LOC101122961; mammary gland factor STAT5B; Signal transducer and activator of transcription 5a; signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; STAT5B; transcription factor STAT5B
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA