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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GAP43 Monoclonal Antibody (7B10)
catalog :
33-5000
quantity :
100 µg
price :
US 402.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7B10
reactivity :
human, mouse, rat, chicken, domestic rabbit
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:2000; fig 6
Madinier A, Bertrand N, Mossiat C, Prigent Tessier A, Beley A, Marie C, et al. Microglial involvement in neuroplastic changes following focal brain ischemia in rats. PLoS ONE. 2009;4:e8101 pubmed publisher
  • immunohistochemistry; mouse; fig 3
Watanabe Y, Inoue K, Okuyama Yamamoto A, Nakai N, Nakatani J, Nibu K, et al. Fezf1 is required for penetration of the basal lamina by olfactory axons to promote olfactory development. J Comp Neurol. 2009;515:565-84 pubmed publisher
  • immunohistochemistry - paraffin section; domestic rabbit; 1:500; fig 4
Kazuo Ikeda K, Masaki Matsuda M, Daisuke Yamauchi D, Katsuro Tomita K, Shigenori Tanaka S. Gradual nerve elongation affects nerve cell bodies and neuro-muscular junctions. Hand Surg. 2005;10:7-15 pubmed
  • immunohistochemistry; mouse
Xu P, Yoshioka K, Yoshimura D, Tominaga Y, Nishioka T, Ito M, et al. In vitro development of mouse embryonic stem cells lacking JNK/stress-activated protein kinase-associated protein 1 (JSAP1) scaffold protein revealed its requirement during early embryonic neurogenesis. J Biol Chem. 2003;278:48422-33 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 3
Seitz A, Aglow E, Heber Katz E. Recovery from spinal cord injury: a new transection model in the C57Bl/6 mouse. J Neurosci Res. 2002;67:337-45 pubmed
Chen Y, Tsai M, Hsieh N, Lo M, Lee M, Cheng H, et al. The superiority of conditioned medium derived from rapidly expanded mesenchymal stem cells for neural repair. Stem Cell Res Ther. 2019;10:390 pubmed publisher
Chen C, Tsai M, Lin C, Yu I, Chen Y, Lin S, et al. Rescue of the genetically engineered Cul4b mutant mouse as a potential model for human X-linked mental retardation. Hum Mol Genet. 2012;21:4270-85 pubmed publisher
Miyoshi K, Akazawa Y, Horiguchi T, Noma T. Localization of adenylate kinase 4 in mouse tissues. Acta Histochem Cytochem. 2009;42:55-64 pubmed publisher
Gustincich S, Contini M, Gariboldi M, Puopolo M, Kadota K, Bono H, et al. Gene discovery in genetically labeled single dopaminergic neurons of the retina. Proc Natl Acad Sci U S A. 2004;101:5069-74 pubmed
Baltensperger K, Kozma L, Cherniack A, Klarlund J, Chawla A, Banerjee U, et al. Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes. Science. 1993;260:1950-2 pubmed
product information
Product Type :
Antibody
Product Name :
GAP43 Monoclonal Antibody (7B10)
Catalog # :
33-5000
Quantity :
100 µg
Price :
US 402.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Chicken, Human, Mouse, Rabbit, Rat, Reptile
Applications :
ELISA: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
Species :
Chicken, Human, Mouse, Rabbit, Rat, Reptile
Clone :
7B10
Isotype :
IgG2a, kappa
Storage :
-20°C
Description :
GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile "growth cones" that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.
Immunogen :
Purified, full length GAP-43 protein (both phosphorylated & unphosphorylated forms).
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
Aliases :
Axonal membrane protein GAP-43; B-50; Basp2; brain abundant, membrane attached signal protein 2; calmodulin-binding protein P-57; Gap43; GAP-43; growth accentuating protein 43; growth associated protein 43; growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; PP46; Protein F1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA