SRSF3 Monoclonal Antibody (7B4 (7B4A12)) | Invitrogen 33-4200 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SRSF3 Monoclonal Antibody (7B4 (7B4A12))

catalog :

33-4200

quantity :

100 µg

price :

US 449.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7B4 (7B4A12)

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, cross-linking immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:100; fig 3 western blot; human; 1:250; fig 2	Klymenko T, Hernández López H, MacDonald A, Bodily J, Graham S. Human Papillomavirus E2 Regulates SRSF3 (SRp20) To Promote Capsid Protein Expression in Infected Differentiated Keratinocytes. J Virol. 2016;90:5047-58 pubmed publisher
immunohistochemistry - paraffin section; human; 1:300; loading ...; tbl s2	Cammas A, Lacroix Triki M, Pierredon S, Le Bras M, Iacovoni J, Teulade Fichou M, et al. hnRNP A1-mediated translational regulation of the G quadruplex-containing RON receptor tyrosine kinase mRNA linked to tumor progression. Oncotarget. 2016;7:16793-805 pubmed publisher
western blot; human; fig 1	Park S, Jeong S. SRSF3 represses the expression of PDCD4 protein by coordinated regulation of alternative splicing, export and translation. Biochem Biophys Res Commun. 2016;470:431-438 pubmed publisher
cross-linking immunoprecipitation; human; fig 4	Martinez N, Agosto L, Qiu J, Mallory M, Gazzara M, Barash Y, et al. Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Genes Dev. 2015;29:2054-66 pubmed publisher
immunohistochemistry; rat; 1:500; fig 6	Li S, Li Y, Cui S, Qi Y, Zhao J, Liu X, et al. Splicing factor transformer-2? (Tra2?) regulates the expression of regulator of G protein signaling 4 (RGS4) gene and is induced by morphine. PLoS ONE. 2013;8:e72220 pubmed publisher
immunocytochemistry; human; fig 5	Wong R, Balachandran A, Haaland M, Stoilov P, Cochrane A. Characterization of novel inhibitors of HIV-1 replication that function via alteration of viral RNA processing and rev function. Nucleic Acids Res. 2013;41:9471-83 pubmed publisher
	Ha J, Jang H, Choi N, Oh J, Min C, Pradella D, et al. SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon. Cells. 2021;10: pubmed publisher
	Ben C, Wu X, Takahashi Kanemitsu A, Knight C, Hayashi T, Hatakeyama M. Alternative splicing reverses the cell-intrinsic and cell-extrinsic pro-oncogenic potentials of YAP1. J Biol Chem. 2020;295:13965-13980 pubmed publisher
	Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa M, Uriarte I, et al. Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins. Nucleic Acids Res. 2019;47:3450-3466 pubmed publisher
	Meyer C, Garzia A, Mazzola M, Gerstberger S, Molina H, Tuschl T. The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression. Mol Cell. 2018;69:622-635.e6 pubmed publisher
	Jia R, Zhang S, Liu M, Zhang Y, Liu Y, Fan M, et al. HnRNP L is important for the expression of oncogene SRSF3 and oncogenic potential of oral squamous cell carcinoma cells. Sci Rep. 2016;6:35976 pubmed publisher
	Wong R, Balachandran A, Ostrowski M, Cochrane A. Digoxin suppresses HIV-1 replication by altering viral RNA processing. PLoS Pathog. 2013;9:e1003241 pubmed publisher
	Anderson E, Lin C, Xiao X, Stoilov P, Burge C, Black D. The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B. RNA. 2012;18:1041-9 pubmed publisher
	Li J, Hawkins I, Harvey C, Jennings J, Link A, Patton J. Regulation of alternative splicing by SRrp86 and its interacting proteins. Mol Cell Biol. 2003;23:7437-47 pubmed
	Huang Y, Gattoni R, Stevenin J, Steitz J. SR splicing factors serve as adapter proteins for TAP-dependent mRNA export. Mol Cell. 2003;11:837-43 pubmed
	Sciabica K, Dai Q, Sandri Goldin R. ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation. EMBO J. 2003;22:1608-19 pubmed

product information

Product Type :

Antibody

Product Name :

SRSF3 Monoclonal Antibody (7B4 (7B4A12))

Catalog # :

33-4200

Quantity :

100 µg

Price :

US 449.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: 2 µg/mL

Species :

Human

Clone :

7B4 (7B4A12)

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

SR proteins appear to be recruited from nuclear "speckles", in which they are concentrated, to sites of transcription in order to spatially coordinate transcription and pre-mRNA splicing within the cell nucleus.

Immunogen :

A synthetic peptide corresponding to amino acids 84-104 of the human SRp20 protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: 2 µg/mL

Aliases :

AL024116; pre-mRNA splicing factor SRp20; pre-mRNA-splicing factor SRP20; Protein X16; serine and arginine rich splicing factor 3; serine/arginine-rich splicing factor 3; SFRS3; splicing factor, arginine/serine-rich 3; splicing factor, arginine/serine-rich 3 (SRp20); splicing factor, arginine/serine-rich, 20-kD; Srp20; SRSF3; X16

more info or order :

Invitrogen product webpage