product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
N-cadherin Monoclonal Antibody (3B9)
catalog :
33-3900
quantity :
100 ug
price :
US 496.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3B9
reactivity :
African green monkey, human, mouse, rat, dogs, chicken, pigs , domestic rabbit, domestic horse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 235
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3
Sugita J, Fujiu K, Nakayama Y, Matsubara T, Matsuda J, Oshima T, et al. Cardiac macrophages prevent sudden death during heart stress. Nat Commun. 2021;12:1910 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; tbl 2
Christgen M, Bartels S, van Luttikhuizen J, Bublitz J, Rieger L, Christgen H, et al. E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements. Mod Pathol. 2020;33:2483-2498 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 4h
Kim K, Shin W, Kang M, Lee S, Kim D, Kang R, et al. Presynaptic PTPσ regulates postsynaptic NMDA receptor function through direct adhesion-independent mechanisms. elife. 2020;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6d
Lubbers E, Murphy N, Musa H, Huang C, Gupta R, Price M, et al. Defining new mechanistic roles for αII spectrin in cardiac function. J Biol Chem. 2019;294:9576-9591 pubmed publisher
  • immunocytochemistry; mouse; 1:250; loading ...; fig 1a
Li Y, Merkel C, Zeng X, Heier J, Cantrell P, Sun M, et al. The N-cadherin interactome in primary cardiomyocytes as defined using quantitative proximity proteomics. J Cell Sci. 2019;132: pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3a
Gemel J, Su Z, Gileles Hillel A, Khalyfa A, Gozal D, Beyer E. Intermittent hypoxia causes NOX2-dependent remodeling of atrial connexins. BMC Cell Biol. 2017;18:7 pubmed publisher
  • immunohistochemistry; rat; loading ...; fig 7b
Maltabe V, Barka E, Kontonika M, Florou D, Kouvara Pritsouli M, Roumpi M, et al. Isolation of an ES-Derived Cardiovascular Multipotent Cell Population Based on VE-Cadherin Promoter Activity. Stem Cells Int. 2016;2016:8305624 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 3b
Le Dour C, Macquart C, Sera F, Homma S, Bonne G, Morrow J, et al. Decreased WNT/?-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene. Hum Mol Genet. 2017;26:333-343 pubmed publisher
  • immunohistochemistry; mouse; loading ...
Ma H, Wang L, Liu J, Qian L. Direct Cardiac Reprogramming as a Novel Therapeutic Strategy for Treatment of Myocardial Infarction. Methods Mol Biol. 2017;1521:69-88 pubmed
  • immunocytochemistry; rat; 1:200; loading ...; fig 3a
  • western blot; rat; 1:200; loading ...; fig 3a
Gao Y, Mruk D, Chen H, Lui W, Lee W, Cheng C. Regulation of the blood-testis barrier by a local axis in the testis: role of laminin ?2 in the basement membrane. FASEB J. 2017;31:584-597 pubmed publisher
  • western blot; human; loading ...; fig 4b
Polusani S, Kalmykov E, Chandrasekhar A, Zucker S, Nicholson B. Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration. J Cell Sci. 2016;129:4399-4410 pubmed
  • immunocytochemistry; human; loading ...; fig 3c
Lobato Álvarez J, Roldán M, López Murillo T, González Ramírez R, Bonilla Delgado J, Shoshani L. The Apical Localization of Na+, K+-ATPase in Cultured Human Retinal Pigment Epithelial Cells Depends on Expression of the ?2 Subunit. Front Physiol. 2016;7:450 pubmed
  • immunocytochemistry; human; loading ...; fig 5c
  • western blot; human; loading ...; fig 5c
Matos M, Lapyckyj L, Rosso M, Besso M, Mencucci M, Briggiler C, et al. Identification of a Novel Human E-Cadherin Splice Variant and Assessment of Its Effects Upon EMT-Related Events. J Cell Physiol. 2017;232:1368-1386 pubmed publisher
  • immunocytochemistry; rat; 1:100; loading ...; tbl 1
  • western blot; rat; 1:500; loading ...; tbl 1
Li N, Lee W, Cheng C. Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier. Spermatogenesis. 2016;6:e1206353 pubmed publisher
  • immunocytochemistry; rat; 1:100; fig 1
  • western blot; rat; 1:500; fig 1
Li N, Mruk D, Chen H, Wong C, Lee W, Cheng C. Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43. Sci Rep. 2016;6:29667 pubmed publisher
  • immunohistochemistry; human; loading ...
Grassi M, Palma C, Thomé C, Lanfredi G, Poersch A, Faça V. Proteomic analysis of ovarian cancer cells during epithelial-mesenchymal transition (EMT) induced by epidermal growth factor (EGF) reveals mechanisms of cell cycle control. J Proteomics. 2017;151:2-11 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100; fig 2
  • immunocytochemistry; rat; 1:100; fig 5
  • western blot; rat; 1:200; fig 5
Gao Y, Lui W, Lee W, Cheng C. Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells. Sci Rep. 2016;6:28589 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig s3
De Cian M, Pauper E, Bandiera R, Vidal V, Sacco S, Gregoire E, et al. Amplification of R-spondin1 signaling induces granulosa cell fate defects and cancers in mouse adult ovary. Oncogene. 2017;36:208-218 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 3
Zhang H, Prado K, Zhang K, Peek E, Lee J, Wang X, et al. Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance. Clin Cancer Res. 2016;22:5349-5361 pubmed
  • immunoprecipitation; rat; 1:60; fig 2
  • immunocytochemistry; rat; 1:100; fig 1
  • western blot; rat; 1:200; fig 3
Chen H, Mruk D, Lee W, Cheng C. Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats. Endocrinology. 2016;157:2140-59 pubmed publisher
  • immunocytochemistry; rat; 1:100; fig 1
Chojnacka K, Bilinska B, Mruk D. Interleukin 1alpha-induced disruption of the Sertoli cell cytoskeleton affects gap junctional communication. Cell Signal. 2016;28:469-480 pubmed publisher
  • western blot; mouse; 1:100; tbl 1
Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
  • western blot; human; fig 5
Little E, Camp E, Wang C, Watson P, Watson D, Cole D. The CaSm (LSm1) oncogene promotes transformation, chemoresistance and metastasis of pancreatic cancer cells. Oncogenesis. 2016;5:e182 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100; tbl 2
Li N, Mruk D, Mok K, Li M, Wong C, Lee W, et al. Connexin 43 reboots meiosis and reseals blood-testis barrier following toxicant-mediated aspermatogenesis and barrier disruption. FASEB J. 2016;30:1436-52 pubmed publisher
  • western blot; mouse; fig 7
Bhate A, Parker D, Bebee T, Ahn J, Arif W, Rashan E, et al. ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation. Nat Commun. 2015;6:8768 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:150; fig 1b
McCart Reed A, Kutasovic J, Vargas A, Jayanthan J, Al Murrani A, Reid L, et al. An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas. J Pathol. 2016;238:489-94 pubmed publisher
  • western blot; African green monkey
  • western blot; rat; 1:1000
Nassal M, Werdich A, Wan X, Hoshi M, Deschênes I, Rosenbaum D, et al. Phosphorylation at Connexin43 Serine-368 Is Necessary for Myocardial Conduction During Metabolic Stress. J Cardiovasc Electrophysiol. 2016;27:110-9 pubmed publisher
  • western blot; human; 1:500; fig 2a
Martínez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed publisher
  • western blot; human; 1:500; fig 3
Marchi S, Corricelli M, Trapani E, Bravi L, Pittaro A, Delle Monache S, et al. Defective autophagy is a key feature of cerebral cavernous malformations. EMBO Mol Med. 2015;7:1403-17 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500
Basheer W, Harris B, Mentrup H, Abreha M, Thames E, Lea J, et al. Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis. J Mol Cell Cardiol. 2015;88:1-13 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; tbl 3
Russell R, Perkhofer L, Liebau S, Lin Q, Lechel A, Feld F, et al. Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition. Nat Commun. 2015;6:7677 pubmed publisher
  • immunohistochemistry - paraffin section; domestic horse; 1:500
  • western blot; domestic horse; 1:500
Rode K, Sieme H, Richterich P, Brehm R. Characterization of the equine blood-testis barrier during tubular development in normal and cryptorchid stallions. Theriogenology. 2015;84:763-72 pubmed publisher
  • immunohistochemistry; rat; 1:100
Li N, Mruk D, Wong C, Lee W, Han D, Cheng C. Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis. FASEB J. 2015;29:3788-805 pubmed publisher
  • western blot; human; 1:1000
Liu S, Tetzlaff M, Wang T, Yang R, Xie L, Zhang G, et al. miR-200c/Bmi1 axis and epithelial-mesenchymal transition contribute to acquired resistance to BRAF inhibitor treatment. Pigment Cell Melanoma Res. 2015;28:431-41 pubmed publisher
  • western blot; human; 1:500
ORELLANA R, Kato S, Erices R, Bravo M, Gonzalez P, Oliva B, et al. Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells. BMC Cancer. 2015;15:290 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100
  • immunoprecipitation; rat
  • western blot; rat; 1:1000
Zarzycka M, Chojnacka K, Mruk D, Górowska E, Hejmej A, Kotula Balak M, et al. Flutamide alters the distribution of c-Src and affects the N-cadherin-β-catenin complex in the seminiferous epithelium of adult rat. Andrology. 2015;3:569-81 pubmed publisher
  • immunohistochemistry; rat; 1:200
Tennakoon A, Izawa T, Wijesundera K, Katou Ichikawa C, Tanaka M, Golbar H, et al. Analysis of glial fibrillary acidic protein (GFAP)-expressing ductular cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA). Exp Mol Pathol. 2015;98:476-85 pubmed publisher
  • immunohistochemistry; domestic rabbit; fig 4
  • western blot; domestic rabbit; fig 3
Kageyama T, Hayashi R, Hara S, Yoshikawa K, Ishikawa Y, Yamato M, et al. Spontaneous acquisition of infinite proliferative capacity by a rabbit corneal endothelial cell line with maintenance of phenotypic and physiological characteristics. J Tissue Eng Regen Med. 2017;11:1057-1064 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse
Knezevic J, Pfefferle A, Petrovic I, Greene S, Perou C, Rosen J. Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential. Oncogene. 2015;34:5997-6006 pubmed publisher
  • immunohistochemistry; mouse
Zhang J, Upadhya D, Lu L, Reneker L. Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development. PLoS ONE. 2015;10:e0117089 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:300
Davidson B, Holth A, Hellesylt E, Tan T, Huang R, Tropé C, et al. The clinical role of epithelial-mesenchymal transition and stem cell markers in advanced-stage ovarian serous carcinoma effusions. Hum Pathol. 2015;46:1-8 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Sun Y, Hu L, Zheng H, Bagnoli M, Guo Y, Rupaimoole R, et al. MiR-506 inhibits multiple targets in the epithelial-to-mesenchymal transition network and is associated with good prognosis in epithelial ovarian cancer. J Pathol. 2015;235:25-36 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100
  • western blot; rat; 1:125
Mok K, Mruk D, Cheng C. rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9. J Cell Sci. 2014;127:4870-82 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig s9a
Ye T, Ip J, Fu A, Ip N. Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex. Nat Commun. 2014;5:4826 pubmed publisher
  • western blot; rat; fig 6b
Kudo Sakamoto Y, Akazawa H, Ito K, Takano J, Yano M, Yabumoto C, et al. Calpain-dependent cleavage of N-cadherin is involved in the progression of post-myocardial infarction remodeling. J Biol Chem. 2014;289:19408-19 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 8a
Katanosaka Y, Iwasaki K, Ujihara Y, Takatsu S, Nishitsuji K, Kanagawa M, et al. TRPV2 is critical for the maintenance of cardiac structure and function in mice. Nat Commun. 2014;5:3932 pubmed publisher
  • immunohistochemistry; human; 1:500; fig 8
Sehgal L, Mukhopadhyay A, Rajan A, Khapare N, Sawant M, Vishal S, et al. 14-3-3?-Mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo. J Cell Sci. 2014;127:2174-88 pubmed publisher
  • western blot; human; 1:1000
Brueggmann D, Templeman C, Starzinski Powitz A, Rao N, Gayther S, Lawrenson K. Novel three-dimensional in vitro models of ovarian endometriosis. J Ovarian Res. 2014;7:17 pubmed publisher
  • immunohistochemistry - paraffin section; human
Fantozzi A, Gruber D, Pisarsky L, Heck C, Kunita A, Yilmaz M, et al. VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation. Cancer Res. 2014;74:1566-75 pubmed publisher
  • immunohistochemistry; human; 1:100; fig 9
Haisler W, Timm D, Gage J, Tseng H, Killian T, Souza G. Three-dimensional cell culturing by magnetic levitation. Nat Protoc. 2013;8:1940-9 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; tbl 1
Sjödahl G, Lövgren K, Lauss M, Patschan O, Gudjonsson S, Chebil G, et al. Toward a molecular pathologic classification of urothelial carcinoma. Am J Pathol. 2013;183:681-91 pubmed publisher
  • immunohistochemistry; rat; 1:100
Qian X, Mruk D, Cheng C. Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*. PLoS ONE. 2013;8:e60656 pubmed publisher
  • western blot; human; fig 4
Lee J, Mhawech Fauceglia P, Lee N, Parsanian L, Lin Y, Gayther S, et al. A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro. Lab Invest. 2013;93:528-42 pubmed publisher
  • immunohistochemistry; human; 1:150; fig 1
Rakha E, Teoh T, Lee A, Nolan C, Ellis I, Green A. Further evidence that E-cadherin is not a tumour suppressor gene in invasive ductal carcinoma of the breast: an immunohistochemical study. Histopathology. 2013;62:695-701 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Danielson L, Park D, Rotllan N, Chamorro Jorganes A, Guijarro M, Fernandez Hernando C, et al. Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis. FASEB J. 2013;27:1460-7 pubmed publisher
  • western blot; human; fig 3
Wang Q, Lin J, Chan S, Lin J. The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development. Dev Biol. 2013;374:264-80 pubmed publisher
  • western blot; human; fig 3
Tran M, Choi W, Wszolek M, Navai N, Lee I, Nitti G, et al. The p63 protein isoform ?Np63? inhibits epithelial-mesenchymal transition in human bladder cancer cells: role of MIR-205. J Biol Chem. 2013;288:3275-88 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100
Tang E, Xiao X, Mruk D, Qian X, Mok K, Jenardhanan P, et al. Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis. Spermatogenesis. 2012;2:117-126 pubmed
  • western blot; mouse; fig 4
Swope D, Li J, Muller E, Radice G. Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability. Genesis. 2012;50:717-27 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 3
Stoyianni A, Goussia A, Pentheroudakis G, Siozopoulou V, Ioachim E, Krikelis D, et al. Immunohistochemical study of the epithelial-mesenchymal transition phenotype in cancer of unknown primary: incidence, correlations and prognostic utility. Anticancer Res. 2012;32:1273-81 pubmed
  • western blot; mouse; fig 1
Swope D, Cheng L, Gao E, Li J, Radice G. Loss of cadherin-binding proteins ?-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis. Mol Cell Biol. 2012;32:1056-67 pubmed publisher
  • immunocytochemistry; mouse; fig 5
Schneider D, Wu M, Le T, Cho S, Brenner M, Blackburn M, et al. Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-? production and epithelial to mesenchymal transition. FASEB J. 2012;26:503-12 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
  • western blot; mouse
Maddala R, Chauhan B, Walker C, Zheng Y, Robinson M, Lang R, et al. Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev Biol. 2011;360:30-43 pubmed publisher
  • immunohistochemistry; human; 1:20
Saghizadeh M, Soleymani S, Harounian A, Bhakta B, Troyanovsky S, Brunken W, et al. Alterations of epithelial stem cell marker patterns in human diabetic corneas and effects of c-met gene therapy. Mol Vis. 2011;17:2177-90 pubmed
  • immunocytochemistry; human; 1:100; fig 4
Watanabe R, Hayashi R, Kimura Y, Tanaka Y, Kageyama T, Hara S, et al. A novel gelatin hydrogel carrier sheet for corneal endothelial transplantation. Tissue Eng Part A. 2011;17:2213-9 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:40; fig 5
Ferro F, Spelat R, Falini G, Gallelli A, D Aurizio F, Puppato E, et al. Adipose tissue-derived stem cell in vitro differentiation in a three-dimensional dental bud structure. Am J Pathol. 2011;178:2299-310 pubmed publisher
  • immunohistochemistry; mouse; fig 6
Li J, Swope D, Raess N, Cheng L, Muller E, Radice G. Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling. Mol Cell Biol. 2011;31:1134-44 pubmed publisher
  • western blot; human
Liu M, Sakamaki T, Casimiro M, Willmarth N, Quong A, Ju X, et al. The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion. Cancer Res. 2010;70:10464-73 pubmed publisher
  • immunoprecipitation; rat; fig 2
Palatinus J, O Quinn M, Barker R, Harris B, Jourdan J, Gourdie R. ZO-1 determines adherens and gap junction localization at intercalated disks. Am J Physiol Heart Circ Physiol. 2011;300:H583-94 pubmed publisher
  • immunohistochemistry; mouse; fig 5
Schoenauer R, Emmert M, Felley A, Ehler E, Brokopp C, Weber B, et al. EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy. Basic Res Cardiol. 2011;106:233-47 pubmed publisher
  • immunocytochemistry; rat; 1:50; tbl 1
Su L, Cheng C, Mruk D. Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo. Int J Biochem Cell Biol. 2010;42:1864-75 pubmed publisher
  • immunocytochemistry; rat; 1:50; tbl 1
  • western blot; rat; 1:250; tbl 1
Su L, Mruk D, Lee W, Cheng C. Differential effects of testosterone and TGF-?3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier. Exp Cell Res. 2010;316:2945-60 pubmed publisher
  • immunohistochemistry; human; 1:100; tbl 1
Flatmark K, Davidson B, Kristian A, Stavnes H, Førsund M, Reed W. Exploring the peritoneal surface malignancy phenotype--a pilot immunohistochemical study of human pseudomyxoma peritonei and derived animal models. Hum Pathol. 2010;41:1109-19 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; tbl 2
Kaarteenaho R, Sormunen R, Paakko P. Variable expression of tenascin-C, osteopontin and fibronectin in inflammatory myofibroblastic tumour of the lung. APMIS. 2010;118:91-100 pubmed publisher
  • immunohistochemistry; human; fig 3b
D Eliseo D, Pisu P, Romano C, Tubaro A, De Nunzio C, Morrone S, et al. Granzyme B is expressed in urothelial carcinoma and promotes cancer cell invasion. Int J Cancer. 2010;127:1283-94 pubmed publisher
  • western blot; human; 1:500; fig 6
Yiin J, Hu B, Jarzynka M, Feng H, Liu K, Wu J, et al. Slit2 inhibits glioma cell invasion in the brain by suppression of Cdc42 activity. Neuro Oncol. 2009;11:779-89 pubmed publisher
  • western blot; human; fig 4
Lapyckyj L, Castillo L, Matos M, Gabrielli N, Lüthy I, Vazquez Levin M. Expression analysis of epithelial cadherin and related proteins in IBH-6 and IBH-4 human breast cancer cell lines. J Cell Physiol. 2010;222:596-605 pubmed publisher
  • western blot; human; fig 1
Marín Briggiler C, Lapyckyj L, Gonzalez Echeverria M, Rawe V, Alvarez Sedó C, Vazquez Levin M. Neural cadherin is expressed in human gametes and participates in sperm-oocyte interaction events. Int J Androl. 2010;33:e228-39 pubmed publisher
  • western blot; mouse; fig 7
Hwang C, Song K, Kim C, Choi H, Guo X, Law P, et al. Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor. J Cell Mol Med. 2009;13:3591-615 pubmed publisher
  • western blot; human; fig 3
Li Z, Zhou Z, Welch D, Donahue H. Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs. Clin Exp Metastasis. 2008;25:893-901 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 3b
  • western blot; human; 1:250; fig 5b
Mosnier J, Kandel C, Cazals Hatem D, Bou Hanna C, Gournay J, Jarry A, et al. N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas. Mod Pathol. 2009;22:182-90 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Fondrevelle M, Kantelip B, Reiter R, Chopin D, Thiery J, Monnien F, et al. The expression of Twist has an impact on survival in human bladder cancer and is influenced by the smoking status. Urol Oncol. 2009;27:268-76 pubmed publisher
  • immunocytochemistry; mouse; fig 6
  • western blot; human; fig 3c
Agarwal S, Lee D, Kiener H, Brenner M. Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes. Arthritis Rheum. 2008;58:1044-54 pubmed publisher
  • immunohistochemistry; mouse; fig 3
Li J, Levin M, Xiong Y, Petrenko N, Patel V, Radice G. N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility. J Mol Cell Cardiol. 2008;44:597-606 pubmed publisher
  • immunocytochemistry; rat; fig 2
Lim S, Lim K, Giuliano R, Federoff H. Temporal and spatial localization of nectin-1 and l-afadin during synaptogenesis in hippocampal neurons. J Comp Neurol. 2008;507:1228-44 pubmed publisher
  • western blot; human; fig 6
Wu J, Yan H, Chen W, Chen W, Wang C, Chi Y, et al. JNK signaling pathway is required for bFGF-mediated surface cadherin downregulation on HUVEC. Exp Cell Res. 2008;314:421-9 pubmed publisher
  • western blot; human; fig 10
Braun A, Xu H, Hu F, Kocherlakota P, Siegel D, Chander P, et al. Paucity of pericytes in germinal matrix vasculature of premature infants. J Neurosci. 2007;27:12012-24 pubmed
  • western blot; rat; 0.1 ug/ml
Zhang S, Liu Y, Huang G, Liu L. Aconitine alters connexin43 phosphorylation status and [Ca2+] oscillation patterns in cultured ventricular myocytes of neonatal rats. Toxicol In Vitro. 2007;21:1476-85 pubmed
  • western blot; mouse
Hwang C, Song K, Kim C, Choi H, Guo X, Law P, et al. Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. Mol Cell Biol. 2007;27:4720-36 pubmed
  • immunohistochemistry - frozen section; rat; 1:50
Wang C, Mruk D, Lee W, Cheng C. Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface. Exp Cell Res. 2007;313:1373-92 pubmed
  • immunocytochemistry; mouse; 1:100; fig 2
Sharma M, Henderson B. IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli. J Biol Chem. 2007;282:8545-56 pubmed
  • western blot; mouse; 1:1000
Chang M, Boulden J, Sutanto Ward E, DuHadaway J, Soler A, Muller A, et al. Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression. Cancer Res. 2007;67:100-7 pubmed
  • immunohistochemistry; mouse
Blixt A, Landgren H, Johansson B, Carlsson P. Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage. Dev Biol. 2007;302:218-29 pubmed
  • immunohistochemistry; dogs; 1:25; fig 5
Moreno Bueno G, Cubillo E, Sarrio D, Peinado H, Rodriguez Pinilla S, Villa S, et al. Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition. Cancer Res. 2006;66:9543-56 pubmed
  • immunohistochemistry - paraffin section; human; 1:200
Lascombe I, Clairotte A, Fauconnet S, Bernardini S, Wallerand H, Kantelip B, et al. N-cadherin as a novel prognostic marker of progression in superficial urothelial tumors. Clin Cancer Res. 2006;12:2780-7 pubmed
  • western blot; human; fig 6
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  • immunohistochemistry - paraffin section; rat; tbl 1
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  • immunohistochemistry - paraffin section; mouse; 1:100; fig 2
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product information
Product Type :
Antibody
Product Name :
N-cadherin Monoclonal Antibody (3B9)
Catalog # :
33-3900
Quantity :
100 ug
Price :
US 496.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Chicken, Human, Mouse, Porcine, Rat
Applications :
Immunocytochemistry: 1-3 ug/mL, Immunohistochemistry (Paraffin): 1-5 ug/mL, Immunoprecipitation: 3-5 ug, Western Blot: 1:500-1:1,000
Species :
Chicken, Human, Mouse, Porcine, Rat
Clone :
3B9
Isotype :
IgG1, kappa
Storage :
-20 C
Description :
N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry.
Immunogen :
Recombinant domain corresponding to the intracellular domain of chicken N-Cadherin
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1-3 ug/mL, Immunohistochemistry (Paraffin): 1-5 ug/mL, Immunoprecipitation: 3-5 ug, Western Blot: 1:500-1:1,000
Aliases :
bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1 preproprotein; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; CDH2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; neural cadherin; Neural cadherin A; neural cadherin-2; neural calcium-dependent cell adhesion molecule; neural-cadherin; pac; Parachute; unnamed protein product; wu:fb47h04; XELAEV_18031953mg; ZNCAD
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA