p38 MAPK Monoclonal Antibody (p38-3F11) | Invitrogen 33-1300 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

p38 MAPK Monoclonal Antibody (p38-3F11)

catalog :

33-1300

quantity :

100 µg

price :

US 398.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

p38-3F11

reactivity :

human, mouse, rat, chimpanzee

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; rat; 1:250; loading ...; fig 5d western blot; rat; loading ...; fig 5a	Muraleva N, Stefanova N, Kolosova N. SkQ1 Suppresses the p38 MAPK Signaling Pathway Involved in Alzheimer's Disease-Like Pathology in OXYS Rats. Antioxidants (Basel). 2020;9: pubmed publisher
immunocytochemistry; rat; 1:500; fig 9 western blot; rat; fig s6	Lin S, Gou G, Hsia C, Ho C, Huang K, Wu Y, et al. Simulated Microgravity Disrupts Cytoskeleton Organization and Increases Apoptosis of Rat Neural Crest Stem Cells Via Upregulating CXCR4 Expression and RhoA-ROCK1-p38 MAPK-p53 Signaling. Stem Cells Dev. 2016;25:1172-93 pubmed publisher
western blot; mouse; fig 4	Nishiki Y, Adewola A, Hatanaka M, Templin A, Maier B, Mirmira R. Translational control of inducible nitric oxide synthase by p38 MAPK in islet β-cells. Mol Endocrinol. 2013;27:336-49 pubmed publisher
	Veazey J, Eliseeva S, Hillman S, Stiles K, Smyth T, Morrissey C, et al. Inhibiting Protein Kinase D Promotes Airway Epithelial Barrier Integrity in Mouse Models of Influenza A Virus Infection. Front Immunol. 2020;11:580401 pubmed publisher
	Le B, Podszywalow Bartnicka P, Maifrede S, Sullivan Reed K, Nieborowska Skorska M, Golovine K, et al. TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment. Cell Rep. 2020;33:108221 pubmed publisher
	Cook B, Rafiq R, Lee H, Banks K, El Debs M, Chiaravalli J, et al. Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β. Cell Chem Biol. 2019;: pubmed publisher
	Schulz R, Aker S, Belosjorow S, Konietzka I, Rauen U, Heusch G. Stress kinase phosphorylation is increased in pacing-induced heart failure in rabbits. Am J Physiol Heart Circ Physiol. 2003;285:H2084-90 pubmed
	Waetzig G, Seegert D, Rosenstiel P, Nikolaus S, Schreiber S. p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease. J Immunol. 2002;168:5342-51 pubmed

product information

Product Type :

Antibody

Product Name :

p38 MAPK Monoclonal Antibody (p38-3F11)

Catalog # :

33-1300

Quantity :

100 µg

Price :

US 398.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5-20 µg/mL, Western Blot: 1.0 µg/mL

Species :

Human, Mouse, Non-human primate, Rat

Clone :

p38-3F11

Isotype :

IgG2a, kappa

Storage :

-20°C

Description :

The p38 MAPK cascade regulates a variety of cellular responses to stress, inflammation, and other signals. p38 MAPK is relatively inactive in the nonphosphorylated form and becomes rapidly activated by dual phosphorylation of a Thr-Gly-Tyr motifs. There are four isoforms of p38 MAPK, which differ in their tissue expression and affinity for upstream activators and downstream effectors. When cells are exposed to tumor necrosis factor, interleukin-1, heat shock, or other activating stimuli, activation of MAPK kinase-3 occurs by phosphorylation. Activated MAPK kinase-3/6 phosphorylate each residue of Thr180 and Tyr182 in p38 MAPK. Phospho-p38 MAPK activates ATF-2, CHOP-1, MEF-2 and other transcription factors through phosphorylation.

Immunogen :

Full-length recombinant mouse p38 protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5-20 µg/mL, Western Blot: 1.0 µg/mL

Aliases :

Crk1; CSAID-binding protein; Csaids binding protein; CSBP; CSBP1; CSBP2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Exip; Hog; MAP kinase 11; MAP kinase 13; MAP kinase 14; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38 alpha; MAP kinase p38 beta; MAP kinase p38 delta; MAPK 11; MAPK 13; MAPK 14; Mapk11; Mapk13; MAPK-13; Mapk14; MAX-interacting protein 2; mitogen activated protein kinase 11; mitogen activated protein kinase 13; mitogen activated protein kinase 14; mitogen-activated protein kinase 11; Mitogen-activated protein kinase 13; mitogen-activated protein kinase 14; mitogen-activated protein kinase 14A; mitogen-activated protein kinase p38 alpha; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38 delta; mitogen-activated protein kinase p38-2; MXI2; p38; p38 alpha; p38 delta MAP kinase; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38-2; p38a; p38ALPHA; p38-alpha; p38alpha Exip; P38b; p38Beta; p38beta2; p38delta; p38Hog; p38MAPK; Prkm11; PRKM13; PRKM14; Prkm15; protein kinase, mitogen activated kinase, 11, p38beta; reactive kinase; RK; SAPK/Erk/kinase 4; SAPK2; SAPK2A; SAPK2B; SAPK4; Serk4; Stress-activated protein kinase 2a; Stress-activated protein kinase 2b; Stress-activated protein kinase 4; stress-activated protein kinase-2; stress-activated protein kinase-2b; tRNA synthetase cofactor p38

more info or order :

Invitrogen product webpage