PKP1 Monoclonal Antibody (10B2) | Invitrogen 32-5700 product information

product summary

company name :

Invitrogen

other brands :

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product type :

antibody

product name :

PKP1 Monoclonal Antibody (10B2)

catalog :

32-5700

quantity :

100 µg

price :

US 458.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10B2

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human; loading ...; fig 2e	Sprecher E, Molho Pessach V, Ingber A, Sagi E, Indelman M, Bergman R. Homozygous splice site mutations in PKP1 result in loss of epidermal plakophilin 1 expression and underlie ectodermal dysplasia/skin fragility syndrome in two consanguineous families. J Invest Dermatol. 2004;122:647-51 pubmed
	Bonne S, Gilbert B, Hatzfeld M, Chen X, Green K, van Roy F. Defining desmosomal plakophilin-3 interactions. J Cell Biol. 2003;161:403-16 pubmed
	Kljuic A, Bazzi H, Sundberg J, Martinez Mir A, O Shaughnessy R, Mahoney M, et al. Desmoglein 4 in hair follicle differentiation and epidermal adhesion: evidence from inherited hypotrichosis and acquired pemphigus vulgaris. Cell. 2003;113:249-60 pubmed

product information

Product Type :

Antibody

Product Name :

PKP1 Monoclonal Antibody (10B2)

Catalog # :

32-5700

Quantity :

100 µg

Price :

US 458.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 2 µg/mL, Immunoprecipitation: 2 µg, Western Blot: 1-3 µg/mL

Species :

Human

Clone :

10B2

Isotype :

IgG1

Storage :

-20°C

Description :

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

Immunogen :

N-terminus of Human plakophilin-1.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Immunoprecipitation: 2 µg, Western Blot: 1-3 µg/mL

Aliases :

AI528551; armadillo; B6P; band 6; band 6 polypeptide B6P; band 6 protein; Band-6 protein; MGC138829; Pkp1; plakophilin; plakophilin 1; plakophilin 1 (ectodermal dysplasia/skin fragility syndrome); plakophilin-1

more info or order :

Invitrogen product webpage