U2AF2 Monoclonal Antibody (222-6) | Invitrogen 32-4700 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

U2AF2 Monoclonal Antibody (222-6)

catalog :

32-4700

quantity :

100µg

price :

US 341

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

222-6

reactivity :

human

application :

western blot

citations: 2

Reference
Bracken C, Wall S, Barré B, Panov K, Ajuh P, Perkins N. Regulation of cyclin D1 RNA stability by SNIP1. Cancer Res. 2008;68:7621-8 pubmed publisher
Glanzer J, Miyashiro K, Sul J, Barrett L, Belt B, Haydon P, et al. RNA splicing capability of live neuronal dendrites. Proc Natl Acad Sci U S A. 2005;102:16859-64 pubmed

product information

Product Type :

Antibody

Product Name :

U2AF2 Monoclonal Antibody (222-6)

Catalog # :

32-4700

Quantity :

100µg

Price :

US 341

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Western Blot: 1-3 µg/mL

Species :

Human

Clone :

222-6

Isotype :

IgG2a

Storage :

-20°C

Description :

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.

Immunogen :

An amino acid peptide derived from human U2AF65.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1-3 µg/mL

Aliases :

U2AF65, U2 (RNU2) small nuclear RNA auxiliary factor 2, U2 auxiliary factor 65 kDa subunit, U2 small nuclear ribonucleoprotein auxiliary factor (65kD), U2 snRNP auxiliary factor large subunit, hU2AF(65), hU2AF65, splicing factor U2AF 65 kD subunit, splicing factor U2AF