SRSF1 Monoclonal Antibody (103) | Invitrogen 32-4600 product information

product summary

company name :

Invitrogen

other brands :

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product type :

antibody

product name :

SRSF1 Monoclonal Antibody (103)

catalog :

32-4600

quantity :

100 µg

price :

US 430.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

103

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 29

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:100; loading ...; fig s1c	Goenka A, Sengupta S, Pandey R, Parihar R, Mohanta G, Mukerji M, et al. Human satellite-III non-coding RNAs modulate heat-shock-induced transcriptional repression. J Cell Sci. 2016;129:3541-3552 pubmed
immunohistochemistry - paraffin section; human; 1:1000; fig 1 western blot; human; 1:1000; fig 1	Park W, Kim H, Kang D, Ryu J, Choi K, Lee G, et al. Comparative expression patterns and diagnostic efficacies of SR splicing factors and HNRNPA1 in gastric and colorectal cancer. BMC Cancer. 2016;16:358 pubmed publisher
immunohistochemistry; human; fig 1	Ishida K, Miyauchi K, Kimura Y, Mito M, Okada S, Suzuki T, et al. Regulation of gene expression via retrotransposon insertions and the noncoding RNA 4.5S RNAH. Genes Cells. 2015;20:887-901 pubmed publisher
western blot; human; loading ...; fig 5i	Comiskey D, Jacob A, Singh R, Tapia Santos A, Chandler D. Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage. Nucleic Acids Res. 2015;43:4202-18 pubmed publisher
immunocytochemistry; human	Du C, Ma X, Meruvu S, Hugendubler L, Mueller E. The adipogenic transcriptional cofactor ZNF638 interacts with splicing regulators and influences alternative splicing. J Lipid Res. 2014;55:1886-96 pubmed publisher
western blot; human	Jacob A, Singh R, Mohammad F, Bebee T, Chandler D. The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA. J Biol Chem. 2014;289:17350-64 pubmed publisher
immunocytochemistry; human western blot; human	Rappe U, Schlechter T, Aschoff M, Hotz Wagenblatt A, Hofmann I. Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing. J Biol Chem. 2014;289:12421-34 pubmed publisher
immunocytochemistry; human; fig s8	Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang L, et al. A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem Biol. 2014;10:93-5 pubmed publisher
immunocytochemistry; human	Gu B, Eick D, Bensaude O. CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo. Nucleic Acids Res. 2013;41:1591-603 pubmed publisher
western blot; mouse	Nakagawa S, Ip J, Shioi G, Tripathi V, Zong X, Hirose T, et al. Malat1 is not an essential component of nuclear speckles in mice. RNA. 2012;18:1487-99 pubmed publisher
immunocytochemistry; human; 1:500; fig s2 western blot; human; 1:500; fig 6	Waks Z, Klein A, Silver P. Cell-to-cell variability of alternative RNA splicing. Mol Syst Biol. 2011;7:506 pubmed publisher
immunocytochemistry; mouse; fig 1	Hepperger C, Mannes A, Merz J, Peters J, Dietzel S. Three-dimensional positioning of genes in mouse cell nuclei. Chromosoma. 2008;117:535-51 pubmed publisher
immunocytochemistry; human; 1:30; fig 6	Inoue A, Tsugawa K, Tokunaga K, Takahashi K, Uni S, Kimura M, et al. S1-1 nuclear domains: characterization and dynamics as a function of transcriptional activity. Biol Cell. 2008;100:523-35 pubmed publisher
	Gao S, Esparza M, Dehghan I, Aksenova V, Zhang K, Batten K, et al. Nuclear speckle integrity and function require TAO2 kinase. Proc Natl Acad Sci U S A. 2022;119:e2206046119 pubmed publisher
	Hall A, Pohl S, Cammareri P, Aitken S, Younger N, Raponi M, et al. RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer. Nat Commun. 2022;13:2791 pubmed publisher
	Kao C, Nie Y, Ren S, De Costa N, Pandey R, Hong J, et al. Mechanism of action of hepatitis B virus S antigen transport-inhibiting oligonucleotide polymer, STOPS, molecules. Mol Ther Nucleic Acids. 2022;27:335-348 pubmed publisher
	Lam F, Kong Y, Huang Q, Vu Han T, Maffa A, Kasper E, et al. BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision events and DNA damage. Nat Commun. 2020;11:4083 pubmed publisher
	Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa M, Uriarte I, et al. Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins. Nucleic Acids Res. 2019;47:3450-3466 pubmed publisher
	Vendramin R, Verheyden Y, Ishikawa H, Goedert L, Nicolas E, Saraf K, et al. SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation. Nat Struct Mol Biol. 2018;25:1035-1046 pubmed publisher
	Yang X, Yang Y, Sun B, Chen Y, Xu J, Lai W, et al. 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C reader. Cell Res. 2017;27:606-625 pubmed publisher
	Mulay A, Akram K, Williams D, Armes H, Russell C, Hood D, et al. An in vitro model of murine middle ear epithelium. Dis Model Mech. 2016;9:1405-1417 pubmed
	Lee M, Dworkin A, Gildea D, Trivedi N, Moorhead G, Crawford N. RRP1B is a metastasis modifier that regulates the expression of alternative mRNA isoforms through interactions with SRSF1. Oncogene. 2014;33:1818-27 pubmed publisher
	Zheng G, Dahl J, Niu Y, Fedorcsak P, Huang C, Li C, et al. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol Cell. 2013;49:18-29 pubmed publisher
	Bebee T, Dominguez C, Samadzadeh Tarighat S, Akehurst K, Chandler D. Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model. Hum Mol Genet. 2012;21:4301-13 pubmed publisher
	Aksaas A, Eikvar S, Akusjarvi G, Skålhegg B, Kvissel A. Protein kinase a-dependent phosphorylation of serine 119 in the proto-oncogenic serine/arginine-rich splicing factor 1 modulates its activity as a splicing enhancer protein. Genes Cancer. 2011;2:841-51 pubmed publisher
	Iijima T, Wu K, Witte H, Hanno Iijima Y, Glatter T, Richard S, et al. SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1. Cell. 2011;147:1601-14 pubmed publisher
	Benmoyal Segal L, Soreq L, Ben Shaul Y, Ben Ari S, Ben Moshe T, Aviel S, et al. Adaptive alternative splicing correlates with less environmental risk of parkinsonism. Neurodegener Dis. 2012;9:87-98 pubmed publisher
	Tyson Capper A, Bailey J, Krainer A, Robson S, Europe Finner G. The switch in alternative splicing of cyclic AMP-response element modulator protein CREM{tau}2{alpha} (activator) to CREM{alpha} (repressor) in human myometrial cells is mediated by SRp40. J Biol Chem. 2005;280:34521-9 pubmed
	Andrin C, Hendzel M. F-actin-dependent insolubility of chromatin-modifying components. J Biol Chem. 2004;279:25017-23 pubmed

product information

Product Type :

Antibody

Product Name :

SRSF1 Monoclonal Antibody (103)

Catalog # :

32-4600

Quantity :

100 µg

Price :

US 430.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 2 µg/mL, Western Blot: 2 µg/mL

Species :

Human, Mouse, Rat

Clone :

103

Isotype :

IgG1

Storage :

-20°C

Description :

UBE2E2 catalyzes the covalent attachment of ubiquitin to other proteins.

Immunogen :

Recombinant SF2/ASF protein.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Western Blot: 2 µg/mL

Aliases :

1110054N12Rik; 5730507C05Rik; 6330415C05Rik; AI482334; Alternative-splicing factor 1; ASF; ASF/SF2; ASF-1; AW491331; OK/SW-cl.3; pre-mRNA-splicing factor SF2, P33 subunit; pre-mRNA-splicing factor SRp30a; serine and arginine rich splicing factor 1; serine/arginine-rich splicing factor 1; SF2; SF2p33; SFRS1; splicing factor 2; splicing factor, arginine/serine-rich 1; splicing factor, arginine/serine-rich 1 (ASF/SF2); splicing factor, arginine/serine-rich 1B; splicing factor, arginine/serine-rich, 30-KD, A; SR splicing factor 1; SRp30a; Srsf1

more info or order :

Invitrogen product webpage