| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:2000; loading ...; fig 3d
| Sajini A, Choudhury N, Wagner R, Bornelöv S, Selmi T, Spanos C, et al. Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation. Nat Commun. 2019;10:2550 pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- reverse phase protein lysate microarray; human; loading ...; fig 7a
| Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher |
- reverse phase protein lysate microarray; human; loading ...; fig 3a
| . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher |
- western blot; human; loading ...; fig 6a
| Brillen A, Schöneweis K, Walotka L, Hartmann L, Muller L, Ptok J, et al. Succession of splicing regulatory elements determines cryptic 5΄ss functionality. Nucleic Acids Res. 2017;45:4202-4216 pubmed publisher |
- western blot; human; loading ...; fig 9b
| Ajiro M, Tang S, Doorbar J, Zheng Z. Serine/Arginine-Rich Splicing Factor 3 and Heterogeneous Nuclear Ribonucleoprotein A1 Regulate Alternative RNA Splicing and Gene Expression of Human Papillomavirus 18 through Two Functionally Distinguishable cis Elements. J Virol. 2016;90:9138-52 pubmed publisher |
- western blot; mouse; fig 7
| Llorian M, Gooding C, Bellora N, Hallegger M, Buckroyd A, Wang X, et al. The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators. Nucleic Acids Res. 2016;44:8933-8950 pubmed |
- western blot; rat; 1:1000; tbl 1
| Miletta M, Petkovic V, Eblé A, Flück C, Mullis P. Rescue of Isolated GH Deficiency Type II (IGHD II) via Pharmacologic Modulation of GH-1 Splicing. Endocrinology. 2016;157:3972-3982 pubmed |
- western blot; human; 1:1000; fig 2
| Klymenko T, Hernández López H, MacDonald A, Bodily J, Graham S. Human Papillomavirus E2 Regulates SRSF3 (SRp20) To Promote Capsid Protein Expression in Infected Differentiated Keratinocytes. J Virol. 2016;90:5047-58 pubmed publisher |
- immunohistochemistry; human; fig s5
- western blot; human; fig 7
- western blot; mouse; fig 7
| Ajiro M, Jia R, Yang Y, Zhu J, Zheng Z. A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells. Nucleic Acids Res. 2016;44:1854-70 pubmed publisher |
| Rahman M, Azuma Y, Nasrin F, Takeda J, Nazim M, Bin Ahsan K, et al. SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndrome. Sci Rep. 2015;5:13208 pubmed publisher |
| Palhais B, Præstegaard V, Sabaratnam R, Doktor T, Lutz S, Burda P, et al. Splice-shifting oligonucleotide (SSO) mediated blocking of an exonic splicing enhancer (ESE) created by the prevalent c.903+469T>C MTRR mutation corrects splicing and restores enzyme activity in patient cells. Nucleic Acids Res. 2015;43:4627-39 pubmed publisher |
- western blot; human; 1:1000
| McFarlane M, MacDonald A, Stevenson A, Graham S. Human Papillomavirus 16 Oncoprotein Expression Is Controlled by the Cellular Splicing Factor SRSF2 (SC35). J Virol. 2015;89:5276-87 pubmed publisher |
- immunoprecipitation; human
| Salton M, Voss T, Misteli T. Identification by high-throughput imaging of the histone methyltransferase EHMT2 as an epigenetic regulator of VEGFA alternative splicing. Nucleic Acids Res. 2014;42:13662-73 pubmed publisher |
- chromatin immunoprecipitation; human
| Chang S, Chang W, Lu C, Tarn W. Alanine repeats influence protein localization in splicing speckles and paraspeckles. Nucleic Acids Res. 2014;42:13788-98 pubmed publisher |
- western blot; human; fig 4
| Majerciak V, Lu M, Li X, Zheng Z. Attenuation of the suppressive activity of cellular splicing factor SRSF3 by Kaposi sarcoma-associated herpesvirus ORF57 protein is required for RNA splicing. RNA. 2014;20:1747-58 pubmed publisher |
- immunoprecipitation; human; fig 8
- western blot; human; fig 8
| Mui M, Kucharski M, Miron M, Hur W, Berghuis A, Blanchette P, et al. Identification of the adenovirus E4orf4 protein binding site on the B55? and Cdc55 regulatory subunits of PP2A: Implications for PP2A function, tumor cell killing and viral replication. PLoS Pathog. 2013;9:e1003742 pubmed publisher |
| Li X, Johansson C, Cardoso Palacios C, Mossberg A, Dhanjal S, Bergvall M, et al. Eight nucleotide substitutions inhibit splicing to HPV-16 3'-splice site SA3358 and reduce the efficiency by which HPV-16 increases the life span of primary human keratinocytes. PLoS ONE. 2013;8:e72776 pubmed publisher |
- western blot; human; fig 3
| Bruun G, Doktor T, Andresen B. A synonymous polymorphic variation in ACADM exon 11 affects splicing efficiency and may affect fatty acid oxidation. Mol Genet Metab. 2013;110:122-8 pubmed publisher |
- western blot; human; fig 1
| Vivarelli S, Lenzken S, Ruepp M, Ranzini F, Maffioletti A, Alvarez R, et al. Paraquat modulates alternative pre-mRNA splicing by modifying the intracellular distribution of SRPK2. PLoS ONE. 2013;8:e61980 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:1000
| Gout S, Brambilla E, Boudria A, Drissi R, Lantuejoul S, Gazzeri S, et al. Abnormal expression of the pre-mRNA splicing regulators SRSF1, SRSF2, SRPK1 and SRPK2 in non small cell lung carcinoma. PLoS ONE. 2012;7:e46539 pubmed publisher |
- western blot; human; fig 4
| Becker K, Braune M, Benderska N, Buratti E, Baralle F, Villmann C, et al. A retroelement modifies pre-mRNA splicing: the murine Glrb(spa) allele is a splicing signal polymorphism amplified by long interspersed nuclear element insertion. J Biol Chem. 2012;287:31185-94 pubmed publisher |
- chromatin immunoprecipitation; mouse; 4 ug; fig 3
- western blot; mouse; 1:2000; fig 3
| Pradeepa M, Sutherland H, Ule J, Grimes G, Bickmore W. Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing. PLoS Genet. 2012;8:e1002717 pubmed publisher |
- western blot; human; fig 2
| Markus M, Marques F, Morris B. Resveratrol, by modulating RNA processing factor levels, can influence the alternative splicing of pre-mRNAs. PLoS ONE. 2011;6:e28926 pubmed publisher |
- western blot; human; 1:500; fig 4
| Piekielko Witkowska A, Wiszomirska H, Wojcicka A, Poplawski P, Boguslawska J, Tanski Z, et al. Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors. PLoS ONE. 2010;5:e13690 pubmed publisher |
- chromatin immunoprecipitation; human; fig 8
| He M, Shah D, Choung H, Coffman F. The splicing factor SF2/ASF binds to ARS homologs in a human rDNA replication origin. Cell Cycle. 2009;8:2631-42 pubmed |
- western blot; human; 1:250; fig 2
| Adair R, Liebisch G, Su Y, COLBERG POLEY A. Alteration of cellular RNA splicing and polyadenylation machineries during productive human cytomegalovirus infection. J Gen Virol. 2004;85:3541-53 pubmed |
| Farshadyeganeh P, Nazim M, Zhang R, Ohkawara B, Nakajima K, Rahman M, et al. Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction. iScience. 2023;26:107746 pubmed publisher |
| MacDonald K, Nicholson Puthenveedu S, Tageldein M, Khasnis S, Arrowsmith C, Harding S. Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei. Nat Commun. 2023;14:556 pubmed publisher |
| Aktaş Samur A, Fulciniti M, Avet Loiseau H, Lopez M, Derebail S, Corre J, et al. In-depth analysis of alternative splicing landscape in multiple myeloma and potential role of dysregulated splicing factors. Blood Cancer J. 2022;12:171 pubmed publisher |
| Sertznig H, Roesmann F, Wilhelm A, Heininger D, Bleekmann B, Elsner C, et al. SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps. Front Immunol. 2022;13:935800 pubmed publisher |
| Del Giudice M, Foster J, Peirone S, Rissone A, Caizzi L, Gaudino F, et al. FOXA1 regulates alternative splicing in prostate cancer. Cell Rep. 2022;40:111404 pubmed publisher |
| Mart xed nez Pizarro A, Leal F, Holm L, Doktor T, Petersen U, Bueno M, et al. Antisense Oligonucleotide Rescue of Deep-Intronic Variants Activating Pseudoexons in the 6-Pyruvoyl-Tetrahydropterin Synthase Gene. Nucleic Acid Ther. 2022;32:378-390 pubmed publisher |
| Baymiller M, Nordick B, Forsyth C, Martinis S. Tissue-specific alternative splicing separates the catalytic and cell signaling functions of human leucyl-tRNA synthetase. J Biol Chem. 2022;298:101757 pubmed publisher |
| Dahal S, Cheng R, Cheung P, Been T, Malty R, Geng M, et al. The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation. Viruses. 2021;14: pubmed publisher |
| Jia T, Jacquet T, Dalonneau F, Coudert P, Vaganay E, Exbrayat Héritier C, et al. FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells. BMC Biol. 2021;19:173 pubmed publisher |
| Zhou D, Couture S, Scott M, Abou Elela S. RBFOX2 alters splicing outcome in distinct binding modes with multiple protein partners. Nucleic Acids Res. 2021;49:8370-8383 pubmed publisher |
| Zhou D, Zhu X, Wu X, Zheng J, Tou L, Zhou Y. The effect of splicing MST1R in gastric cancer was enhanced by lncRNA FENDRR. Exp Ther Med. 2021;22:798 pubmed publisher |
| Liang G, Chen S, Xin S, Dong L. Overexpression of hsa_circ_0001445 reverses oxLDL‑induced inhibition of HUVEC proliferation via SRSF1. Mol Med Rep. 2021;24: pubmed publisher |
| Olthof A, White A, Mieruszynski S, Doggett K, Lee M, Chakroun A, et al. Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns. Nucleic Acids Res. 2021;49:3524-3545 pubmed publisher |
| Katsuyama T, Li H, Krishfield S, Kyttaris V, Moulton V. Splicing factor SRSF1 limits IFN-γ production via RhoH and ameliorates experimental nephritis. Rheumatology (Oxford). 2021;60:420-429 pubmed publisher |
| Miro J, Bouge A, Murauer E, Beyne E, Da Cunha D, Claustres M, et al. First Identification of RNA-Binding Proteins That Regulate Alternative Exons in the Dystrophin Gene. Int J Mol Sci. 2020;21: pubmed publisher |
| Vaklavas C, Blume S, Grizzle W. Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer. Transl Oncol. 2020;13:452-470 pubmed publisher |
| Peng W, Liu J, Li C, Ma R, Jie J. hnRNPK promotes gastric tumorigenesis through regulating CD44E alternative splicing. Cancer Cell Int. 2019;19:335 pubmed publisher |
| Huang J, Chang S, Lu Y, Wang J, Si Y, Zhang L, et al. Enhanced osteopontin splicing regulated by RUNX2 is HDAC-dependent and induces invasive phenotypes in NSCLC cells. Cancer Cell Int. 2019;19:306 pubmed publisher |
| Fu K, Tian S, Tan H, Wang C, Wang H, Wang M, et al. Biological and RNA regulatory function of MOV10 in mammalian germ cells. BMC Biol. 2019;17:39 pubmed publisher |
| Girstun A, Ishikawa T, Staron K. Effects of SRSF1 on subnuclear localization of topoisomerase I. J Cell Biochem. 2019;: pubmed publisher |
| Zagore L, Sweet T, Hannigan M, Weyn Vanhentenryck S, Jobava R, Hatzoglou M, et al. DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions. Cell Rep. 2018;25:1225-1240.e6 pubmed publisher |
| Martínez Pizarro A, Dembic M, Perez B, Andresen B, Desviat L. Intronic PAH gene mutations cause a splicing defect by a novel mechanism involving U1snRNP binding downstream of the 5' splice site. PLoS Genet. 2018;14:e1007360 pubmed publisher |
| Ahsan K, Masuda A, Rahman M, Takeda J, Nazim M, Ohkawara B, et al. SRSF1 suppresses selection of intron-distal 5' splice site of DOK7 intron 4 to generate functional full-length Dok-7 protein. Sci Rep. 2017;7:10446 pubmed publisher |
| Xie N, Chen M, Dai R, Zhang Y, Zhao H, Song Z, et al. SRSF1 promotes vascular smooth muscle cell proliferation through a Δ133p53/EGR1/KLF5 pathway. Nat Commun. 2017;8:16016 pubmed publisher |
| Doktor T, Schrøder L, Andersen H, Brøner S, Kitewska A, Sørensen C, et al. Absence of an intron splicing silencer in porcine Smn1 intron 7 confers immunity to the exon skipping mutation in human SMN2. PLoS ONE. 2014;9:e98841 pubmed publisher |
| Bonomi S, di Matteo A, Buratti E, Cabianca D, Baralle F, Ghigna C, et al. HnRNP A1 controls a splicing regulatory circuit promoting mesenchymal-to-epithelial transition. Nucleic Acids Res. 2013;41:8665-79 pubmed publisher |
| Ji X, Zhou Y, Pandit S, Huang J, Li H, Lin C, et al. SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase. Cell. 2013;153:855-68 pubmed publisher |
| Aksaas A, Eikvar S, Akusjarvi G, Skålhegg B, Kvissel A. Protein kinase a-dependent phosphorylation of serine 119 in the proto-oncogenic serine/arginine-rich splicing factor 1 modulates its activity as a splicing enhancer protein. Genes Cancer. 2011;2:841-51 pubmed publisher |
| Lopez Mejia I, Vautrot V, de Toledo M, Behm Ansmant I, Bourgeois C, Navarro C, et al. A conserved splicing mechanism of the LMNA gene controls premature aging. Hum Mol Genet. 2011;20:4540-55 pubmed publisher |
| Rosner M, Hengstschlager M. Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR. Oncogene. 2011;30:4509-22 pubmed publisher |
| Huang S, Cho A, Norton S, Liu E, Park J, Zhou A, et al. Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene. Blood. 2009;114:4233-42 pubmed publisher |
| Baldin V, Militello M, Thomas Y, Doucet C, Fic W, Boireau S, et al. A novel role for PA28gamma-proteasome in nuclear speckle organization and SR protein trafficking. Mol Biol Cell. 2008;19:1706-16 pubmed publisher |
| Glanzer J, Miyashiro K, Sul J, Barrett L, Belt B, Haydon P, et al. RNA splicing capability of live neuronal dendrites. Proc Natl Acad Sci U S A. 2005;102:16859-64 pubmed |
| Buratti E, Muro A, Giombi M, Gherbassi D, Iaconcig A, Baralle F. RNA folding affects the recruitment of SR proteins by mouse and human polypurinic enhancer elements in the fibronectin EDA exon. Mol Cell Biol. 2004;24:1387-400 pubmed |
| Rooke N, Markovtsov V, Cagavi E, Black D. Roles for SR proteins and hnRNP A1 in the regulation of c-src exon N1. Mol Cell Biol. 2003;23:1874-84 pubmed |
