SKP1 Monoclonal Antibody (1C10F4) | Invitrogen 32-3800 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SKP1 Monoclonal Antibody (1C10F4)

catalog :

32-3800

quantity :

100 ug

price :

US 451.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1C10F4

reactivity :

human

application :

western blot, ELISA, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:500	Honarpour N, Rose C, Brumbaugh J, Anderson J, Graham R, Sweredoski M, et al. F-box protein FBXL16 binds PP2A-B55? and regulates differentiation of embryonic stem cells along the FLK1+ lineage. Mol Cell Proteomics. 2014;13:780-91 pubmed publisher
western blot; human	Chen Q, Xie W, Kuhn D, Voorhees P, Lopez Girona A, Mendy D, et al. Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy. Blood. 2008;111:4690-9 pubmed publisher
western blot; human; fig 1	Donzelli M, Busino L, Chiesa M, Ganoth D, Hershko A, Draetta G. Hierarchical order of phosphorylation events commits Cdc25A to betaTrCP-dependent degradation. Cell Cycle. 2004;3:469-71 pubmed
western blot; human; fig 4	Busino L, Donzelli M, Chiesa M, Guardavaccaro D, Ganoth D, Dorrello N, et al. Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage. Nature. 2003;426:87-91 pubmed
	Tsai M, Lee C, Huang L, Chen Y, Liu W, Lin C, et al. CRISPR-mediated knockout of VEGFR2/KDR inhibits cell growth in a squamous thyroid cancer cell line. FEBS Open Bio. 2022;12:993-1005 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SKP1 Monoclonal Antibody (1C10F4)

Catalog # :

32-3800

Quantity :

100 ug

Price :

US 451.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 0.1-1.0 ug/mL, Immunoprecipitation: 5-10 ug/mL, Western Blot: 1-3 ug/mL

Species :

Human

Clone :

1C10F4

Isotype :

IgG1

Storage :

-20 C

Description :

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteasome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Immunogen :

Recombinant human SKP1 (p19) protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.1-1.0 ug/mL, Immunoprecipitation: 5-10 ug/mL, Western Blot: 1-3 ug/mL

Aliases :

15kDa; 2610043E24Rik; 2610206H23Rik; cyclin A/CDK2-associated p19; cyclin A/CDK2-associated protein p19; cyclin-A/CDK2-associated protein p19; EMC19; MGC34403; OCP2; OCP-2; OCP-II; OCP-II protein; organ of Corti protein 2; Organ of Corti protein II; p19A; p19Skp1; polypeptide 1-like; RNA polymerase II elongation factor-like protein; RNA polymerase II elongation factor-like protein OCP2; SIII; Skp1; Skp1a; S-phase kinase-associated protein 1; S-phase kinase-associated protein 1A; TCEB1L; transcription elongation factor B polypeptide 1-like

more info or order :

Invitrogen product webpage