DRD3 Monoclonal Antibody (3A8) | Invitrogen 32-0900 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DRD3 Monoclonal Antibody (3A8)

catalog :

32-0900

quantity :

100µg

price :

US 345.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3A8

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; rat; 1:200	Chen Y, Hong F, Chen H, Fan R, Zhang X, Zhang Y, et al. Distinctive expression and cellular distribution of dopamine receptors in the pancreatic islets of rats. Cell Tissue Res. 2014;357:597-606 pubmed publisher
immunocytochemistry; rat; 1:600; fig 2A western blot; rat; 1:250; fig 3	Zeng C, Wang Z, Li H, Yu P, Zheng S, Wu L, et al. D3 dopamine receptor directly interacts with D1 dopamine receptor in immortalized renal proximal tubule cells. Hypertension. 2006;47:573-9 pubmed
	Nimchinsky E, Hof P, Janssen W, Morrison J, Schmauss C. Expression of dopamine D3 receptor dimers and tetramers in brain and in transfected cells. J Biol Chem. 1997;272:29229-37 pubmed

product information

Product Type :

Antibody

Product Name :

DRD3 Monoclonal Antibody (3A8)

Catalog # :

32-0900

Quantity :

100µg

Price :

US 345.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Non-human primate, Rat

Applications :

ELISA: 0.1-1.0 µg/mL, Immunohistochemistry: 1-5 µg/mL, Immunoprecipitation: 2-5 µg, Western Blot: 1-2 µg/mL

Species :

Human, Non-human primate, Rat

Clone :

3A8

Isotype :

IgG3

Storage :

-20°C

Description :

This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Immunogen :

Fusion protein incorporating amino acid residues 252-284 of the putative third cytoplasmic loop of the human D3 receptor.

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.1-1.0 µg/mL, Immunohistochemistry: 1-5 µg/mL, Immunoprecipitation: 2-5 µg, Western Blot: 1-2 µg/mL

Aliases :

D(3) dopamine receptor; D3 receptor; D3DR; D3nf; D3R; Dopamine 3 receptor; Dopamine D3 receptor; dopamine receptor 3; dopamine receptor D3; dopaminergic receptor D3; DRD3; essential tremor 1; ETM1; FET1