This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Mouse CD40 Ligand (TNFSF5) (soluble) Recombinant Protein, PeproTech
catalog :
315-15-250UG
quantity :
250 ug
price :
US 1218.00
citations: 31
Reference
Shinoda K, Zong D, Callen E, Wu W, Dumitrache L, Belinky F, et al. The dystonia gene THAP1 controls DNA double-strand break repair choice. Mol Cell. 2021;81:2611-2624.e10 pubmed publisher
Chen M, Zhao Z, Meng Q, Liang P, Su Z, Wu Y, et al. TRIM14 Promotes Noncanonical NF-κB Activation by Modulating p100/p52 Stability via Selective Autophagy. Adv Sci (Weinh). 2020;7:1901261 pubmed publisher
Andreani V, Ramamoorthy S, Pandey A, Lupar E, Nutt S, Lämmermann T, et al. Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function. Proc Natl Acad Sci U S A. 2018;115:E9630-E9639 pubmed publisher
Chen J, Cai Z, Bai M, Yu X, Zhang C, Cao C, et al. The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes. Cell Res. 2018;28:981-995 pubmed publisher
Gupta R, Somyajit K, Narita T, Maskey E, Stanlie A, Kremer M, et al. DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity. Cell. 2018;173:972-988.e23 pubmed publisher
Yu J, Choi S, Kim H, Lee N, Yun H, Kim S, et al. Generation of an osteoblast-based artificial niche that supports in vitro B lymphopoiesis. Exp Mol Med. 2017;49:e400 pubmed publisher
Ali R, Wuescher L, Dona K, Worth R. Platelets Mediate Host Defense against Staphylococcus aureus through Direct Bactericidal Activity and by Enhancing Macrophage Activities. J Immunol. 2017;198:344-351 pubmed
Basu S, Kaw S, D Souza L, Vaidya T, Bal V, Rath S, et al. Constitutive CD40 Signaling Calibrates Differentiation Outcomes in Responding B Cells via Multiple Molecular Pathways. J Immunol. 2016;197:761-70 pubmed publisher
Li Q, Harden J, Anderson C, Egilmez N. Tolerogenic Phenotype of IFN-?-Induced IDO+ Dendritic Cells Is Maintained via an Autocrine IDO-Kynurenine/AhR-IDO Loop. J Immunol. 2016;197:962-70 pubmed publisher
Wu H, Lo Y, Chan A, Law K, Mok M. Rel B-modified dendritic cells possess tolerogenic phenotype and functions on lupus splenic lymphocytes in vitro. Immunology. 2016;149:48-61 pubmed publisher
Pontejo S, Alejo A, Alcami A. Comparative Biochemical and Functional Analysis of Viral and Human Secreted Tumor Necrosis Factor (TNF) Decoy Receptors. J Biol Chem. 2015;290:15973-84 pubmed publisher
Carmi Y, Spitzer M, Linde I, Burt B, Prestwood T, Perlman N, et al. Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity. Nature. 2015;521:99-104 pubmed publisher
Clatworthy M, Harford S, Mathews R, Smith K. FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis. Proc Natl Acad Sci U S A. 2014;111:17971-6 pubmed publisher
Sun L, Li H, Luo H, Zhang L, Hu X, Yang T, et al. Phosphatase Wip1 is essential for the maturation and homeostasis of medullary thymic epithelial cells in mice. J Immunol. 2013;191:3210-20 pubmed publisher
Mok Y, Schwierzeck V, Thomas D, Vigorito E, Rayner T, Jarvis L, et al. MiR-210 is induced by Oct-2, regulates B cells, and inhibits autoantibody production. J Immunol. 2013;191:3037-3048 pubmed publisher
Pei H, Wu X, Liu T, Yu K, Jelinek D, Lou Z. The histone methyltransferase MMSET regulates class switch recombination. J Immunol. 2013;190:756-63 pubmed publisher
Yang D, Postnikov Y, Li Y, Tewary P, de la Rosa G, Wei F, et al. High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses. J Exp Med. 2012;209:157-71 pubmed publisher
Narayanan P, Lapteva N, Seethammagari M, Levitt J, Slawin K, Spencer D. A composite MyD88/CD40 switch synergistically activates mouse and human dendritic cells for enhanced antitumor efficacy. J Clin Invest. 2011;121:1524-34 pubmed publisher
Puebla Osorio N, Miyahara Y, Coimbatore S, Limon Flores A, Kazimi N, Ullrich S, et al. Induction of B-cell lymphoma by UVB radiation in p53 haploinsufficient mice. BMC Cancer. 2011;11:36 pubmed publisher
Su Y, Hao Z, Hirao A, Yamamoto K, Lin W, Young A, et al. 14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1. Proc Natl Acad Sci U S A. 2011;108:1555-60 pubmed publisher
Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace W, et al. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity. 2010;33:71-83 pubmed publisher
Robles Carrillo L, Meyer T, Hatfield M, Desai H, Davila M, Langer F, et al. Anti-CD40L immune complexes potently activate platelets in vitro and cause thrombosis in FCGR2A transgenic mice. J Immunol. 2010;185:1577-83 pubmed publisher
Li J, Southerland L, Lu Y, Darlak K, Giver C, McMillin D, et al. Activation, immune polarization, and graft-versus-leukemia activity of donor T cells are regulated by specific subsets of donor bone marrow antigen-presenting cells in allogeneic hemopoietic stem cell transplantation. J Immunol. 2009;183:7799-809 pubmed publisher
Tusche M, Ward L, Vu F, McCarthy D, Quintela Fandino M, Ruland J, et al. Differential requirement of MALT1 for BAFF-induced outcomes in B cell subsets. J Exp Med. 2009;206:2671-83 pubmed publisher
Franchi L, Eigenbrod T, Nunez G. Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation. J Immunol. 2009;183:792-6 pubmed publisher
Izhak L, Wildbaum G, Zohar Y, Anunu R, Klapper L, Elkeles A, et al. A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2. J Immunol. 2009;183:732-9 pubmed publisher
Tsai C, Chiu Y, Hsu T, Lin I, Hsieh S, Lin K. Galectin-1 promotes immunoglobulin production during plasma cell differentiation. J Immunol. 2008;181:4570-9 pubmed
Kim T, Terwey T, Zakrzewski J, Suh D, Kochman A, Chen M, et al. Organ-derived dendritic cells have differential effects on alloreactive T cells. Blood. 2008;111:2929-40 pubmed publisher
Chen K, Iribarren P, Huang J, Zhang L, Gong W, Cho E, et al. Induction of the formyl peptide receptor 2 in microglia by IFN-gamma and synergy with CD40 ligand. J Immunol. 2007;178:1759-66 pubmed
Ito K, Takubo K, Arai F, Satoh H, Matsuoka S, Ohmura M, et al. Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes. J Immunol. 2007;178:103-10 pubmed
Yang Y, Ochando J, Yopp A, Bromberg J, Ding Y. IL-6 plays a unique role in initiating c-Maf expression during early stage of CD4 T cell activation. J Immunol. 2005;174:2720-9 pubmed
product information
Product Type :
Protein
Product Name :
Mouse CD40 Ligand (TNFSF5) (soluble) Recombinant Protein, PeproTech
Catalog # :
315-15-250UG
Quantity :
250 ug
Price :
US 1218.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Mouse
Applications :
Functional Assay: Assay-dependent
Species :
Mouse
Storage :
-20 C
Description :
CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
Format :
Lyophilized
Applications w/Dilutions :
Functional Assay: Assay-dependent
Aliases :
CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA