Human PD-L1 (B7-H1) Fc Recombinant Protein, PeproTech | Invitrogen 310-35-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human PD-L1 (B7-H1) Fc Recombinant Protein, PeproTech

catalog :

310-35-100UG

quantity :

100 ug

price :

US 226.00

citations: 2

Reference
Ogishi M, Yang R, Aytekin C, Langlais D, Bourgey M, Khan T, et al. Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child. Nat Med. 2021;: pubmed publisher
Li L, Jin X, Li J, Li C, Zhou S, Li J, et al. Systematic insight into the active constituents and mechanism of Guiqi Baizhu for the treatment of gastric cancer. Cancer Sci. 2021;112:1772-1784 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human PD-L1 (B7-H1) Fc Recombinant Protein, PeproTech

Catalog # :

310-35-100UG

Quantity :

100 ug

Price :

US 226.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.

Format :

Lyophilized

Applications w/Dilutions :

ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent

Aliases :

A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1