This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human CXCL13 (BLC/BCA-1) Recombinant Protein, PeproTech
catalog :
300-47-100UG
quantity :
100 ug
price :
US 692.00
citations: 25
Reference
Barington L, Christensen L, Pedersen K, Niss Arfelt K, Roumain M, Jensen K, et al. GPR183 Is Dispensable for B1 Cell Accumulation and Function, but Affects B2 Cell Abundance, in the Omentum and Peritoneal Cavity. Cells. 2022;11: pubmed publisher
Seda V, Vojackova E, Ondrisova L, Kostalova L, Sharma S, Loja T, et al. FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia. Blood. 2021;138:758-772 pubmed publisher
Gimenez N, Tripathi R, Giró A, Rosich L, Lopez Guerra M, López Oreja I, et al. Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia. Sci Rep. 2020;10:22153 pubmed publisher
Yasuoka H, Asai A, Ohama H, Tsuchimoto Y, Fukunishi S, Higuchi K. Increased both PD-L1 and PD-L2 expressions on monocytes of patients with hepatocellular carcinoma was associated with a poor prognosis. Sci Rep. 2020;10:10377 pubmed publisher
Curtaz C, Schmitt C, Herbert S, Feldheim J, Schlegel N, Gosselet F, et al. Serum-derived factors of breast cancer patients with brain metastases alter permeability of a human blood-brain barrier model. Fluids Barriers CNS. 2020;17:31 pubmed publisher
Lee A, Deruaz M, Lynch C, Davies G, Singh K, Alenazi Y, et al. A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. J Biol Chem. 2019;: pubmed publisher
Alenazi Y, Singh K, Davies G, Eaton J, Elders P, Kawamura A, et al. Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. Sci Rep. 2018;8:6333 pubmed publisher
Costa A, Kieffer Y, Scholer Dahirel A, Pelon F, Bourachot B, Cardon M, et al. Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer. Cancer Cell. 2018;33:463-479.e10 pubmed publisher
Singh K, Davies G, Alenazi Y, Eaton J, Kawamura A, Bhattacharya S. Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Sci Rep. 2017;7:4267 pubmed publisher
Balsas P, Palomero J, Eguileor A, Rodríguez M, Vegliante M, Planas Rigol E, et al. SOX11 promotes tumor protective microenvironment interactions through CXCR4 and FAK regulation in mantle cell lymphoma. Blood. 2017;130:501-513 pubmed publisher
Buskermolen J, Roffel S, Gibbs S. Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets. J Cell Physiol. 2017;232:2996-3005 pubmed publisher
Tsuchimoto Y, Asai A, Tsuda Y, Ito I, Nishiguchi T, Garcia M, et al. M2b Monocytes Provoke Bacterial Pneumonia and Gut Bacteria-Associated Sepsis in Alcoholics. J Immunol. 2015;195:5169-77 pubmed publisher
Beck T, Gomes A, Cyster J, Pereira J. CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow. J Exp Med. 2014;211:2567-81 pubmed publisher
Le Roux D, Le Bon A, Dumas A, Taleb K, Sachse M, Sikora R, et al. Antigen stored in dendritic cells after macropinocytosis is released unprocessed from late endosomes to target B cells. Blood. 2012;119:95-105 pubmed publisher
Chao M, Tang C, Pachynski R, Chin R, Majeti R, Weissman I. Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy. Blood. 2011;118:4890-901 pubmed publisher
Yung S, Parenti D, Murphy P. Host chemokines bind to Staphylococcus aureus and stimulate protein A release. J Biol Chem. 2011;286:5069-77 pubmed publisher
Kobayashi M, Jeschke M, Shigematsu K, Asai A, Yoshida S, Herndon D, et al. M2b monocytes predominated in peripheral blood of severely burned patients. J Immunol. 2010;185:7174-9 pubmed publisher
El Haibi C, Sharma P, Singh R, Johnson P, Suttles J, Singh S, et al. PI3Kp110-, Src-, FAK-dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer cells. Mol Cancer. 2010;9:85 pubmed publisher
Alley J, Bloom L, Kasaian M, Gao H, Berstein G, Clark J, et al. A human CXCL13-induced actin polymerization assay measured by fluorescence plate reader. Assay Drug Dev Technol. 2010;8:73-84 pubmed publisher
Trinidad E, Ballesteros M, Zuloaga J, Zapata A, Alonso Colmenar L. An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression. Blood. 2009;114:5081-90 pubmed publisher
Egesten A, Olin A, Linge H, Yadav M, M rgelin M, Karlsson A, et al. SpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines. PLoS ONE. 2009;4:e4769 pubmed publisher
Lim H, Lee J, Hillsamer P, Kim C. Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells. J Immunol. 2008;180:122-9 pubmed
Alejo A, Ruiz Argüello M, Ho Y, Smith V, Saraiva M, Alcami A. A chemokine-binding domain in the tumor necrosis factor receptor from variola (smallpox) virus. Proc Natl Acad Sci U S A. 2006;103:5995-6000 pubmed
Honczarenko M, Le Y, Swierkowski M, Ghiran I, Glodek A, Silberstein L. Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors. Stem Cells. 2006;24:1030-41 pubmed
Honczarenko M, Le Y, Glodek A, Majka M, Campbell J, Ratajczak M, et al. CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. Blood. 2002;100:2321-9 pubmed
product information
Product Type :
Protein
Product Name :
Human CXCL13 (BLC/BCA-1) Recombinant Protein, PeproTech
Catalog # :
300-47-100UG
Quantity :
100 ug
Price :
US 692.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
Species :
Human
Storage :
-20 C
Description :
CXCL13, also known as BCA-1 and Angie, is a small chemokine strongly expressed in the secondary lymphoid organs. It preferentially promotes the migration of B lymphocytes (both B-1 and B-2) to the follicles of the spleen, lymph nodes, and Peyer's patches. It is produced by macrophages, and in mouse the highest constitutive producers include large peritoneal macrophages, Kuppfer cells and lung macrophages (both CD11c+ and CD11c-). The cellular ligand for CXCL13 is CXCR5 also known as BLR-1 (Burkitt’s Lymphoma Receptor 1). CXCR5 is expressed on B cells, Tfh cells and, to a lower degree, some memory T cell populations. CXCL13 plays an important role in the development of chronic lymphocytic leukemia (CCL). CXCL13 is also a plasma biomarker for germinal center activity and generation of broadly neutralizing antibodies against HIV.
Format :
Lyophilized
Applications w/Dilutions :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
Aliases :
4631412M08Rik; Angie; ANGIE2; B cell-attracting chemokine 1; b lymphocyte chemoattractant; BCA1; BCA-1; B-cell chemoattractant; B-cell-attracting chemokine 1; B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1); BLC; BLR1L; B-lymphocyte chemoattractant; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chem; chemokine (C-X-C motif) ligand 13; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); CXC; CXC chemokine BLC; CXC motif chemokine; CXC motif chemokine 13; C-X-C motif chemokine 13; C-X-C motif chemokine ligand 13; CXCL; Cxcl13; SCYB13; small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant); small inducible cytokine subfamily B (Cys-X-Cys), member 13; small-inducible cytokine B13
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA