Human CCL11 (Eotaxin) Recombinant Protein, PeproTech | Invitrogen 300-21-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human CCL11 (Eotaxin) Recombinant Protein, PeproTech

catalog :

300-21-100UG

quantity :

100 ug

price :

US 696.00

citations: 24

Reference
Bouhaddou M, Memon D, Meyer B, White K, Rezelj V, Correa Marrero M, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020;182:685-712.e19 pubmed publisher
Lee A, Deruaz M, Lynch C, Davies G, Singh K, Alenazi Y, et al. A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. J Biol Chem. 2019;: pubmed publisher
Alenazi Y, Singh K, Davies G, Eaton J, Elders P, Kawamura A, et al. Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. Sci Rep. 2018;8:6333 pubmed publisher
Costa A, Kieffer Y, Scholer Dahirel A, Pelon F, Bourachot B, Cardon M, et al. Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer. Cancer Cell. 2018;33:463-479.e10 pubmed publisher
Zhang Y, Wu Y, Qi H, Xiao J, Gong H, Zhang Y, et al. A new antagonist for CCR4 attenuates allergic lung inflammation in a mouse model of asthma. Sci Rep. 2017;7:15038 pubmed publisher
Singh K, Davies G, Alenazi Y, Eaton J, Kawamura A, Bhattacharya S. Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Sci Rep. 2017;7:4267 pubmed publisher
Lessel D, Muhammad T, Casar Tena T, Moepps B, Burkhalter M, Hitz M, et al. The analysis of heterotaxy patients reveals new loss-of-function variants of GRK5. Sci Rep. 2016;6:33231 pubmed publisher
Konya V, Blättermann S, Jandl K, Platzer W, Ottersbach P, Marsche G, et al. A biased non-G?i OXE-R antagonist demonstrates that G?i protein subunit is not directly involved in neutrophil, eosinophil, and monocyte activation by 5-oxo-ETE. J Immunol. 2014;192:4774-82 pubmed publisher
Pazdrak K, Young T, Straub C, Stafford S, Kurosky A. Priming of eosinophils by GM-CSF is mediated by protein kinase CbetaII-phosphorylated L-plastin. J Immunol. 2011;186:6485-96 pubmed publisher
Yung S, Parenti D, Murphy P. Host chemokines bind to Staphylococcus aureus and stimulate protein A release. J Biol Chem. 2011;286:5069-77 pubmed publisher
Clements D, Markwick L, Puri N, Johnson S. Role of the CXCR4/CXCL12 axis in lymphangioleiomyomatosis and angiomyolipoma. J Immunol. 2010;185:1812-21 pubmed publisher
Izhak L, Wildbaum G, Zohar Y, Anunu R, Klapper L, Elkeles A, et al. A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2. J Immunol. 2009;183:732-9 pubmed publisher
Takeda A, Baffi J, Kleinman M, Cho W, Nozaki M, Yamada K, et al. CCR3 is a target for age-related macular degeneration diagnosis and therapy. Nature. 2009;460:225-30 pubmed publisher
Sturm E, Schratl P, Schuligoi R, Konya V, Sturm G, Lippe I, et al. Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors. J Immunol. 2008;181:7273-83 pubmed
Spiegl N, Didichenko S, McCaffery P, Langen H, Dahinden C. Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid. Blood. 2008;112:3762-71 pubmed publisher
Ponte A, Marais E, Gallay N, Langonne A, Delorme B, Herault O, et al. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells. 2007;25:1737-45 pubmed
Munitz A, Bachelet I, Eliashar R, Moretta A, Moretta L, Levi Schaffer F. The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils. Blood. 2006;107:1996-2003 pubmed
Howard O, Dong H, Su S, Caspi R, Chen X, Plotz P, et al. Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate. Blood. 2005;105:4207-14 pubmed
Hartnell A, Heinemann A, Conroy D, Wait R, Sturm G, Caversaccio M, et al. Identification of selective basophil chemoattractants in human nasal polyps as insulin-like growth factor-1 and insulin-like growth factor-2. J Immunol. 2004;173:6448-57 pubmed
Ferland C, Flamand N, Davoine F, Chakir J, Laviolette M. IL-16 activates plasminogen-plasmin system and promotes human eosinophil migration into extracellular matrix via CCR3-chemokine-mediated signaling and by modulating CD4 eosinophil expression. J Immunol. 2004;173:4417-24 pubmed
Bryan S, Jose P, Topping J, Wilhelm R, Soderberg C, Kertesz D, et al. Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists. Am J Respir Crit Care Med. 2002;165:1602-9 pubmed
Sabroe I, Peck M, Van Keulen B, Jorritsma A, Simmons G, Clapham P, et al. A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry. J Biol Chem. 2000;275:25985-92 pubmed
Elsner J, Mack M, Bruhl H, Dulkys Y, Kimmig D, Simmons G, et al. Differential activation of CC chemokine receptors by AOP-RANTES. J Biol Chem. 2000;275:7787-94 pubmed
Struyf S, Proost P, Schols D, De Clercq E, Opdenakker G, Lenaerts J, et al. CD26/dipeptidyl-peptidase IV down-regulates the eosinophil chemotactic potency, but not the anti-HIV activity of human eotaxin by affecting its interaction with CC chemokine receptor 3. J Immunol. 1999;162:4903-9 pubmed

product information

Product Type :

Protein

Product Name :

Human CCL11 (Eotaxin) Recombinant Protein, PeproTech

Catalog # :

300-21-100UG

Quantity :

100 ug

Price :

US 696.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Format :

Lyophilized

Applications w/Dilutions :

ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent

Aliases :

C-C motif chemokine 11; C-C motif chemokine ligand 11; Ccl11; chemokine (C-C motif) ligand 11; eosinophil chemotactic protein; Eotaxin; Eotaxin 1; Eotaxin1; eotaxin-1; MGC22554; Scya11; small chemokine (C-C motif) ligand 11; small inducible cytokine A11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); small inducible cytokine subfamily A11; small-inducible cytokine A11