Human Oncostatin M (209 aa) Recombinant Protein, PeproTech | Invitrogen 300-10T-500UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human Oncostatin M (209 aa) Recombinant Protein, PeproTech

catalog :

300-10T-500UG

quantity :

500 ug

price :

US 3615.00

citations: 16

Reference
Niehues H, Rikken G, van Vlijmen Willems I, Rodijk Olthuis D, van Erp P, Zeeuwen P, et al. Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis. JID Innov. 2022;2:100066 pubmed publisher
Mass O, Tuccinardi J, Woodbury L, Wolf C, Grantham B, Holdaway K, et al. Bioactive recombinant human oncostatin M for NMR-based screening in drug discovery. Sci Rep. 2021;11:16174 pubmed publisher
Bogacheva M, Bystriakova M, Lou Y. Thyroid Hormone Effect on the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells. Pharmaceuticals (Basel). 2021;14: pubmed publisher
Hara T, Chanoch Myers R, Mathewson N, Myskiw C, Atta L, Bussema L, et al. Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma. Cancer Cell. 2021;39:779-792.e11 pubmed publisher
Passaretta F, Bosco D, Centurione L, Centurione M, Marongiu F, Di Pietro R. Differential response to hepatic differentiation stimuli of amniotic epithelial cells isolated from four regions of the amniotic membrane. J Cell Mol Med. 2020;24:4350-4355 pubmed publisher
Palakkan A, Nanda J, Ross J. Human Induced Pluripotent Stem Cell-Derived Definitive Endoderm Bulk Culture and Hepatic Differentiation. Methods Mol Biol. 2019;1994:41-53 pubmed publisher
Tawara K, Scott H, Emathinger J, Wolf C, LaJoie D, Hedeen D, et al. HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β. Oncotarget. 2019;10:2068-2085 pubmed publisher
Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed publisher
Edsbäcker E, Serviss J, Kolosenko I, Palm Apergi C, De Milito A, Tamm K. STAT3 is activated in multicellular spheroids of colon carcinoma cells and mediates expression of IRF9 and interferon stimulated genes. Sci Rep. 2019;9:536 pubmed publisher
Fu G, Huang W, Zeng M, Zhou X, Wu H, Liu C, et al. Expansion and differentiation of human hepatocyte-derived liver progenitor-like cells and their use for the study of hepatotropic pathogens. Cell Res. 2019;29:8-22 pubmed publisher
Fan J, Lee H, Lee W, Lin C, Hsu C, Hsieh C, et al. Potential role of CBX7 in regulating pluripotency of adult human pluripotent-like olfactory stem cells in stroke model. Cell Death Dis. 2018;9:502 pubmed publisher
Shee K, Yang W, Hinds J, Hampsch R, Varn F, Traphagen N, et al. Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. J Exp Med. 2018;215:895-910 pubmed publisher
Jones G, Moschidou D, Puga Iglesias T, Kuleszewicz K, Vanleene M, Shefelbine S, et al. Ontological differences in first compared to third trimester human fetal placental chorionic stem cells. PLoS ONE. 2012;7:e43395 pubmed publisher
Moschidou D, Mukherjee S, Blundell M, Drews K, Jones G, Abdulrazzak H, et al. Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach. Mol Ther. 2012;20:1953-67 pubmed publisher
Bone H, Nelson A, Goldring C, Tosh D, Welham M. A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3. J Cell Sci. 2011;124:1992-2000 pubmed publisher
Mendez Ferrer S, Michurina T, Ferraro F, Mazloom A, MacArthur B, Lira S, et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature. 2010;466:829-34 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human Oncostatin M (209 aa) Recombinant Protein, PeproTech

Catalog # :

300-10T-500UG

Quantity :

500 ug

Price :

US 3615.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Functional Assay: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.

Format :

Lyophilized

Applications w/Dilutions :

Functional Assay: Assay-dependent

Aliases :

MGC20461; OncoM; oncostatin M; oncostatin-M; OSM