This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Mouse CXCL12 (SDF-1a) Recombinant Protein, PeproTech
catalog :
250-20A-50UG
quantity :
50 ug
price :
US 417.00
citations: 162
Reference
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Liu X, Zhou C, Li Y, Ji Y, Xu G, Wang X, et al. SDF-1 promotes endochondral bone repair during fracture healing at the traumatic brain injury condition. PLoS ONE. 2013;8:e54077 pubmed publisher
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Inngjerdingen M, Kveberg L, Vaage J. A novel NKR-P1B(bright) NK cell subset expresses an activated CD25(+)CX(3)CR1(+)CD62L(-)CD11b(-)CD27(-) phenotype and is prevalent in blood, liver, and gut-associated lymphoid organs of rats. J Immunol. 2012;188:2499-508 pubmed publisher
Wang C, Lee J, Kim C. Optimal population of FoxP3+ T cells in tumors requires an antigen priming-dependent trafficking receptor switch. PLoS ONE. 2012;7:e30793 pubmed publisher
Kew R, Penzo M, Habiel D, Marcu K. The IKK?-dependent NF-?B p52/RelB noncanonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1. J Immunol. 2012;188:2380-6 pubmed publisher
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Kostyak J, Naik M, Naik U. Calcium- and integrin-binding protein 1 regulates megakaryocyte ploidy, adhesion, and migration. Blood. 2012;119:838-46 pubmed publisher
Liu Y, Belkina N, Park C, Nambiar R, Loughhead S, Patino Lopez G, et al. Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice. Blood. 2012;119:445-53 pubmed publisher
Jones S, White C, Robb L, Alexander W, Tarlinton D. SOCS3 deletion in B cells alters cytokine responses and germinal center output. J Immunol. 2011;187:6318-26 pubmed publisher
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Bernal A, San Martin N, Fernandez M, Covarello D, Molla F, Soldo A, et al. L-selectin and SDF-1 enhance the migration of mouse and human cardiac mesoangioblasts. Cell Death Differ. 2012;19:345-55 pubmed publisher
Kelly L, Pereira J, Yi T, Xu Y, Cyster J. EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues. J Immunol. 2011;187:3026-32 pubmed publisher
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Dehring D, Clarke F, Ricart B, Huang Y, Gomez T, Williamson E, et al. Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cells. J Immunol. 2011;186:4805-18 pubmed publisher
Mazharian A, Ghevaert C, Zhang L, Massberg S, Watson S. Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation. Blood. 2011;117:5198-206 pubmed publisher
Chow A, Lucas D, Hidalgo A, Mendez Ferrer S, Hashimoto D, Scheiermann C, et al. Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. J Exp Med. 2011;208:261-71 pubmed publisher
Islam S, Chang D, Colvin R, Byrne M, McCully M, Moser B, et al. Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells. Nat Immunol. 2011;12:167-77 pubmed publisher
Hartman N, Carpentino J, Lamonica K, Mor D, Naegele J, Grabel L. CXCL12-mediated guidance of migrating embryonic stem cell-derived neural progenitors transplanted into the hippocampus. PLoS ONE. 2010;5:e15856 pubmed publisher
Cronshaw D, Nie Y, Waite J, Zou Y. An essential role of the cytoplasmic tail of CXCR4 in G-protein signaling and organogenesis. PLoS ONE. 2010;5:e15397 pubmed publisher
Ricart B, John B, Lee D, Hunter C, Hammer D. Dendritic cells distinguish individual chemokine signals through CCR7 and CXCR4. J Immunol. 2011;186:53-61 pubmed publisher
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Jung Y, Rutishauser R, Joshi N, Haberman A, Kaech S. Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection. J Immunol. 2010;185:5315-25 pubmed publisher
Arthur J, Lich J, Ye Z, Allen I, Gris D, Wilson J, et al. Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. J Immunol. 2010;185:4515-9 pubmed publisher
Lai J, Wlodarska M, Liu D, Abraham N, Johnson P. CD45 regulates migration, proliferation, and progression of double negative 1 thymocytes. J Immunol. 2010;185:2059-70 pubmed publisher
Scielzo C, Bertilaccio M, Simonetti G, Dagklis A, ten Hacken E, Fazi C, et al. HS1 has a central role in the trafficking and homing of leukemic B cells. Blood. 2010;116:3537-46 pubmed publisher
Al Shami A, Wilkins C, Crisostomo J, Seshasayee D, Martin F, Xu N, et al. The adaptor protein Sh2d3c is critical for marginal zone B cell development and function. J Immunol. 2010;185:327-34 pubmed publisher
Marlow R, Binnewies M, Sorensen L, Monica S, Strickland P, Forsberg E, et al. Vascular Robo4 restricts proangiogenic VEGF signaling in breast. Proc Natl Acad Sci U S A. 2010;107:10520-5 pubmed publisher
Mazharian A, Thomas S, Dhanjal T, Buckley C, Watson S. Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis. Blood. 2010;116:793-800 pubmed publisher
Berge T, Sundvold Gjerstad V, Granum S, Andersen T, Holthe G, Claesson Welsh L, et al. T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells. PLoS ONE. 2010;5:e9761 pubmed publisher
Nguyen Jackson H, Panopoulos A, Zhang H, Li H, Watowich S. STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction. Blood. 2010;115:3354-63 pubmed publisher
Treanor B, Depoil D, Gonzalez Granja A, Barral P, Weber M, Dushek O, et al. The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor. Immunity. 2010;32:187-99 pubmed publisher
Zetterblad J, Qian H, Zandi S, Mansson R, Lagergren A, Hansson F, et al. Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication. BMC Genomics. 2010;11:108 pubmed publisher
Janas M, Varano G, Gudmundsson K, Noda M, Nagasawa T, Turner M. Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4. J Exp Med. 2010;207:247-61 pubmed publisher
Wang L, Wang Y, Hu X, Zhang B, Dou G, He F, et al. Notch-RBP-J signaling regulates the mobilization and function of endothelial progenitor cells by dynamic modulation of CXCR4 expression in mice. PLoS ONE. 2009;4:e7572 pubmed publisher
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product information
Product Type :
Protein
Product Name :
Mouse CXCL12 (SDF-1a) Recombinant Protein, PeproTech
Catalog # :
250-20A-50UG
Quantity :
50 ug
Price :
US 417.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Mouse
Applications :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
Species :
Mouse
Storage :
-20 C
Description :
CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
Format :
Lyophilized
Applications w/Dilutions :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
Aliases :
12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; H-SDF-1-alpha; Intercrine reduced in hepatomas; IRH; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; SDF 1 a; SDF 1 alpha; SDF 1a; SDF1; SDF-1; SDF1 alpha; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); SDF1a; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA