KLRG1 Monoclonal Antibody (13F12F2), PE-Cyanine7, eBioscience | Invitrogen 25-9488-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KLRG1 Monoclonal Antibody (13F12F2), PE-Cyanine7, eBioscience

catalog :

25-9488-42

quantity :

100 Tests

price :

US 475.00

clonality :

monoclonal

host :

mouse

conjugate :

PE/Cy7

clone name :

13F12F2

reactivity :

human

application :

flow cytometry

citations: 10

Reference
Yang J, Liu H, Zhang J, Zou J, Zhang X, Chen W, et al. The effect of metformin on senescence of T lymphocytes. Immun Ageing. 2023;20:73 pubmed publisher
Jung S, Jung J, Noh J, Kim W, Yoon S, Jung J, et al. The generation of stem cell-like memory cells early after BNT162b2 vaccination is associated with durability of memory CD8+ T cell responses. Cell Rep. 2022;40:111138 pubmed publisher
Nie Y, Liu D, Yang W, Li Y, Zhang L, Cheng X, et al. Increased expression of TIGIT and KLRG1 correlates with impaired CD56bright NK cell immunity in HPV16-related cervical intraepithelial neoplasia. Virol J. 2022;19:68 pubmed publisher
Corgnac S, Lecluse Y, Mami Chouaib F. Isolation of tumor-resident CD8+ T cells from human lung tumors. STAR Protoc. 2021;2:100267 pubmed publisher
Rha M, Jeong H, Ko J, Choi S, Seo I, Lee J, et al. PD-1-Expressing SARS-CoV-2-Specific CD8+ T Cells Are Not Exhausted, but Functional in Patients with COVID-19. Immunity. 2021;54:44-52.e3 pubmed publisher
Golebski K, Ros X, Nagasawa M, van Tol S, Heesters B, Aglmous H, et al. IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation. Nat Commun. 2019;10:2162 pubmed publisher
Harms Pritchard G, Hall A, Christian D, Wagage S, Fang Q, Muallem G, et al. Diverse roles for T-bet in the effector responses required for resistance to infection. J Immunol. 2015;194:1131-40 pubmed publisher
Puleston D, Zhang H, Powell T, Lipina E, Sims S, Panse I, et al. Autophagy is a critical regulator of memory CD8(+) T cell formation. elife. 2014;3: pubmed publisher
Beus J, Hashmi S, Selvaraj S, Duan D, Stempora L, Monday S, et al. Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection. PLoS ONE. 2013;8:e71221 pubmed publisher
Chang P, Lee S, Hu X, Davey G, Duan G, Cho J, et al. Breakdown in repression of IFN-? mRNA leads to accumulation of self-reactive effector CD8+ T cells. J Immunol. 2012;189:701-10 pubmed publisher

product information

Product Type :

Antibody

Product Name :

KLRG1 Monoclonal Antibody (13F12F2), PE-Cyanine7, eBioscience

Catalog # :

25-9488-42

Quantity :

100 Tests

Price :

US 475.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.06 ug)/test

Species :

Human

Clone :

13F12F2

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.06 ug)/test

Aliases :

2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor