IDO Monoclonal Antibody (eyedio), PE-Cyanine7, eBioscience | Invitrogen 25-9477-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IDO Monoclonal Antibody (eyedio), PE-Cyanine7, eBioscience

catalog :

25-9477-42

quantity :

100 Tests

price :

US 394.00

clonality :

monoclonal

host :

mouse

conjugate :

PE/Cy7

clone name :

eyedio

reactivity :

human

application :

flow cytometry

citations: 7

Reference
Suzuki T, Iizuka T, Kagami K, Matsumoto T, Yamazaki R, Daikoku T, et al. Laeverin/aminopeptidase Q induces indoleamine 2,3-dioxygenase-1 in human monocytes. iScience. 2023;26:107692 pubmed publisher
Asano A, Ri M, Masaki A, Maeda Y, Tachita T, Hirade K, et al. Aberrant tryptophan metabolism leads to unfavorable outcomes in lenalidomide-treated myeloma patients. Hematol Oncol. 2023;41:424-433 pubmed publisher
Maassen S, Warner H, Ioannidis M, Jansma J, Markus H, El Aidy S, et al. Mitochondrial interaction of fibrosis-protective 5-methoxy tryptophan enhances collagen uptake by macrophages. Free Radic Biol Med. 2022;188:287-297 pubmed publisher
Mebarki M, Iglicki N, Marigny C, Abadie C, Nicolet C, Churlaud G, et al. Development of a human umbilical cord-derived mesenchymal stromal cell-based advanced therapy medicinal product to treat immune and/or inflammatory diseases. Stem Cell Res Ther. 2021;12:571 pubmed publisher
Li Q, Li X, Quan H, Wang Y, Qu G, Shen Z, et al. IL-10-/- Enhances DCs Immunity Against Chlamydia psittaci Infection via OX40L/NLRP3 and IDO/Treg Pathways. Front Immunol. 2021;12:645653 pubmed publisher
Behm C, Blufstein A, Gahn J, Kubin B, Moritz A, Rausch fan X, et al. Continuing Effect of Cytokines and Toll-Like Receptor Agonists on Indoleamine-2,3-Dioxygenase-1 in Human Periodontal Ligament Stem/Stromal Cells. Cells. 2020;9: pubmed publisher
García González P, Schinnerling K, Sepúlveda Gutiérrez A, Maggi J, Mehdi A, Nel H, et al. Dexamethasone and Monophosphoryl Lipid A Induce a Distinctive Profile on Monocyte-Derived Dendritic Cells through Transcriptional Modulation of Genes Associated With Essential Processes of the Immune Response. Front Immunol. 2017;8:1350 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IDO Monoclonal Antibody (eyedio), PE-Cyanine7, eBioscience

Catalog # :

25-9477-42

Quantity :

100 Tests

Price :

US 394.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.06 ug)/test

Species :

Human

Clone :

eyedio

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules like tryptophan, serotonin, and melatonin. By doing this, IDO1 initiates the production of biologically active metabolites, commonly referred to as kynurenines. IDO1 is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs). In inflammation, interferons (IFNs) act on specific receptors to trigger IDO1 induction. The production of IFN-gamma and induction of IDO1 represent important antimicrobial mechanisms. Degradation and depletion of tryptophan by IDO1 inhibits the growth of viruses, bacteria and parasites. Furthermore, IDO1 plays a complex and crucial role in immunoregulation during infection, pregnancy, autoimmunity, transplantation, and neoplasia.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.06 ug)/test

Aliases :

EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase