product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IFN gamma Monoclonal Antibody (XMG1.2), PE-Cyanine7, eBioscience™
catalog :
25-7311-41
quantity :
25 Tests
price :
US 309.00
clonality :
monoclonal
host :
rat
conjugate :
PE/Cy7
clone name :
XMG1.2
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 133
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:100; loading ...; fig 5
Ward L, Lee D, Sharma A, Wang A, Naouar I, Ma X, et al. Siponimod therapy implicates Th17 cells in a preclinical model of subpial cortical injury. JCI Insight. 2020;5: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Hang S, Paik D, Yao L, Kim E, Jamma T, Lu J, et al. Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2019;576:143-148 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 3d
Ma L, Dichwalkar T, Chang J, Cossette B, Garafola D, Zhang A, et al. Enhanced CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor. Science. 2019;365:162-168 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b, 2c
Karmaus P, Chen X, Lim S, Herrada A, Nguyen T, Xu B, et al. Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity. Nature. 2019;565:101-105 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4b
Song M, Sandoval T, Chae C, Chopra S, Tan C, Rutkowski M, et al. IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. Nature. 2018;562:423-428 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Stathopoulou C, Gangaplara A, Mallett G, Flomerfelt F, Liniany L, Knight D, et al. PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells. Immunity. 2018;49:247-263.e7 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Jogdand G, Sengupta S, Bhattacharya G, Singh S, Barik P, Devadas S. Inducible Costimulator Expressing T Cells Promote Parasitic Growth During Blood Stage Plasmodium berghei ANKA Infection. Front Immunol. 2018;9:1041 pubmed publisher
  • flow cytometry; mouse; loading ...; fig e4b
Du X, Wen J, Wang Y, Karmaus P, Khatamian A, Tan H, et al. Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells. Nature. 2018;558:141-145 pubmed publisher
  • flow cytometry; mouse; fig 3b
Tavazoie M, Pollack I, Tanqueco R, Ostendorf B, Reis B, Gonsalves F, et al. LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer. Cell. 2018;172:825-840.e18 pubmed publisher
  • flow cytometry; mouse; fig 3b
Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018;172:517-533.e20 pubmed publisher
  • flow cytometry; mouse; fig 2
Patel M, Kim J, Theodros D, Tam A, Velarde E, Kochel C, et al. Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma. J Immunother Cancer. 2016;4:28 pubmed publisher
  • flow cytometry; mouse; fig 6
Tosiek M, Fiette L, El Daker S, Eberl G, Freitas A. IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease. Nat Commun. 2016;7:10888 pubmed publisher
  • flow cytometry; human; fig 3
Chen H, Sun J, Huang Z, Hou H, Arcilla M, Rakhilin N, et al. Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting. Nat Biotechnol. 2015;33:656-60 pubmed publisher
  • flow cytometry; mouse
Longman R, Diehl G, Victorio D, Huh J, Galan C, Miraldi E, et al. CX?CR1? mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. J Exp Med. 2014;211:1571-83 pubmed publisher
  • flow cytometry; mouse; fig 2
Matsuda J, Zhang Q, Ndonye R, Richardson S, Howell A, Gapin L. T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells. Blood. 2006;107:2797-805 pubmed
Chong W, Mattapallil M, Raychaudhuri K, Bing S, Wu S, Zhong Y, et al. The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24. Immunity. 2020;53:384-397.e5 pubmed publisher
Sisteré Oró M, Pedersen G, Cordoba L, López Serrano S, Christensen D, Darji A. Influenza NG-34 T cell conserved epitope adjuvanted with CAF01 as a possible influenza vaccine candidate. Vet Res. 2020;51:57 pubmed publisher
Klepsch V, Pommermayr M, Humer D, Brigo N, Hermann Kleiter N, Baier G. Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy. Cell Commun Signal. 2020;18:8 pubmed publisher
Chang L, Wang L, Ling N, Peng H, Chen M. Increase in liver γδ T cells with concurrent augmentation of IFN-β production during the early stages of a mouse model of acute experimental hepatitis B virus infection. Exp Ther Med. 2020;19:67-78 pubmed publisher
Shi L, Wang J, Ding N, Zhang Y, Zhu Y, Dong S, et al. Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy. Nat Commun. 2019;10:5421 pubmed publisher
Xu J, Pei S, Wang Y, Liu J, Qian Y, Huang M, et al. Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells. Front Immunol. 2019;10:1980 pubmed publisher
Fu Z, Ye J, Dean J, Bostick J, Weinberg S, Xiong L, et al. Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function. Cell Rep. 2019;28:159-171.e4 pubmed publisher
David S, Norton T, Tyllis T, Wilson J, Singleton E, Laan Z, et al. Direct interaction of whole-inactivated influenza A and pneumococcal vaccines enhances influenza-specific immunity. Nat Microbiol. 2019;: pubmed publisher
Anderson C, Reilly E, Lee A, Brossay L. Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection. Cell Rep. 2019;27:537-548.e5 pubmed publisher
Bhatia S, Oweida A, Lennon S, Darragh L, Milner D, Phan A, et al. Inhibition of EphB4-Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers. Cancer Res. 2019;79:2722-2735 pubmed publisher
Orr M, Khandhar A, Seydoux E, Liang H, Gage E, Mikasa T, et al. Reprogramming the adjuvant properties of aluminum oxyhydroxide with nanoparticle technology. NPJ Vaccines. 2019;4:1 pubmed publisher
Scheer S, Ackloo S, Medina T, Schapira M, Li F, Ward J, et al. A chemical biology toolbox to study protein methyltransferases and epigenetic signaling. Nat Commun. 2019;10:19 pubmed publisher
Liu Z, Ge Y, Wang H, Ma C, Feist M, Ju S, et al. Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2. Nat Commun. 2018;9:4682 pubmed publisher
Chandra S, Gray J, Kiosses W, Khurana A, Hitomi K, Crosby C, et al. Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae. Nat Commun. 2018;9:4279 pubmed publisher
Cheng Y, Zhu X, Wang X, Zhuang Q, Huyan X, Sun X, et al. Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation. Front Immunol. 2018;9:1566 pubmed publisher
Osorio Barrios F, Prado C, Contreras F, Pacheco R. Dopamine Receptor D5 Signaling Plays a Dual Role in Experimental Autoimmune Encephalomyelitis Potentiating Th17-Mediated Immunity and Favoring Suppressive Activity of Regulatory T-Cells. Front Cell Neurosci. 2018;12:192 pubmed publisher
Hirota K, Hashimoto M, Ito Y, Matsuura M, Ito H, Tanaka M, et al. Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis. Immunity. 2018;48:1220-1232.e5 pubmed publisher
Mukherjee R, Moreno Fernandez M, Giles D, Cappelletti M, Stankiewicz T, Chan C, et al. Nicotinamide adenine dinucleotide phosphate (reduced) oxidase 2 modulates inflammatory vigor during nonalcoholic fatty liver disease progression in mice. Hepatol Commun. 2018;2:546-560 pubmed publisher
Pang P, Zheng K, Wu S, Xü H, Deng L, Shi Y, et al. Baicalin Downregulates RLRs Signaling Pathway to Control Influenza A Virus Infection and Improve the Prognosis. Evid Based Complement Alternat Med. 2018;2018:4923062 pubmed publisher
Gabryšová L, Alvarez Martinez M, Luisier R, Cox L, Sodenkamp J, Hosking C, et al. c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells. Nat Immunol. 2018;19:497-507 pubmed publisher
Sun C, Lan P, Han Q, Huang M, Zhang Z, Xu G, et al. Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion. Nat Commun. 2018;9:1241 pubmed publisher
Moreno Fernandez M, Giles D, Stankiewicz T, Sheridan R, Karns R, Cappelletti M, et al. Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease. JCI Insight. 2018;3: pubmed publisher
Kim D, Park H, Lim S, Koo J, Lee H, Choi J, et al. Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis. Nat Commun. 2018;9:503 pubmed publisher
Lu Y, Kim N, Jiang Y, Zhang H, Zheng D, Zhu F, et al. Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function. Br J Pharmacol. 2018;175:1085-1099 pubmed publisher
Ano Y, Ikado K, Shindo K, Koizumi H, Fujiwara D. Identification of 14-dehydroergosterol as a novel anti-inflammatory compound inducing tolerogenic dendritic cells. Sci Rep. 2017;7:13903 pubmed publisher
Deng R, Hurtz C, Song Q, Yue C, Xiao G, Yu H, et al. Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease. Nat Commun. 2017;8:978 pubmed publisher
Chu F, Hu Y, Zhou Y, Guo M, Lu J, Zheng W, et al. MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway. Clin Exp Immunol. 2017;: pubmed publisher
Wang H, Li J, Han Q, Yang F, Xiao Y, Xiao M, et al. IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis. Int J Med Sci. 2017;14:977-983 pubmed publisher
Robert R, Ang C, Sun G, Juglair L, Lim E, Mason L, et al. Essential role for CCR6 in certain inflammatory diseases demonstrated using specific antagonist and knockin mice. JCI Insight. 2017;2: pubmed publisher
Ma J, Teng X, Wang X, Fan X, Wu Y, Tian M, et al. A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation. EBioMedicine. 2017;22:143-154 pubmed publisher
Pardo E, Cárcamo C, Uribe San Martin R, Ciampi E, Segovia Miranda F, Curkovic Peña C, et al. Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis. PLoS ONE. 2017;12:e0177472 pubmed publisher
Yu Q, Wang X, Fan X. A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells. Front Immunol. 2017;8:585 pubmed publisher
Friedrich C, Mamareli P, Thiemann S, Kruse F, Wang Z, Holzmann B, et al. MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium. PLoS Pathog. 2017;13:e1006357 pubmed publisher
Miao T, Symonds A, Singh R, Symonds J, Ogbe A, Omodho B, et al. Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation. J Exp Med. 2017;214:1787-1808 pubmed publisher
Cui N, Wang H, Su L, Zhang J, Long Y, Liu D. Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis. Chin Med J (Engl). 2017;130:1211-1217 pubmed publisher
Clemmensen H, Knudsen N, Rasmussen E, Winkler J, Rosenkrands I, Ahmad A, et al. An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathology. Sci Rep. 2017;7:46666 pubmed publisher
Li Y, Liu X, Duan W, Tian H, Zhu G, He H, et al. Batf3-dependent CD8?+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages. EBioMedicine. 2017;18:188-198 pubmed publisher
Allen E, Jabouille A, Rivera L, Lodewijckx I, Missiaen R, Steri V, et al. Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation. Sci Transl Med. 2017;9: pubmed publisher
Cho J, Lee H, Ko H, Yoon B, Choe J, Kim K, et al. The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma. Oncotarget. 2017;8:24932-24948 pubmed publisher
Ying W, Wollam J, Ofrecio J, Bandyopadhyay G, El Ouarrat D, Lee Y, et al. Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling. J Clin Invest. 2017;127:1019-1030 pubmed publisher
Zhang H, Qi Y, Yuan Y, Cai L, Xu H, Zhang L, et al. Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation. Sci Rep. 2017;7:41887 pubmed publisher
Berlato C, Khan M, Schioppa T, Thompson R, Maniati E, Montfort A, et al. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. J Clin Invest. 2017;127:801-813 pubmed publisher
Yu H, Park M, Kang S, Cho K, Mun S, Roh H. Culture supernatant of adipose stem cells can ameliorate allergic airway inflammation via recruitment of CD4+CD25+Foxp3 T cells. Stem Cell Res Ther. 2017;8:8 pubmed publisher
Cruz L, Hashemifar S, Wu C, Cho S, Nguyen D, Lin L, et al. Excessive expression of miR-27 impairs Treg-mediated immunological tolerance. J Clin Invest. 2017;127:530-542 pubmed publisher
Aguilera T, Rafat M, Castellini L, Shehade H, Kariolis M, Hui A, et al. Reprogramming the immunological microenvironment through radiation and targeting Axl. Nat Commun. 2016;7:13898 pubmed publisher
Zhou Y, Weng X, Dou R, Tan X, Zhang T, Fang J, et al. Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice. Acta Pharmacol Sin. 2017;38:201-210 pubmed publisher
Chudnovskiy A, Mortha A, Kana V, Kennard A, Ramírez J, Rahman A, et al. Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome. Cell. 2016;167:444-456.e14 pubmed publisher
Perobelli S, Mercadante A, Galvani R, Gonçalves Silva T, Alves A, Pereira Neves A, et al. G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way. J Immunol. 2016;197:3725-3734 pubmed
Gerriets V, Kishton R, Johnson M, Cohen S, Siska P, Nichols A, et al. Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression. Nat Immunol. 2016;17:1459-1466 pubmed publisher
Yang M, Chen S, Du J, He J, Wang Y, Li Z, et al. NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. Nat Commun. 2016;7:12730 pubmed publisher
Clever D, Roychoudhuri R, Constantinides M, Askenase M, Sukumar M, Klebanoff C, et al. Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche. Cell. 2016;166:1117-1131.e14 pubmed publisher
Seedhom M, Hickman H, Wei J, David A, Yewdell J. Protein Translation Activity: A New Measure of Host Immune Cell Activation. J Immunol. 2016;197:1498-506 pubmed publisher
Yang E, Singh B, Paustian A, Kambayashi T. Diacylglycerol Kinase ? Is a Target To Enhance NK Cell Function. J Immunol. 2016;197:934-41 pubmed publisher
Haddad C, Bhattacharya P, Alharshawi K, Marinelarena A, Kumar P, El Sayed O, et al. Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice. Autoimmunity. 2016;49:298-311 pubmed publisher
Tibbitt C, Falconer J, Stoop J, van Eden W, Robinson J, Hilkens C. Reduced TCR-dependent activation through citrullination of a T-cell epitope enhances Th17 development by disruption of the STAT3/5 balance. Eur J Immunol. 2016;46:1633-43 pubmed publisher
Tian Y, Kuo C, Akbari O, Ou J. Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission. Immunity. 2016;44:1204-14 pubmed publisher
Wu C, Liu S, Chen H, Shen K, Leng C. A Toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory T cells population. Oncotarget. 2016;7:30804-19 pubmed publisher
Salao K, Jiang L, Li H, Tsai V, Husaini Y, Curmi P, et al. CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis. Biol Open. 2016;5:620-30 pubmed publisher
Christensen D, Mortensen R, Rosenkrands I, Dietrich J, Andersen P. Vaccine-induced Th17 cells are established as resident memory cells in the lung and promote local IgA responses. Mucosal Immunol. 2017;10:260-270 pubmed publisher
Qi X, Gurung P, Malireddi R, Karmaus P, Sharma D, Vogel P, et al. Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis. Mucosal Immunol. 2017;10:128-138 pubmed publisher
Noble A, Mehta H, Lovell A, Papaioannou E, Fairbanks L. IL-12 and IL-4 activate a CD39-dependent intrinsic peripheral tolerance mechanism in CD8(+) T cells. Eur J Immunol. 2016;46:1438-48 pubmed publisher
Yang L, Cai C, Feng Q, Shi Y, Zuo Q, Yang H, et al. Protective efficacy of the chimeric Staphylococcus aureus vaccine candidate IC in sepsis and pneumonia models. Sci Rep. 2016;6:20929 pubmed publisher
Ying W, Tseng A, Chang R, Wang H, Lin Y, Kanameni S, et al. miR-150 regulates obesity-associated insulin resistance by controlling B cell functions. Sci Rep. 2016;6:20176 pubmed publisher
Singh S, Vedi S, Samrat S, Li W, Kumar R, Agrawal B. Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines. PLoS ONE. 2016;11:e0146404 pubmed publisher
Traka M, Podojil J, McCarthy D, Miller S, Popko B. Oligodendrocyte death results in immune-mediated CNS demyelination. Nat Neurosci. 2016;19:65-74 pubmed publisher
He L, Zhang Y, Ma G, Tan P, Li Z, Zang S, et al. Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation. elife. 2015;4: pubmed publisher
Chenery A, Antignano F, Burrows K, Scheer S, Perona Wright G, Zaph C. Low-Dose Intestinal Trichuris muris Infection Alters the Lung Immune Microenvironment and Can Suppress Allergic Airway Inflammation. Infect Immun. 2016;84:491-501 pubmed publisher
Rezende R, da Cunha A, Kuhn C, Rubino S, M Hamdi H, Gabriely G, et al. Identification and characterization of latency-associated peptide-expressing γδ T cells. Nat Commun. 2015;6:8726 pubmed publisher
Kawahara M, Takaku H. A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells. Cancer Biol Ther. 2015;16:1616-25 pubmed publisher
Guo A, He D, Xu H, Geng C, Zhao J. Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents. Sci Rep. 2015;5:14046 pubmed publisher
Wang X, Huang Z, Chen Y, Lu X, Zhu P, Wen K, et al. A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus. PLoS ONE. 2015;10:e0136888 pubmed publisher
Park C, Arthos J, Cicala C, Kehrl J. The HIV-1 envelope protein gp120 is captured and displayed for B cell recognition by SIGN-R1(+) lymph node macrophages. elife. 2015;4: pubmed publisher
Ampem G, Azegrouz H, Bacsadi Ã, Balogh L, Schmidt S, Thuróczy J, et al. Adipose tissue macrophages in non-rodent mammals: a comparative study. Cell Tissue Res. 2016;363:461-78 pubmed publisher
Arbelaez C, Glatigny S, Duhen R, Eberl G, Oukka M, Bettelli E. IL-7/IL-7 Receptor Signaling Differentially Affects Effector CD4+ T Cell Subsets Involved in Experimental Autoimmune Encephalomyelitis. J Immunol. 2015;195:1974-83 pubmed publisher
Vogel A, Brown D. Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells. Front Immunol. 2015;6:327 pubmed publisher
Rose A, Hoffmann F, Hara J, Urschitz J, Moisyadi S, Hoffmann P, et al. Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses. Hum Vaccin Immunother. 2015;11:2305-11 pubmed publisher
Li X, Xu J, Lv Z, Wang J, Sun S, Zhu W, et al. Inadequate activation of the HBsAg-specific Th cells by APCs leads to hyporesponsiveness to HBsAg vaccine in B10.S mice. Hum Vaccin Immunother. 2015;11:1735-43 pubmed publisher
Reis B, Lee K, Fanok M, Mascaraque C, Amoury M, Cohn L, et al. Leptin receptor signaling in T cells is required for Th17 differentiation. J Immunol. 2015;194:5253-60 pubmed publisher
Teng X, Tian M, Li J, Tan S, Yuan X, Yu Q, et al. Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine. Hum Vaccin Immunother. 2015;11:1456-64 pubmed publisher
Wiesner D, Specht C, Lee C, Smith K, Mukaremera L, Lee S, et al. Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection. PLoS Pathog. 2015;11:e1004701 pubmed publisher
Annemann M, Wang Z, Plaza Sirvent C, Glauben R, Schuster M, Ewald Sander F, et al. IκBNS regulates murine Th17 differentiation during gut inflammation and infection. J Immunol. 2015;194:2888-98 pubmed publisher
Santori F, Huang P, van de Pavert S, Douglass E, Leaver D, Haubrich B, et al. Identification of natural RORγ ligands that regulate the development of lymphoid cells. Cell Metab. 2015;21:286-298 pubmed publisher
Tassi I, Rikhi N, Claudio E, Wang H, Tang W, Ha H, et al. The NF-κB regulator Bcl-3 modulates inflammation during contact hypersensitivity reactions in radioresistant cells. Eur J Immunol. 2015;45:1059-1068 pubmed publisher
Niebling J, E Rünker A, Schallenberg S, Kretschmer K, Kempermann G. Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms. F1000Res. 2014;3:169 pubmed publisher
Donnelly R, Loftus R, Keating S, Liou K, Biron C, Gardiner C, et al. mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function. J Immunol. 2014;193:4477-84 pubmed publisher
Tassi I, Claudio E, Wang H, Tang W, Ha H, Saret S, et al. The NF-κB regulator Bcl-3 governs dendritic cell antigen presentation functions in adaptive immunity. J Immunol. 2014;193:4303-11 pubmed publisher
Gibbins J, Ancelet L, Weinkove R, Compton B, Painter G, Petersen T, et al. An autologous leukemia cell vaccine prevents murine acute leukemia relapse after cytarabine treatment. Blood. 2014;124:2953-63 pubmed publisher
Duval A, Fuertes Marraco S, Schwitter D, Leuenberger L, Acha Orbea H. Large T Antigen-Specific Cytotoxic T Cells Protect Against Dendritic Cell Tumors through Perforin-Mediated Mechanisms Independent of CD4 T Cell Help. Front Immunol. 2014;5:338 pubmed publisher
Cheng M, Qian L, Shen G, Bian G, Xu T, Xu W, et al. Microbiota modulate tumoral immune surveillance in lung through a ??T17 immune cell-dependent mechanism. Cancer Res. 2014;74:4030-41 pubmed publisher
Bryant J, Lerret N, Wang J, Kang H, Tasch J, Zhang Z, et al. Preemptive donor apoptotic cell infusions induce IFN-?-producing myeloid-derived suppressor cells for cardiac allograft protection. J Immunol. 2014;192:6092-101 pubmed publisher
Lindenstrøm T, Aagaard C, Christensen D, Agger E, Andersen P. High-frequency vaccine-induced CD8⁺ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protection. Eur J Immunol. 2014;44:1699-709 pubmed publisher
Wang Z, Friedrich C, Hagemann S, Korte W, Goharani N, Cording S, et al. Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium. Mucosal Immunol. 2014;7:1290-301 pubmed publisher
Huang W, Qi Q, Hu J, Huang F, Laufer T, August A. Dendritic cell-MHC class II and Itk regulate functional development of regulatory innate memory CD4+ T cells in bone marrow transplantation. J Immunol. 2014;192:3435-3441 pubmed publisher
Reba S, Li Q, Onwuzulike S, Ding X, Karim A, Hernandez Y, et al. TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis. Eur J Immunol. 2014;44:1410-21 pubmed publisher
Savolainen L, Koskivirta P, Kantele A, Valleala H, Pusa L, Tuompo R, et al. Cytotoxic response persists in subjects treated for tuberculosis decades ago. BMC Infect Dis. 2013;13:573 pubmed publisher
Wang S, Wu B, Xue J, Wang M, Chen R, Wang B. Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge. Hum Vaccin Immunother. 2014;10:461-8 pubmed publisher
Obregón Henao A, Henao Tamayo M, Orme I, Ordway D. Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection. PLoS ONE. 2013;8:e80669 pubmed publisher
Carbo A, Bassaganya Riera J, Pedragosa M, Viladomiu M, Marathe M, Eubank S, et al. Predictive computational modeling of the mucosal immune responses during Helicobacter pylori infection. PLoS ONE. 2013;8:e73365 pubmed publisher
Wu B, Zou Q, Hu Y, Wang B. Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice. Hum Vaccin Immunother. 2013;9:2133-41 pubmed publisher
Reis B, Rogoz A, Costa Pinto F, Taniuchi I, Mucida D. Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4? T cell immunity. Nat Immunol. 2013;14:271-80 pubmed publisher
Wan W, Lionakis M, Liu Q, Roffe E, Murphy P. Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice. Cardiovasc Res. 2013;97:580-8 pubmed publisher
Getts D, Martin A, McCarthy D, Terry R, Hunter Z, Yap W, et al. Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis. Nat Biotechnol. 2012;30:1217-24 pubmed publisher
Gong Y, Wang Z, Liang Z, Duan H, Ouyang L, Yu Q, et al. Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells. PLoS ONE. 2012;7:e47435 pubmed publisher
Hall A, Beiting D, Tato C, John B, Oldenhove G, Lombana C, et al. The cytokines interleukin 27 and interferon-? promote distinct Treg cell populations required to limit infection-induced pathology. Immunity. 2012;37:511-23 pubmed publisher
Hayashi C, Papadopoulos G, Gudino C, Weinberg E, Barth K, Madrigal A, et al. Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen. J Immunol. 2012;189:3681-8 pubmed
Lindenstrøm T, Woodworth J, Dietrich J, Aagaard C, Andersen P, Agger E. Vaccine-induced th17 cells are maintained long-term postvaccination as a distinct and phenotypically stable memory subset. Infect Immun. 2012;80:3533-44 pubmed publisher
Oh S, Aitken M, Simons D, Basehoar A, Garcia V, Kropf E, et al. Requirement for diverse TCR specificities determines regulatory T cell activity in a mouse model of autoimmune arthritis. J Immunol. 2012;188:4171-80 pubmed publisher
Seedhom M, Mathurin K, Kim S, Welsh R. Increased protection from vaccinia virus infection in mice genetically prone to lymphoproliferative disorders. J Virol. 2012;86:6010-22 pubmed publisher
Goicochea M, Zapata J, Bryant J, Davis H, Salvato M, Lukashevich I. Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model. Vaccine. 2012;30:1445-52 pubmed publisher
Tian L, De Hertogh G, Fedeli M, Staats K, Schonefeldt S, Humblet Baron S, et al. Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice. J Autoimmun. 2012;38:39-48 pubmed publisher
Leepiyasakulchai C, Ignatowicz L, Pawlowski A, Kallenius G, Sköld M. Failure to recruit anti-inflammatory CD103+ dendritic cells and a diminished CD4+ Foxp3+ regulatory T cell pool in mice that display excessive lung inflammation and increased susceptibility to Mycobacterium tuberculosis. Infect Immun. 2012;80:1128-39 pubmed publisher
Roffê E, Rothfuchs A, Santiago H, Marino A, Ribeiro Gomes F, Eckhaus M, et al. IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection. J Immunol. 2012;188:649-60 pubmed publisher
Tian L, Altin J, Makaroff L, Franckaert D, Cook M, Goodnow C, et al. Foxp3? regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis. Blood. 2011;118:1845-53 pubmed publisher
Wojno E, Hosken N, Stumhofer J, O Hara A, Mauldin E, Fang Q, et al. A role for IL-27 in limiting T regulatory cell populations. J Immunol. 2011;187:266-73 pubmed publisher
Schmidt N, Harty J. Cutting edge: attrition of Plasmodium-specific memory CD8 T cells results in decreased protection that is rescued by booster immunization. J Immunol. 2011;186:3836-40 pubmed publisher
Overstreet M, Chen Y, Cockburn I, Tse S, Zavala F. CD4+ T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoites. PLoS ONE. 2011;6:e15948 pubmed publisher
Zaborsky N, Brunner M, Wallner M, Himly M, Karl T, Schwarzenbacher R, et al. Antigen aggregation decides the fate of the allergic immune response. J Immunol. 2010;184:725-35 pubmed publisher
Lindenstrøm T, Agger E, Korsholm K, Darrah P, Aagaard C, Seder R, et al. Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells. J Immunol. 2009;182:8047-55 pubmed publisher
product information
Product Type :
Antibody
Product Name :
IFN gamma Monoclonal Antibody (XMG1.2), PE-Cyanine7, eBioscience™
Catalog # :
25-7311-41
Quantity :
25 Tests
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 5 µL (0.25 µg)/test
Species :
Mouse
Clone :
XMG1.2
Isotype :
IgG1, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines. Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway. IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma. IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. IFN gamma gene mutations are associated with aplastic anemia.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 µL (0.25 µg)/test
Aliases :
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA