MHC Class I (H-2Db) Monoclonal Antibody (28-14-8), PE-Cyanine7, eBioscience | Invitrogen 25-5999-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MHC Class I (H-2Db) Monoclonal Antibody (28-14-8), PE-Cyanine7, eBioscience

catalog :

25-5999-82

quantity :

100 µg

price :

US 394

clonality :

monoclonal

host :

mouse

conjugate :

PE/Cy7

clone name :

28-14-8

The same clone is also sold as:

OriGene: AM08080PU-N, AM08080RP-N, AM08080LE-N, AM08080FC-N, AM08080BT-N
BioLegend: 114502, 114507
Abcam: ab171283

reactivity :

mouse

application :

flow cytometry

citations: 3

Reference
Westrich J, Vermeer D, Silva A, Bonney S, Berger J, Cicchini L, et al. CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression. Oncogene. 2019;: pubmed publisher
Buxade M, Huerga Encabo H, Riera Borrull M, Quintana Gallardo L, López Cotarelo P, Tellechea M, et al. Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5. J Exp Med. 2018;215:2901-2918 pubmed publisher
Ahn R, Sabourin V, Bolt A, Hebert S, Totten S, De Jay N, et al. The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression. Nat Commun. 2017;8:14638 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MHC Class I (H-2Db) Monoclonal Antibody (28-14-8), PE-Cyanine7, eBioscience

Catalog # :

25-5999-82

Quantity :

100 µg

Price :

US 394

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Mouse

Applications :

Flow Cytometry: 1.0 µg/test

Species :

Mouse

Clone :

28-14-8

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

This protein is an MHC class I alloantigen, which is involved in antigen presentation to T cells expressing CD3/TCR and CD8. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1.0 µg/test

Aliases :

H-2 class I histocompatibility antigen, D-B alpha chain; H-2D; H2-D; H-2D cell surface glycoprotein; H-2D(B); H2D1; H2-D1; H2DB; H2-DC1-beta transplantation antigen protein; H2L; H2LD; histocompatibility 2, D region locus 1; MHC class I antigen; MHC class I H2 antigen; MHC class I H-2Dp; MHC H2-D-q alpha-chain; Q5k protein