This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD93 (AA4.1) Monoclonal Antibody (AA4.1), PE-Cyanine7, eBioscience™
catalog :
25-5892-81
quantity :
50 µg
price :
US 309.00
clonality :
monoclonal
host :
rat
conjugate :
PE/Cy7
clone name :
AA4.1
reactivity :
mouse
application :
flow cytometry
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 3
Vink P, Smout W, Driessen Engels L, de Bruin A, Delsing D, Krajnc Franken M, et al. In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation. PLoS ONE. 2013;8:e57348 pubmed publisher
Weng Q, Hu F, Zhang M, Dong Y, Lv C, Wang Y, et al. A protocol for generating induced T cells by reprogramming B cells in vivo. Cell Regen (Lond). 2018;7:7-15 pubmed publisher
Frasca D, Diaz A, Romero M, Vazquez T, Blomberg B. Obesity induces pro-inflammatory B cells and impairs B cell function in old mice. Mech Ageing Dev. 2017;162:91-99 pubmed publisher
Lin C, Bradstreet T, Schwarzkopf E, Jarjour N, Chou C, Archambault A, et al. IL-1-induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation. J Exp Med. 2016;213:251-71 pubmed publisher
Yang Y, Wang C, Yang Q, Kantor A, Chu H, Ghosn E, et al. Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires. elife. 2015;4:e09083 pubmed publisher
Iwasaki M, LIEDTKE M, Gentles A, Cleary M. CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia. Cell Stem Cell. 2015;17:412-21 pubmed publisher
Palmer V, Aziz Seible R, Kassmeier M, Rothermund M, Perry G, Swanson P. VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection. J Immunol. 2015;195:1524-37 pubmed publisher
Granato A, Hayashi E, Baptista B, Bellio M, Nobrega A. IL-4 regulates Bim expression and promotes B cell maturation in synergy with BAFF conferring resistance to cell death at negative selection checkpoints. J Immunol. 2014;192:5761-75 pubmed publisher
Ratliff M, Alter S, Frasca D, Blomberg B, Riley R. In senescence, age-associated B cells secrete TNF? and inhibit survival of B-cell precursors. Aging Cell. 2013;12:303-11 pubmed publisher
Yu M, Chen Y, He Y, Podd A, Fu G, Wright J, et al. Critical role of B cell lymphoma 10 in BAFF-regulated NF-?B activation and survival of anergic B cells. J Immunol. 2012;189:5185-93 pubmed publisher
Königsberger S, Peckl Schmid D, Zaborsky N, Patzak I, Kiefer F, Achatz G. HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion. PLoS ONE. 2010;5: pubmed publisher
Hayashi E, Granato A, Paiva L, Bertho A, Bellio M, Nobrega A. TLR4 promotes B cell maturation: independence and cooperation with B lymphocyte-activating factor. J Immunol. 2010;184:4662-72 pubmed publisher
Duong B, Ota T, Ait Azzouzene D, Aoki Ota M, VELA J, Huber C, et al. Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen. J Immunol. 2010;184:4143-58 pubmed publisher
Yunk L, Meng W, Cohen P, Eisenberg R, Luning Prak E. Antibodies in a heavy chain knock-in mouse exhibit characteristics of early heavy chain rearrangement. J Immunol. 2009;183:452-61 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD93 (AA4.1) Monoclonal Antibody (AA4.1), PE-Cyanine7, eBioscience™
Catalog # :
25-5892-81
Quantity :
50 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 µg/test
Species :
Mouse
Clone :
AA4.1
Isotype :
IgG2b, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 µg/test
Aliases :
6030404G09Rik; AA145088; Aa4; AA4.1; AW555904; C1q receptor; C1q receptor 1; C1q/MBL/SPA receptor; C1qR; C1qR(P); C1qr1; C1qRP; Cd93; CD93 antigen; CD93 molecule; CDw93; Cell surface antigen AA4; complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; ly-68; Lymphocyte antigen 68; matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA