CD335 (NKp46) Monoclonal Antibody (29A1.4), PE-Cyanine7, eBioscience | Invitrogen 25-3351-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD335 (NKp46) Monoclonal Antibody (29A1.4), PE-Cyanine7, eBioscience

catalog :

25-3351-80

quantity :

25 µg

price :

US 157.00

clonality :

monoclonal

host :

rat

conjugate :

PE/Cy7

clone name :

29A1.4

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 29

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:50	Klose R, Krzywinska E, Castells M, Gotthardt D, Putz E, Kantari Mimoun C, et al. Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia. Nat Commun. 2016;7:12528 pubmed publisher
	Chu S, Ma L, Yang X, Xiao B, Liang Y, Zheng S, et al. NCR negative group 3 innate lymphoid cell (NCR- ILC3) participates in abnormal pathology of lung in cigarette smoking-induced COPD mice. Immun Inflamm Dis. 2023;11:e816 pubmed publisher
	Patton T, Zhao Z, Lim X, Eddy E, Wang H, Nelson A, et al. RIPK3 controls MAIT cell accumulation during development but not during infection. Cell Death Dis. 2023;14:111 pubmed publisher
	Li K, Meza Guzman L, Whitehead L, Leong E, Kueh A, Alexander W, et al. SOCS2 regulation of growth hormone signaling requires a canonical interaction with phosphotyrosine. Biosci Rep. 2022;42: pubmed publisher
	Song X, Li N, Liu Y, Wang Z, Wang T, Tan S, et al. CD169-positive macrophages enhance abscopal effect of radiofrequency ablation therapy in liver cancer. Transl Oncol. 2022;15:101306 pubmed publisher
	Aschman T, Schaffer S, Biniaris Georgallis S, Triantafyllopoulou A, Staeheli P, Voll R. Interferon Lambda Regulates Cellular and Humoral Immunity in Pristane-Induced Lupus. Int J Mol Sci. 2021;22: pubmed publisher
	Sobecki M, Krzywinska E, Nagarajan S, Audig xe9 A, Hu x1ef3 nh K, Zacharjasz J, et al. NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence. Nat Commun. 2021;12:4700 pubmed publisher
	Wong P, Wagner J, Berrien Elliott M, Schappe T, Fehniger T. Flow cytometry-based ex vivo murine NK cell cytotoxicity assay. STAR Protoc. 2021;2:100262 pubmed publisher
	Cho S, Rudloff I, Lao J, Pang M, Goldberg R, Bui C, et al. Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities. Nat Commun. 2020;11:5794 pubmed publisher
	Goh W, Scheer S, Jackson J, Hediyeh Zadeh S, Delconte R, Schuster I, et al. Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance. Cell Rep. 2020;33:108285 pubmed publisher
	Wagner J, Wong P, Schappe T, Berrien Elliott M, Cubitt C, Jaeger N, et al. Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity. Cell Rep. 2020;31:107720 pubmed publisher
	Dietschmann A, Schruefer S, Krappmann S, Voehringer D. Th2 cells promote eosinophil-independent pathology in a murine model of allergic bronchopulmonary aspergillosis. Eur J Immunol. 2020;50:1044-1056 pubmed publisher
	Park M, Kim H, Lee H, Zabel B, Bae Y. Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection. Sci Adv. 2020;6:eaax8820 pubmed publisher
	Blagih J, Zani F, Chakravarty P, Hennequart M, Pilley S, Hobor S, et al. Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses. Cell Rep. 2020;30:481-496.e6 pubmed publisher
	Zhang X, Feng J, Chen S, Yang H, Dong Z. Synergized regulation of NK cell education by NKG2A and specific Ly49 family members. Nat Commun. 2019;10:5010 pubmed publisher
	Sifuentes Dominguez L, Li H, Llano E, Liu Z, Singla A, Patel A, et al. SCGN deficiency results in colitis susceptibility. elife. 2019;8: pubmed publisher
	Pascual García M, Bonfill Teixidor E, Planas Rigol E, Rubio Perez C, Iurlaro R, Arias A, et al. LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy. Nat Commun. 2019;10:2416 pubmed publisher
	Van der Spek A, Surovtseva O, Jim K, van Oudenaren A, Brouwer M, Vandenbroucke Grauls C, et al. Regulation of Intracellular Triiodothyronine Is Essential for Optimal Macrophage Function. Endocrinology. 2018;159:2241-2252 pubmed publisher
	Li Q, Li D, Zhang X, Wan Q, Zhang W, Zheng M, et al. E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor. Immunity. 2018;48:258-270.e5 pubmed publisher
	Van der Spek A, Jim K, Karaczyn A, van Beeren H, Ackermans M, Darras V, et al. The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species. Endocrinology. 2018;159:826-835 pubmed publisher
	Krzywinska E, Kantari Mimoun C, Kerdiles Y, Sobecki M, Isagawa T, Gotthardt D, et al. Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis. Nat Commun. 2017;8:1597 pubmed publisher
	Cuff A, Male V. Conventional NK cells and ILC1 are partially ablated in the livers of Ncr1 iCreTbx21 fl/fl mice. Wellcome Open Res. 2017;2:39 pubmed publisher
	Kantari Mimoun C, Krzywinska E, Castells M, Milien C, Klose R, Meinecke A, et al. Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice. Oncotarget. 2017;8:15085-15100 pubmed publisher
	Yang M, Chen S, Du J, He J, Wang Y, Li Z, et al. NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. Nat Commun. 2016;7:12730 pubmed publisher
	Pettini E, Fiorino F, Cuppone A, Iannelli F, Medaglini D, Pozzi G. Interferon-Î³ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae. Front Microbiol. 2015;6:1340 pubmed publisher
	Krneta T, Gillgrass A, Chew M, Ashkar A. The breast tumor microenvironment alters the phenotype and function of natural killer cells. Cell Mol Immunol. 2016;13:628-39 pubmed publisher
	Ota N, Wong K, Valdez P, Zheng Y, Crellin N, Diehl L, et al. IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium. Nat Immunol. 2011;12:941-8 pubmed publisher
	Walzer T, Chiossone L, Chaix J, Calver A, Carozzo C, Garrigue Antar L, et al. Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor. Nat Immunol. 2007;8:1337-44 pubmed
	Walzer T, Blery M, Chaix J, Fuseri N, Chasson L, Robbins S, et al. Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46. Proc Natl Acad Sci U S A. 2007;104:3384-9 pubmed

product information

Product Type :

Antibody

Product Name :

CD335 (NKp46) Monoclonal Antibody (29A1.4), PE-Cyanine7, eBioscience

Catalog # :

25-3351-80

Quantity :

25 µg

Price :

US 157.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 µg/test

Species :

Mouse

Clone :

29A1.4

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

NKp46 (CD335, NCR1, ) is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp46 consists of two Ig-like domains assembled to leukocyte immunoglobulin-like (LIR) and killer inhibitory receptors (KIR).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test

Aliases :

1-Mar; activating receptor 1; Ar1; CD335; hNKp46; Kilr1; KILR-1; LY94; Ly-94; lymphocyte antigen 94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); mAR-1; MAR1 (mouse activating receptor 1); mNKp46; natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; Ncr1; NK cell-activating receptor; NK receptor KILR-1; NKACTR; Nkp46; NK-p46; NK-p46); rAR-1; rat-activating receptor 1

more info or order :

Invitrogen product webpage